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Pfizer says 2021 Covid-19 vaccine sales to top $33.5 bln, sees need for boosters

reuters.com

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Re: Pfizer says 2021 Covid-19 vaccine sales to top $33.5 bln, sees need for boosters

#151

Post by swader999 »

estebank wrote: post #134
briefcomment wrote: post #125

Earlier quoted context omitted.

Ah yes, as soon as the world stops cultivating peanuts to accommodate my lethal (and heritable) peanut allergy. It should be a no brainer after all, with the nearly infinite other foods we have available as substitutes.

Do you feel like prevalent labeling and stringent segregation policies in food handling to accommodate you aren't equivalent? And if someone's dish sends you into anaphylaxis at a dinner party, the host won't be going "Shouldn't have come then! I refuse to live in peanut-fear!".

A reasonable court would put duty on the guest to inform the host of known allergies.

Re: Pfizer says 2021 Covid-19 vaccine sales to top $33.5 bln, sees need for boosters

#152

Post by vetinari »

mrtesthah wrote: post #121
ScoobleDoodle wrote: post #90

Earlier quoted context omitted.

This vaccine is still unapproved, meaning it's being used experimentally at this point. It has not been approved nor completed normal testing trials. Otherwise it wouldn't have had to receive emergency use authorization. > An Emergency Use Authorization (EUA) is a mechanism to facilitate the availability and use of medical countermeasures, including vaccines, during public health emergencies, such as the current COVI…

> It has not been approved nor completed normal testing trials. Otherwise it wouldn't have had to receive emergency use authorization. That's false. The mere fact that a vaccine is EUA does not mean that it hasn't been tested. The vaccines available under EUA today have gone through exactly the same testing phases as fully FDA-approved ones. The only difference is that the phases were overlapping instead of performed…

They didn't go exactly the same testing phases; the serialization doesn't work like that, you cannot replace time with parallelism (the 9 pregnant women is a suitable analogy).

So, the timeline is:

- Corminaty; currently doing phases 3 and 4; assumed end is december 2023;

- Spikewax: currently doing phases 3 and 4; assumed end is december 2022;

- Vaxzevria: currently doing phases 3 and 4; assumed end is second quarter 2022;

- Janssen: still doing phases 1/2a, 2a, 3; assumed end december 2023;

Re: Pfizer says 2021 Covid-19 vaccine sales to top $33.5 bln, sees need for boosters

#153

Post by vetinari »

Larrikin wrote: post #80
vetinari wrote: post #58

Earlier quoted context omitted.

> Pfizer should be able to profit from the vaccine Government-mandated vaccine from a private supplier. What could possibly go wrong.

So would you rather have your taxes increased so that it is from the government? Would you not be making the same statement if it was a federally funded, just with a word replaced?

> So would you rather have your taxes increased so that it is from the government?

It will increase my taxes anyway; who do you think is paying for all this?

The difference is, that in this way, my taxes pay for privately-held know-how. I want my taxes to pay for public know-how.

Re: Pfizer says 2021 Covid-19 vaccine sales to top $33.5 bln, sees need for boosters

#154

Post by mahogany »

makomk wrote: post #118
joshuamorton wrote: post #99

Earlier quoted context omitted.

There are some people for whom the vaccine will not be effective (those who are already immunocompromised for example, or people with certain allergies to vaccine ingredients). > But for a young person with no co-morbidities, that chance is still basically 0%. Having long term side effects doesn't round to zero, even for young healthy people. And vaccine side effects do.

Historically speaking, countries have refrained from forcing even medical workers and people caring for the elderly to get flu vaccines, even though this argument - that there are some people for whom the vaccine will not be effective - is even more true of that (in fact, as I understand it some studies suggest the flu vaccine might be basically ineffective at preventing serious complications and death in those at ri…

> As far as I can tell, the only reason to treat Covid differently basically boils down to partisan politics...

A difference is that COVID is much deadlier, no?

Re: Pfizer says 2021 Covid-19 vaccine sales to top $33.5 bln, sees need for boosters

#155

Post by _-david-_ »

joshuamorton wrote: post #109
_-david-_ wrote: post #98

Earlier quoted context omitted.

The measles vaccine has been around for decades. There are plenty of long term studies on the efficacy and saftey. How many long term studies have there been on any of the covid vaccines?

mRNA vaccines have been researched for decades, and the only really novel part of the covid vaccine is the particular protein, which will also be present in a natural infection. So if you trust the decades of mRNA vaccine research, you should consider the vaccine strictly safer than covid, as getting the disease will expose you to everything the vaccine exposes you to.

Do you believe there doesn't need to be long term studies of traditional vaccines? There have been decades of research into them as well.

I believe both mrna and traditional vaccines are safer than covid. I just don't like to take vaccines or medication without longer results than a year. I also agree mRNA vaccines shouldn't have any long term negative effects, but I tend to take the position when in doubt don't take an action.

If in 5 years there hasn't been any widespread negative effects I will probably take it.

