Canada to require vaccinations for air and train passengers

None of what you stated indicates any increased likelihood of ADE. In fact, there are concerns that natural immunity may be more susceptible to antigenic sin, precisely because the immunity is more generic and not focused to the spike protein. This would increase the odds of individuals with just natural immunity of developing a malformed immune response to future variants.

> Hensley worries, though, that people whose immunity to the virus comes from infection, not vaccination, might have more difficulty handling variant viruses because of imprinting effects.

> David Topham, an immunologist at the University of Rochester Medical Center and director of the New York Influenza Center of Excellence, also envisages that possibility.

> He noted that, in the earliest stages of SARS-2 infection, the immune system mounts a response to a portion of the spike protein called S2. Later, the immune system focuses its attention on other parts of the spike, notably the part of the protein that attaches the virus to cells it invades, known as the receptor binding domain.

> It’s not yet known if the early focus on S2 — which doesn’t change much from virus to virus — will blind the immune system to the changes elsewhere in the spike protein, the changes updated vaccines would be trying to teach the immune system to respond to, Topham said.

> Topham doesn’t think this will be a problem in vaccinated people, because of the way the vaccines in use have been designed. The spike proteins they trigger production of appear to hide the S2 region, he said. The immune system can’t fixate on something it doesn’t see. [0]

There’s also doubt as to if COVID even could cause ADE, both because it has yet to be seen across millions of cases, but also because the known mechanisms of ADE don’t apply to Covid [1][2].

Also recent studies have shown that the rate of mutation in a country is inversely correlated with vaccine coverage for Covid. [3]

[0] https://www.statnews.com/2021/04/16/next-generation-covid-19...

[1] https://mobile.twitter.com/macroliter/status/142157887960985...

[2] https://mobile.twitter.com/macroliter/status/142157887960985...

[3] https://mobile.twitter.com/sailorrooscout/status/14254499058...

I'm not sure of their vaccination status, and to be fair my sample size is small because it's been announced recently and there's only so much people you can interact with. That said, we've had a protest here on day 1 and the people I have spoken to are more against a perceived overreach than of the vaccine, although I am young and most non-vaccinated people are in my age group (because of the side effects afai can tell).

I'm weary of polls, especially those paid for by news networks, but even then this was done in may, before the variants became well know/transmission more understood/efficiency more know.

I would think almost certainly. And that's an issue they'll probably have to take up with their embassy if the airline can't make an exception.

Here are some reasons I think this is a very bad idea:

1. The risk/benefit analysis for people under 40 is not as clear as is claimed. "Clot risk to 18-39s from AstraZeneca vaccine is twice as high as Covid death risk, Euro study finds" [0]. That's just clots; not myocarditis, or pericarditis, GBS, CFS, lingering numbness, Bell's palsy, missing periods, and more. Yes, there are some young people who have died with Corona - the vast majority of them had comorbidities.

2. This goes against human rights. Many civil liberties and privacy groups are against "vaccine passports", including the WHO special envoy on COVID-19. If you're response to that is "well I had to take a shot to go to France", well, that's not quite the same as using a train, or keeping your job and career.

3. "But the herd immunity" - No. Herd immunity is not realistically possible with these leaky vaccines. That's even ignoring animal reservoirs and variants; such as could come from deer, mice, rats, cats, dogs, ferrets, mink, monkeys etc - all of which have been shown to be capable of catching Corona and spreading it among themselves.

4. In the past hundred years there are countless examples of governments and pharmaceutical companies performing horrific acts, and covering them up. This goes double for the poor and minorities. Can you really blame native people in Canada for distrusting government?

5. The same mistrust can be understandably applied to the mainstream media who sell us more war, anxiety, fear and distrust every year. Mandating, or "soft" mandating vaccines will mostly achieve riots. It wouldn't surprise me to learn that politicians are heavily invested in tear-gas and riot gear manufacturers.

6. These vaccines are for-profit, yet were provided on condition of full legal indemnity. How can it inspire confidence in people to claim a vaccine is so safe that it can be mandated, while at the same time saying that absolutely no responsibility for any symptom or side-effect whatsoever will be taken by the manufacturers? Pick one! These companies have already made tens of billions of dollars, using research that has taxpayer money behind it on multiple levels.

7. These vaccines are not traditional vaccines. Yes, they have been studied for many years, but also, there is no long term data. The side effects which we know of are poorly understood, i.e., GBS and CFS.

8. Many governments seem to be more interested in bringing in "vaccine passports", and "soft" mandatory vaccinations than actually hiring / training more nurses & building more ICU units. Making good use of subsidised antigen tests, or implementing effective, privacy sensitive contact tracing, seem even lower on the agenda. I don't know how many ICU beds or nurses Canada has hired, or how they are testing, but I suspect there are the same shortcomings there as elsewhere. That's not just bad policy, and bad health management, it's eyebrow raising.

9. Better vaccines - by all accounts, ie Novavax - are on the horizon. Cures and treatments could be coming too. Burning people's career for standing up for their right to determine what concoction is shot directly into their blood right now seems short sighted at best.

[0] - https://www.irishexaminer.com/news/arid-40328123.html *

* Note that Moderna and Pfizer have similar clot profiles to AZ: https://www.euronews.com/next/2021/07/29/astrazeneca-covid-1...