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Pfizer says 2021 Covid-19 vaccine sales to top $33.5 bln, sees need for boosters

reuters.com

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Re: Pfizer says 2021 Covid-19 vaccine sales to top $33.5 bln, sees need for boosters

#91

Post by mrtesthah »

swader999 wrote: post #68
mrtesthah wrote: post #24

Earlier quoted context omitted.

He's referring to replication in the nasal passage[1], which was already expected[2] and has nothing to do with overall viral titers in the blood stream nor with ADE. ADE would have been detected long before the first trials from last year ended (see tylerhou's comment). "As the Associated Press notes, Walensky cited data from the last few days, still unpublished, taken from 100 samples from vaccinated and unvaccinat…

ADE may only occur when immunity wanes though and we may just be at the start of this period. Also ADE can occur for some variants but not necessarily all. And we would hope they would share data on blood titers very soon between these groups because yes, blood titers are more accurate and definitive.

If you are aware that the metric here is nasal replication then you should correct your original comment containing unfounded speculation about ADE.

Re: Pfizer says 2021 Covid-19 vaccine sales to top $33.5 bln, sees need for boosters

#92

Post by programmarchy »

A very interesting observation [1] was made by Dr John Campbell who noticed a difference between vaccine efficacy in Israel vs UK. In Israel, the doses were spaced 2-3 weeks apart, and the protection against transmissibility has dropped off significantly more than in the UK, where doses were spaced further apart, sometimes over 10 weeks between the first and second dose. His hypothesis was that a longer duration between doses may actually improve long term efficacy.

[1] https://youtu.be/wNbs4LCgrcY?t=464

Re: Pfizer says 2021 Covid-19 vaccine sales to top $33.5 bln, sees need for boosters

#93

Post by seanicus »

briefcomment wrote: post #57
beachy wrote: post #17

Anti-vaxxers are setting the stage for enormous profits for big pharma by creating the conditions for breeding new variants that will require more big pharma to combat them. I feel my grandkids will grow up in a world quite different from mine, where travel and experiences will be gated and limited by fear of contagious disease. That sucks and didn't need to happen. Thought experiment for anti-vaxxers - what if there…

What if we built a device that could trace a particle from your car's exhaust and could tell you if that particle lodged itself in someone's lung at just the right moment to cause a stroke? Or how about a device that could trace the germs from when you skipped washing your hands for at least 20 seconds with a lather because you were late to your 1 on 1 with your boss, which then caused your elderly neighbor to catch…

You should write a whole whataboutism novel. It'd kill on facebook.

Re: Pfizer says 2021 Covid-19 vaccine sales to top $33.5 bln, sees need for boosters

#95

Post by hdjjhhvvhga »

beebmam wrote: post #76
Panther34543 wrote: post #11

In summary: A.) Pfizer is raking in over $33 billion from vaccine sales. B.) Due to the PREP Act, they are completely immune from lawsuits arising from any form of complications arising from those vaccines. C.) If you don't take this vaccine, you may lose your job[0]. D.) If you don't take this vaccine, you may be barred from normal everyday social activities[1][2]. I can't be the only one who is incredibly uncomfort…

If I'm forced to work in an office, and some of my colleagues don't want to get vaccinated or tested regularly, I WANT them to get fired. It is a workplace safety issue for everyone forced to work in an enclosed area.

> If I'm forced

I agree with your sentiment, but it is not your coworkers who decided that now it's time to force everyone back into the office.

Re: Pfizer says 2021 Covid-19 vaccine sales to top $33.5 bln, sees need for boosters

#96

Post by sudosysgen »

briefcomment wrote: post #73
mint2 wrote: post #37

Earlier quoted context omitted.