Re: Pfizer says 2021 Covid-19 vaccine sales to top $33.5 bln, sees need for boosters

#156

Post by sudosysgen »

makomk wrote: post #118
joshuamorton wrote: post #99

Earlier quoted context omitted.

There are some people for whom the vaccine will not be effective (those who are already immunocompromised for example, or people with certain allergies to vaccine ingredients). > But for a young person with no co-morbidities, that chance is still basically 0%. Having long term side effects doesn't round to zero, even for young healthy people. And vaccine side effects do.

Historically speaking, countries have refrained from forcing even medical workers and people caring for the elderly to get flu vaccines, even though this argument - that there are some people for whom the vaccine will not be effective - is even more true of that (in fact, as I understand it some studies suggest the flu vaccine might be basically ineffective at preventing serious complications and death in those at ri…

Of course not. Most countries have mandated vaccines for HCW.

The reason the flu vaccine isn't one of them is because it's not that effective to begin with and you have to take it every year. It's not effective enough to really stop an epidemic, so instead vaccinating patients is the main thrust instead of HCW, because the overall impact will be fairly low.

Re: Pfizer says 2021 Covid-19 vaccine sales to top $33.5 bln, sees need for boosters

#157

Post by swader999 »

myko wrote: post #130
mnowicki wrote: post #113

Earlier quoted context omitted.

again, I got the vaccine and I'm not anti-vax, but why are people getting downvoted for making valid points just because they aren't following the popular narrative. Did this website become reddit? You can acknowledge someone made a decent point and incorporate it into your own views while still getting & encouraging vaccines - engaging in honest discussion will do more to prevent creating more anti-vaxxers than igno…

I imagine folks are taking issue with calling anti-vaxxers a scapegoat when in reality the anti-vaxx ideology is the main driver of hospitalizations and deaths from COVID-19 in the USA today.

Comorbidities?

Re: Pfizer says 2021 Covid-19 vaccine sales to top $33.5 bln, sees need for boosters

#158

Post by sudosysgen »

mrhands69 wrote: post #129
joshuamorton wrote: post #110

Earlier quoted context omitted.

You'll, of course, cite a source? There aren't actually any virus particles in the mRNA vaccines, so there's no biological mechanism for that to happen.

I can get a source in a bit. IIRC it was the spike protein that causes some (still unknown) response from the human body. The mRNA vaccine elicit a response from the immune system to reproduce the spike protein.

We have no idea that the spike protein causes long covid. It's much more likely that damage from the viral infection and immune response is at least an equal cause.

Beyond that, the virus causes orders of magnitude more spike protein response, so even if that was true, which it probably isn't, then it is still very unlikely that the vaccine could cause long-covid.

Also, all vaccines introduce spike proteins in the body, not just mRNA vaccines.

Re: Pfizer says 2021 Covid-19 vaccine sales to top $33.5 bln, sees need for boosters

#159

Post by swader999 »

e40 wrote: post #30
beachy wrote: post #17

Anti-vaxxers are setting the stage for enormous profits for big pharma by creating the conditions for breeding new variants that will require more big pharma to combat them. I feel my grandkids will grow up in a world quite different from mine, where travel and experiences will be gated and limited by fear of contagious disease. That sucks and didn't need to happen. Thought experiment for anti-vaxxers - what if there…

They’d probably pivot to say that’s the risk of a free life. Live free or die is the mantra of many of them. Of course it’s their life which is free, not the people they infect. I loved your hypothetical device.

Everyone is free to get the vaccine and the risk reward profile varies between ages.

My body my choice but not for experimental vaccines?

Fauci admitted yesterday infection and transmission are still possible in vaccinated. CDC renewed their indoor mask guidance because this is now evident.

So if both groups can transmit, what does vax status matter personally to you? They aren't even a large enough size to overwhelm health care in most areas that have access to the vaccine.

Re: Pfizer says 2021 Covid-19 vaccine sales to top $33.5 bln, sees need for boosters

#160

Post by swader999 »

notheretoo wrote: post #38
beachy wrote: post #17

Anti-vaxxers are setting the stage for enormous profits for big pharma by creating the conditions for breeding new variants that will require more big pharma to combat them. I feel my grandkids will grow up in a world quite different from mine, where travel and experiences will be gated and limited by fear of contagious disease. That sucks and didn't need to happen. Thought experiment for anti-vaxxers - what if there…

You’re right - this gated world didn’t need to happen. Sure would have been nice if American scenarists and eco health didn’t continue gain of function research after it was outlawed in the us. So uh what about this? https://wwwnc.cdc.gov/eid/article/27/10/21-1427_article If it’s true the vax causes antibody dependent enhancement and that YOU, as the individual who took the experimental therapy, is producing higher v…

I don't think this study does or can claim ADE. It's too bad they didn't report on blood based viral loads from titer samples.

This observation is very interesting, albeit a small sample: "Attack rate was 0/6 among persons with a previous history of COVID-19"

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