Live data from Hacker News

Effect of early treatment with fluvoxamine on risk of hospitalization for Covid

thelancet.com

61–70 of 127 posts

Re: Effect of early treatment with fluvoxamine on risk of hospitalization for Covid

#61

Earlier quoted context omitted.

>Prior to studies being done, how do we evaluate who is a quack and who is correct You allow the dialog to take place and make up your own mind. >I would argue that anyone who had a solution to Covid should rush to get it published in a reputable Any tool thats not a vaccine gets associated with Trump or the right wing and is dismissed. Its even stifled funding for anti-virals that give a 50% reduction in hospitaliza…

> You allow the dialog to take place and make up your own mind. I'm not sure this applies to medicine or vaccines. I don't think any of us are in the position of "making up our own mind" about what works in medicine and what doesn't, which is why we have double-blind clinical studies. We can't even explain why/how placebo works.

You have to be in the position of being your own medical advocate.

I had a condition that was misdiagnosed repeatedly, including in the ER. My condition is not even "rare", just slightly uncommon, and I had a very textbook case of it.

Your doctor is not an oracle. They are a car mechanic that works on organics.

Re: Effect of early treatment with fluvoxamine on risk of hospitalization for Covid

#62
post #8

Earlier quoted context omitted.

I think the issue is how was it proven back then? There are a lot of people promoting ideas, some of which will eventually get clinical backing that they are correct. Prior to studies being done, how do we evaluate who is a quack and who is correct? There is a lot of harm promoting quack ideas during a pandemic. Based on reputation? Twitter followers? Their passion? I do not believe anyone censored research and scien…

>Prior to studies being done, how do we evaluate who is a quack and who is correct You allow the dialog to take place and make up your own mind. >I would argue that anyone who had a solution to Covid should rush to get it published in a reputable Any tool thats not a vaccine gets associated with Trump or the right wing and is dismissed. Its even stifled funding for anti-virals that give a 50% reduction in hospitaliza…

>> You allow the dialog to take place and make up your own mind.

I have reviewed all of the available dialog, and I have concluded that not only is the coronavirus fake, the world is flat.

Re: Effect of early treatment with fluvoxamine on risk of hospitalization for Covid

#63

Earlier quoted context omitted.

There are plenty of Facebook and YouTube guides about taking animal ivermectin as a replacement for human-rated medicine. That said hopefully here on HN we can agree that is a dumb idea.

If the government were stupid and tyrranical enough to ban Human Azithromycin, and you came down with bacterial bronchitis, would you just die or would you go to the local feed store and buy some animal grade azithromycin?

That seems like a false choice

Re: Effect of early treatment with fluvoxamine on risk of hospitalization for Covid

#64

Earlier quoted context omitted.

>Prior to studies being done, how do we evaluate who is a quack and who is correct You allow the dialog to take place and make up your own mind. >I would argue that anyone who had a solution to Covid should rush to get it published in a reputable Any tool thats not a vaccine gets associated with Trump or the right wing and is dismissed. Its even stifled funding for anti-virals that give a 50% reduction in hospitaliza…

>> You allow the dialog to take place and make up your own mind. I have reviewed all of the available dialog, and I have concluded that not only is the coronavirus fake, the world is flat.

Additionally, after further review, I know that birds aren't real, if I need to charge my iphone quickly I can do so in the microwave, smoking isn't harmful and climate change isn't real.

Re: Effect of early treatment with fluvoxamine on risk of hospitalization for Covid

#65
post #30

Earlier quoted context omitted.

Why does it say: > We found a clinically important absolute risk reduction of 5·0%, and 32% RR reduction, on the primary outcome of hospitalisation Why is the absolute 5% and the RR 32%? What's the difference? Also why does it say: > There were no significant differences between fluvoxamine and placebo for viral clearance at day 7 (p=0·090) and hospitalisations due to COVID (p=0·10), all-cause hospitalisations (p=0·0…

>Why is the absolute 5% and the RR 32%? What's the difference? Absolute reduction is compared to control in absolute terms (16% hospitalized in control minus 11% with treatment = 5%). Relative risk reduction is the absolute reduction divided by hospitalizations in the control (5%/16%) Absolute % tells you how big the effect is, relative risk tells you how big it is in comparison to the reference. >Why wouldn't they m…

Thanks for the explanation, I can much better understand the data now.

