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Valneva and Pfizer announce Phase 2 study for Lyme disease vaccine candidate

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31–40 of 271 posts

Re: Valneva and Pfizer announce Phase 2 study for Lyme disease vaccine candidate

#31
post #7

Why is it a vaccine? Are there going to be vaccine for everything in the future?

I think thanks to Covid booster shots they realise they can pivot to a Vaccine-as-a-Service model and create all sorts of recurring revenue streams.

Re: Valneva and Pfizer announce Phase 2 study for Lyme disease vaccine candidate

#33

The first vaccine had a problem where it gave people Lyme every once in a while. My hypothesis is that Lyme disease is an autoimmune disease caused by being exposed too acutely in some way, or for too long. For some people, a tick byte isn’t enough exposure to trigger it. For others, the vaccine is enough. They didn’t catch it early in clinical trials because those people are rare enough to not show up in small studi…

> The first vaccine had a problem where it gave people Lyme every once in a while.

Do you have a citation for that? The FDA review didn’t mention that:

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2870557/

Re: Valneva and Pfizer announce Phase 2 study for Lyme disease vaccine candidate

#34

Prepare to read the headline "mRNA vaccine trial for " a lot in the future. My guess is that they are going to produce mRNA versions of basically any vaccine (and then some) in the future. The nice thing about the technology seems to be that you only need to exchange the mRNA payload while the surrounding delivery method can be reused. That makes it not only a fast method to create a vaccine but a very convenient way…

Does anyone know why they haven't released a Delta varient vaccine? Is seems that it would just involved we changing the mRNA sequence in a computer at the factor, but I'm really just guessing. Also maybe it is considered a whole new vaccineand needs to go through approval again.

Probably because going through another round of certification is harder than using the existing vaccine as a booster, the hope being that this will already significantly improve delta resistance.

Re: Valneva and Pfizer announce Phase 2 study for Lyme disease vaccine candidate

#35
post #3

Ever since I moved to the 'first world' I've been scared of this disease. We don't have it where I come from and the long term effects sound straight up terrible.

It's nothing compared to the other tick disease: tick borne encephalitis. Thankfully there's a vaccine against that

Is that the one that makes you deathly allergic to beef or something?

Re: Valneva and Pfizer announce Phase 2 study for Lyme disease vaccine candidate

#36
post #7

Why is it a vaccine? Are there going to be vaccine for everything in the future?

Should we have a vaccine for addictions? alcoholism? drug use? eating?

Eg: Give it early in people's lives, that the first time they drink even a little alcohol, it should produce such (non life threatening) symptoms - terrible taste, throw up etc, they would not touch it again, and therefore won't be addicted?

Re: Valneva and Pfizer announce Phase 2 study for Lyme disease vaccine candidate

#37
post #8

Earlier quoted context omitted.

There was one but it was taken off the market. It's a bit of a sad story because it worked but because of unfounded claims that it had side effects, it lost trust of the public: "In clinical trials involving more than 10,000 people, the vaccine, called LYMErix, was found to confer protective immunity to Borrelia in 76% of adults and 100% of children with only mild or moderate and transient adverse effects. [...] Subs…

Unfounded claims from 100s of people developing imaginary autoimmune disorders? Mind you people are still getting compensated in court for autoimmune disorders arising from the Hep-B vaccine, even though no causal link was found. Just yesterday I had to accompany my sister to the phlebologist, because of severe side-effects from Pfizer, he told us he was seeing troves of patients for similar reasons even though offic…

"These claims were investigated by the FDA and the Centers for Disease Control, which found no connection between the vaccine and the autoimmune complaints."

Re: Valneva and Pfizer announce Phase 2 study for Lyme disease vaccine candidate

#38

Prepare to read the headline "mRNA vaccine trial for " a lot in the future. My guess is that they are going to produce mRNA versions of basically any vaccine (and then some) in the future. The nice thing about the technology seems to be that you only need to exchange the mRNA payload while the surrounding delivery method can be reused. That makes it not only a fast method to create a vaccine but a very convenient way…

Does anyone know why they haven't released a Delta varient vaccine? Is seems that it would just involved we changing the mRNA sequence in a computer at the factor, but I'm really just guessing. Also maybe it is considered a whole new vaccineand needs to go through approval again.

[deleted]

Re: Valneva and Pfizer announce Phase 2 study for Lyme disease vaccine candidate

#39

The first vaccine had a problem where it gave people Lyme every once in a while. My hypothesis is that Lyme disease is an autoimmune disease caused by being exposed too acutely in some way, or for too long. For some people, a tick byte isn’t enough exposure to trigger it. For others, the vaccine is enough. They didn’t catch it early in clinical trials because those people are rare enough to not show up in small studi…

Emphasis should be on tick-bite prevention. I have never had live tick on me and have been literally wallowing on all tick-infested areas on northern hemisphere. They just die. Most probably just drop off, but sometimes there is dead tick only slightly attached. Looks like they die on first drop of blood.
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