Israel’s Covid-19 boosters are preventing infections, new studies suggest • Hacker News Board

Re: Israel’s Covid-19 boosters are preventing infections, new studies suggest

#271

Post by manofmanysmiles » Thu, Sep 02, 2021, 12:29 AM UTC

hwillis wrote: post #207

manofmanysmiles wrote: post #161

Earlier quoted context omitted.

Certain virus do in fact modify the DNA in cells[1]. From the article: > Some types of virus, such as retroviruses, integrate their genetic material (including the new gene) into a chromosome in the human cell. Therefore the claim that an injection of RNA could modify your DNA is possible. Whether the COVID injections do this is a different story, and seems unlikely. [1] https://medlineplus.gov/genetics/understanding…

> Therefore the claim that an injection of RNA could modify your DNA is possible. Absolutely not. This is like saying water is a neurotoxin because a tiny subset of neurotoxins contain water. Or that almost any food can modify your dna, since mRNA, RNA and DNA are in any cells you eat. reverse transcription doesn't just happen . Retroviruses work because they carry reverse transcriptase: https://en.wikipedia.org/wiki…

I’m not saying the vaccines do this, just that it’s theoretically possible to make a gene therapy that does modify DNA.

Re: Israel’s Covid-19 boosters are preventing infections, new studies suggest

#272

Post by fomine3 » Thu, Sep 02, 2021, 2:32 AM UTC

legerdemain wrote: post #246

hackingforfun wrote: post #73

I'm pretty surprised to still see some misinformation in some of the posts here. I have a friend who has a PhD in molecular biology and she described the mRNA vaccines to me. The mRNA is only a piece of the spike protein, and does not enter the cell's nucleus. It only interacts with the cytoplasm. Normally, if a cell had to deal with an actual SARS-CoV-2 virus, it would be dealing with the spike proteins and the enti…

I see a lot of presumptions that Covid will "become like a common cold," but what separates this from dangerous wishful thinking? Humanity suffered from smallpox for centuries before it was finally eradicated. It's not clear that it was becoming meaningfully less severe. Dengue is endemic in tropical regions. A reinfection often leads to severe disease. Yellow fever did not get better over time. We vaccinated actual…

Some common cold is caused by coronavirus (not covid-19) or other virus, but HIV/smallpox are far from cold virus.

Re: Israel’s Covid-19 boosters are preventing infections, new studies suggest

#273

Post by Izkata » Thu, Sep 02, 2021, 2:35 AM UTC

bart_spoon wrote: post #239

Izkata wrote: post #192

Earlier quoted context omitted.

Alabama: https://data.commercialappeal.com/covid-19-hospital-capacity... - Scrolling through these, it still looks like only 20-30% are covid. Arkansas: https://data.commercialappeal.com/covid-19-hospital-capacity... - Mostly not being overrun, and again covid is only like 20-30%. Florida: https://data.commercialappeal.com/covid-19-hospital-capacity... - Similar to Alabama, and like Alabama, mostly not covid. Georgia…

So why, in your opinion, are elective surgeries and deferred treatments only overrunning hospitals in states with lower vaccination rates? That's an especially strange assumption to make, given that said states also generally had the least restrictive lockdown measures from last year, meaning that if anything they would likely have fewer deferred treatments to perform now than states taking more intensive steps to ha…

> in states with lower vaccination rates?

Come to think of it, two of those states aren't near the bottom, so that's also just wrong: Texas and Florida are around the halfway point when the states are ranked by vaccination rate, Texas just below and Florida just above. [0]

So yeah, I definitely think there's something else going on.

[0] https://usafacts.org/visualizations/covid-vaccine-tracker-st...

Re: Israel’s Covid-19 boosters are preventing infections, new studies suggest

#274

Post by _red » Thu, Sep 02, 2021, 3:03 AM UTC

mikepurvis wrote: post #261

_red wrote: post #253

Earlier quoted context omitted.

>roughly 11 out of every 100 people in Sweden have been diagnosed with COVID-19, compared with 9.4 out of every 100 in the UK and 7.4 per 100 in Italy If the goal is to shoot for herd immunity, then you would need 40-60% of population to have antibodies. No way to get from A -> B without people 'catching it' At some point it needs to be accepted that Covid is now endemic and is 'never going away'. Trying to stave it…

Why jump to an assumption that there's a dark profit motive here? Isn't that what has led to people clinging to snake oil miracle cures like hydroxychloroquine and ivermectin? Certainly there was never any profit motive for anyone (except maybe Amazon and Uber Eats) when people were encouraging to stay home, or wear improvised masks. In any case, there is lots of study going on in this area— it's not like Pfizer and…

>Why jump to an assumption that there's a dark profit motive here?

Total legal immunity + gov mandates to buy your product. Thats probably the largest single profit motive that could possibly exist...I mean can you reasonably imagine a greater profit scenario?

Re: Israel’s Covid-19 boosters are preventing infections, new studies suggest

#275

Post by Vecr » Thu, Sep 02, 2021, 3:35 AM UTC

dogma1138 wrote: post #264

greenhatman wrote: post #249

Earlier quoted context omitted.

>your own cells to produce spike proteins similar to the ones sars-cov-2 does Does this destroy the cell used to make the spike proteins? Or does your immune system destroy the cells that made spike proteins?

No, it doesn’t work like that mRNA isn’t a virus or virus like it doesn’t hijacks the cell. The mRNA fragments are picked up by dendritic cells and antigens are produced. The antigens (and the mRNA itself) are then attacked by special proteins within your cells that are designed to destroy foreign or malformed proteins and the fragments of those destroyed antigens are then presented in the cell membrane for T and B c…

What about cytotoxic T cells? What would prevent them from killing the cell?