What about the BCI? How does the Bayesian confidence interval and the P value differ ?

Re: Effect of early treatment with fluvoxamine on risk of hospitalization for Covid

#66
This is fascinating, but for people who already have a medical history of ITP, it might be a bad idea, as this drug has known anti-platelet activity. Good for "normal" people to avoid blood clots, but bad for ITP people who are trying to keep from losing platelets.

Re: Effect of early treatment with fluvoxamine on risk of hospitalization for Covid

#67
post #8
post #5

What's interesting is Steve Kirsch was touting this months ago alongside Robert Malone and Bret Weinstein. That content got banned from YouTube. Was more or less harm done by stifling this information? In the desire to drive official therapeutics and vaccines was this potentially not surfaced as fast as it could have been? I'm not sure. It's good food for thought though.

I think the issue is how was it proven back then? There are a lot of people promoting ideas, some of which will eventually get clinical backing that they are correct. Prior to studies being done, how do we evaluate who is a quack and who is correct? There is a lot of harm promoting quack ideas during a pandemic. Based on reputation? Twitter followers? Their passion? I do not believe anyone censored research and scien…

Yes, but why should people who are calling for studies to be done get censored? Scientists who are talking about interesting possibilities that _should_be_studied_ should not get their content taken down.

Re: Effect of early treatment with fluvoxamine on risk of hospitalization for Covid

#68

Earlier quoted context omitted.

It's useful to note that c19early is backed/funded by FLCCC, which has been widely reported to be a "fringe doctor's" group. https://www.scientificamerican.com/article/fringe-doctors-gr... It's also worth noting that the site/group has been banned from Twitter for spreading misinformation about treatment options.

Welcome to the Circular Logic Merry Go Round, where we need to ban people because they're wrong because of course they're wrong, they were banned on twitter....

More of a slide than a merry go round if it starts at Twitter based on FDA established fact, I would say

Re: Effect of early treatment with fluvoxamine on risk of hospitalization for Covid

#69

Earlier quoted context omitted.

> The government could have spent the last 18 months encouraging people to lose weight, stop smoking, drinking, and eating fast food. Instead, the "solution" did the opposite. But worse, kids stayed inside, didn't exercise, put on (likely more) weight, didn't share illness (read: weakened immune system) and then those kids were ordered back to school in that highly vulnerable state. The solution? The jab. With absolu…

If you seriously think the government could have made us all lose weight in the last 18 months... they’ve been running anti obesity campaigns for decades and failing while obesity grows every year. BTW covid is plenty dangerous to non obese as well. The vaccine shot actually works well and is incredibly easy to use compared to a grueling year long weight loss and sustaining it for a lifetime, for most people.

These public health “experts” didn’t even try. They basically treated covid like it was the Black Plague for everybody, when that is far from the truth. The truth is covid is a risk for a very specific set of the population.

They made very little (no?) mention of how most people recover just fine. No mention of how stratified the risks are based on age. No mention about how it goes after the obese. None of that. Instead they just focused on scaring the shit out of everybody so bad I think many will suffer from PTSD.

These health “experts” failed horribly at communicating the basic facts about covid.

Re: Effect of early treatment with fluvoxamine on risk of hospitalization for Covid

#70
post #56

Earlier quoted context omitted.

>The other issue is they all mention requiring early treatment, but tests and other ways to detect Covid early aren't readily available or cheap, so do you now take this giant cocktail of mixed drugs every time you have a cold in case it turns out to be early onset Covid? Do you just take them all on a regular basis as a preventative? This is mostly a self imposed US problem. In many parts of Europe, you can get a ra…

Is that their actual cost or are they subsidized? Also, I thought that even with symptoms the false positive rate was about 30% for rapid tests. If so, just that would possibly offset the effect of the best currently known treatment which based on the OPs website is fluvoxamine and the study here says a 32% reduction. But if about 30% of people who have Covid think they don't because of the false positive rate of the…

I wasn't making a value judgment on if tests+ treatment is superior to vaccination, just that it is an artificial limitation.

I don't know if they are subsidized.

Post reply on HN