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Valneva and Pfizer announce Phase 2 study for Lyme disease vaccine candidate

pfizer.com

11–20 of 271 posts

Re: Valneva and Pfizer announce Phase 2 study for Lyme disease vaccine candidate

#11
post #7

Why is it a vaccine? Are there going to be vaccine for everything in the future?

Vaccines are a very good way to prevent serious disease and may make it possible to eradicate diseases.

The best medical treatment is the one you never have to do.

Re: Valneva and Pfizer announce Phase 2 study for Lyme disease vaccine candidate

#12
Is there a way to compensate people who get injured as part of these trials?

These people..

https://www.youtube.com/watch?v=6mxqC9SiRh8

We hear "Vaccine trials" and handwave this as someone elses problem. But these people, being naive, never thought they would get their lives destroyed. But now it seems that they cannot even get doctors to look into their conditions, and has to live as some sort of societal reject..

Re: Valneva and Pfizer announce Phase 2 study for Lyme disease vaccine candidate

#13

Can anyone give some insight as to why a vaccine hasn't been possible using more traditional technology?

It was, and was about 80% effective IIRC. The problem is most tests look for antibodies. So how do you know you're not in the 20%? I believe many people were still beeing treated regardless of the vaccine. I believe the manufacturer also had some legal issues due to adverse events.

Re: Valneva and Pfizer announce Phase 2 study for Lyme disease vaccine candidate

#14
Prepare to read the headline "mRNA vaccine trial for " a lot in the future. My guess is that they are going to produce mRNA versions of basically any vaccine (and then some) in the future. The nice thing about the technology seems to be that you only need to exchange the mRNA payload while the surrounding delivery method can be reused. That makes it not only a fast method to create a vaccine but a very convenient way as well. Nice side effect might be that for the next pandemic, we might have doses for everyone ready at the moment the trials are done. Take that with a giant grain of salt because I'm not in the industry.

Re: Valneva and Pfizer announce Phase 2 study for Lyme disease vaccine candidate

#15
I posted a comment about the people who are injured in these trials and it got insta-flagged. Here is what I wrote without the link to the video. Just want to see if this gets flagged/removed as well..

>Is there a way to compensate people who get injured as part of these trials? These people..

-- link to video removed --

We hear "Vaccine trials" and handwave this as someone elses problem. But these people, being naive, never thought they would get their lives destroyed. But now it seems that they cannot even get doctors to look into their conditions, and has to live as some sort of societal reject..

Re: Valneva and Pfizer announce Phase 2 study for Lyme disease vaccine candidate

#16
post #7

Why is it a vaccine? Are there going to be vaccine for everything in the future?

A vaccine is an excellent way to prevent an infectious disease. Borelliosis is an infectious disease. Infectious diseases cause human suffering. Vaccinating against as many infectious diseases as possible will reduce a great deal of human suffering.

I guess the real question is why would you not want to reduce human suffering?

Re: Valneva and Pfizer announce Phase 2 study for Lyme disease vaccine candidate

#17
post #3

Ever since I moved to the 'first world' I've been scared of this disease. We don't have it where I come from and the long term effects sound straight up terrible.

Me too, and with Zika and Covid I feel like I've gone back to the dark ages of diseases.

Re: Valneva and Pfizer announce Phase 2 study for Lyme disease vaccine candidate

#18
post #7

Why is it a vaccine? Are there going to be vaccine for everything in the future?

> Are there going to be vaccine for everything in the future?

For a lot of stuff, the answer is probably yes, mRNA based vaccines are a revolutionary game changer - their quick turnaround time means you can actually tailor them to a specific cancer or pathogen the patient has and use the patient's own immune system to fight against the disease. Another advantage of mRNA is that manufacture doesn't depend on chicken eggs which take about six months to produce, are challenging to keep sterile enough and have issues for people with allergies (https://edition.cnn.com/2020/03/27/health/chicken-egg-flu-va...).

However, some viruses like HIV or Influenza mutate so much that it was hard to make effective viruses, we will have to wait and see what the future brings there.

Re: Valneva and Pfizer announce Phase 2 study for Lyme disease vaccine candidate

#20
The first vaccine had a problem where it gave people Lyme every once in a while. My hypothesis is that Lyme disease is an autoimmune disease caused by being exposed too acutely in some way, or for too long. For some people, a tick byte isn’t enough exposure to trigger it. For others, the vaccine is enough. They didn’t catch it early in clinical trials because those people are rare enough to not show up in small studies. So by that logic, the same thing should happen here. Maybe this time it will be a small enough group of people to shove under the rug. There’s no medicine in the world that doesn’t harm people in some capacity.
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