Re: Israel’s Covid-19 boosters are preventing infections, new studies suggest

#276

Post by quantumwoke » Thu, Sep 02, 2021, 4:27 AM UTC

criticaltinker wrote: post #241

armchairhacker wrote: post #221

Earlier quoted context omitted.

The risk of suffering long-term damage from getting covid unvaccinated is way higher than the risk of any long-term side effects from the vaccine or getting Covid vaccinated. Even if the former is low, there's no downside to getting the vaccine anyways. I can kind of understand if someone is avoiding the vaccine and also isolating themselves to protect against the virus, but I really just don't understand the risk-be…

> the amount of people suffering myocarditis and other vaccine complications is in the double-digits This is not true, according to the CDC (as of August 18th) there at least 742 cases of myocarditis and myopericarditis associated with vaccination, potentially upwards of ~1,300 [1]. For males age 16-17 the reporting rate of myopericarditis after 2 doses of Pfizer is 71.5 per 1 million doses administered (0.0071%) [1]…

I note you conveniently left out "reported" cases from your sentence. You are citing numbers reported by VAERS which is not at all the same as confirmed cases. Please don't fear-monger on HN.

Re: Israel’s Covid-19 boosters are preventing infections, new studies suggest

#277

Post by criticaltinker » Thu, Sep 02, 2021, 5:12 AM UTC

quantumwoke wrote: post #276

criticaltinker wrote: post #241

Earlier quoted context omitted.

> the amount of people suffering myocarditis and other vaccine complications is in the double-digits This is not true, according to the CDC (as of August 18th) there at least 742 cases of myocarditis and myopericarditis associated with vaccination, potentially upwards of ~1,300 [1]. For males age 16-17 the reporting rate of myopericarditis after 2 doses of Pfizer is 71.5 per 1 million doses administered (0.0071%) [1]…

I note you conveniently left out "reported" cases from your sentence. You are citing numbers reported by VAERS which is not at all the same as confirmed cases. Please don't fear-monger on HN.

I cited numbers reported by the CDC who reviewed VAERS reports and determined that a subset met the CDC’s own criteria.

I accurately transcribed facts from an official CDC document, and even linked the source, nothing more. Do you really think that is fear-mongering?

The CDC is actively investigating many of the reports, dismissing them as not confirmed is a bit disingenuous at the very least.

Re: Israel’s Covid-19 boosters are preventing infections, new studies suggest

#278

Post by ubercore » Thu, Sep 02, 2021, 6:39 AM UTC

criticaltinker wrote: post #277

quantumwoke wrote: post #276

Earlier quoted context omitted.

I note you conveniently left out "reported" cases from your sentence. You are citing numbers reported by VAERS which is not at all the same as confirmed cases. Please don't fear-monger on HN.

I cited numbers reported by the CDC who reviewed VAERS reports and determined that a subset met the CDC’s own criteria. I accurately transcribed facts from an official CDC document, and even linked the source, nothing more. Do you really think that is fear-mongering? The CDC is actively investigating many of the reports, dismissing them as not confirmed is a bit disingenuous at the very least.

I think parent is commenting here that the CDC is talking about self-reported data. We're not talking about a diagnosis from a doctor. Calling them "confirmed" is just as disingenuous, if I'm understanding the explanations in the slides you link.

Re: Israel’s Covid-19 boosters are preventing infections, new studies suggest

#279

Post by uniqueid » Thu, Sep 02, 2021, 6:42 AM UTC

ostenning wrote: post #250

criticaltinker wrote: post #241

Earlier quoted context omitted.

> the amount of people suffering myocarditis and other vaccine complications is in the double-digits This is not true, according to the CDC (as of August 18th) there at least 742 cases of myocarditis and myopericarditis associated with vaccination, potentially upwards of ~1,300 [1]. For males age 16-17 the reporting rate of myopericarditis after 2 doses of Pfizer is 71.5 per 1 million doses administered (0.0071%) [1]…

Personally, my heart & chest are still recovering from the second Pfizer shot, after having ECG, bloodwork and nearly going to the ER. Wont be getting a booster, thats for damned certain. I suspect the number to be significantly higher than whats reported.

Literally billions of people around the world have been vaccinated against Coronavirus now. How high can the chance of serious short-term side effects be?

Re: Israel’s Covid-19 boosters are preventing infections, new studies suggest

#280

Post by SergeAx » Thu, Sep 02, 2021, 6:59 AM UTC

NalNezumi wrote: post #123

hackingforfun wrote: post #73

I'm pretty surprised to still see some misinformation in some of the posts here. I have a friend who has a PhD in molecular biology and she described the mRNA vaccines to me. The mRNA is only a piece of the spike protein, and does not enter the cell's nucleus. It only interacts with the cytoplasm. Normally, if a cell had to deal with an actual SARS-CoV-2 virus, it would be dealing with the spike proteins and the enti…

I have never ever on HN seen an argument about DNA and mRNA, but then again I don't follow the conversation too much. As it seems like you know someone with correct background on the subject, so I wanted to ask you something I've always wanted to know as a young,(late 20s) healthy person with no existing risky precondition in this pandemic: Why should I take a vaccine, when it is now known that vaccinated people can…

This is a false dichotomy: low risk hospitalization vs unknown long term side effects of the vaccine. The correct choice is unknown long term side effects of COVID-19 vs unknown long term side effects of vaccine.

In other words: you will get your immunity either by becoming sick (and maybe get well known short term side effects of being sick, including hospitalization and death) or by getting vaccinated, with other set of short and long term known and unknown side effects. In the first case you will put more pressure to public health system (even by staying home and consuming self-prescripted basic drugs). Otherwise the choice is yours.