Given that: A. Pfizer isn’t the only vaccine option. B. If one doesn’t take the vaccine, one’s chances of dying or being disabled for years or permanently are much higher. C. If one doesn’t take the vaccine there is a significant chance they give the virus to someone else, killing them. I think it’s the best option out of all non-great options to mandate vaccines in order to participate in crowded settings. It’s a ma…

> B. If one doesn’t take the vaccine, one’s chances of dying or being disabled for years or permanently are much higher. But for a young person with no co-morbidities, that chance is still basically 0%. > C. If one doesn’t take the vaccine there is a significant chance they give the virus to someone else, killing them. Even if others have taken the vaccine themselves? Either that particular risk is negligible if the…

Only for you. The argument above was from civic responsibility, by being in crowded environments while unvaccinated you risk the lives of others.

Also, the chance of being disabled for a long while if you are young without comorbidity is far from 0%. It is quite significant, certainly above 0.5%.

Re: Pfizer says 2021 Covid-19 vaccine sales to top $33.5 bln, sees need for boosters

#97

Post by incrudible »

mint2 wrote: post #37
Panther34543 wrote: post #11

In summary: A.) Pfizer is raking in over $33 billion from vaccine sales. B.) Due to the PREP Act, they are completely immune from lawsuits arising from any form of complications arising from those vaccines. C.) If you don't take this vaccine, you may lose your job[0]. D.) If you don't take this vaccine, you may be barred from normal everyday social activities[1][2]. I can't be the only one who is incredibly uncomfort…

Given that: A. Pfizer isn’t the only vaccine option. B. If one doesn’t take the vaccine, one’s chances of dying or being disabled for years or permanently are much higher. C. If one doesn’t take the vaccine there is a significant chance they give the virus to someone else, killing them. I think it’s the best option out of all non-great options to mandate vaccines in order to participate in crowded settings. It’s a ma…

Pfizer and Moderna have similar risk profiles, everything else seems to be much worse. Argument B is highly subjective and I would argue that "the data isn't there" for the young and healthy parts of the population. Despite being "safe and effective" by the standards of medicine, a Sars-COV2 vaccination also carries a non-zero risk of disability and death. Argument C doesn't really cut it, because "someone else" should've gotten the vaccine themselves, if they're at risk.

It's now becoming obvious that vaccinated individuals can still be infected and can spread the infection as well. At the same time, mortality is greatly diminished. At that point, we have a vague and unspecific reduction of an already modest risk. This is insufficient to make a "civic responsibility" argument. By the same token, I could argue people should not drive cars as a matter of civic responsibility, because that carries a non-zero risk of killing a pedestrian.

Re: Pfizer says 2021 Covid-19 vaccine sales to top $33.5 bln, sees need for boosters

#98

Post by _-david-_ »

b0sk wrote: post #65
clairity wrote: post #35

Earlier quoted context omitted.

> "I can't be the only one who is incredibly uncomfortable about society going down this path." it's dystopian. this is power that won't be reliquished by either major party, just like 9/11 surveillance and security theater. unlike some of currently fashionable political impetuses, this one is worth actively resisting, to keep federal powers in check.

lol. vaccination is the law. you guys can't spread measles anymore and thank god for that.

The measles vaccine has been around for decades. There are plenty of long term studies on the efficacy and saftey. How many long term studies have there been on any of the covid vaccines?

Re: Pfizer says 2021 Covid-19 vaccine sales to top $33.5 bln, sees need for boosters

#99

Post by joshuamorton »

briefcomment wrote: post #73
mint2 wrote: post #37

Earlier quoted context omitted.

Given that: A. Pfizer isn’t the only vaccine option. B. If one doesn’t take the vaccine, one’s chances of dying or being disabled for years or permanently are much higher. C. If one doesn’t take the vaccine there is a significant chance they give the virus to someone else, killing them. I think it’s the best option out of all non-great options to mandate vaccines in order to participate in crowded settings. It’s a ma…

> B. If one doesn’t take the vaccine, one’s chances of dying or being disabled for years or permanently are much higher. But for a young person with no co-morbidities, that chance is still basically 0%. > C. If one doesn’t take the vaccine there is a significant chance they give the virus to someone else, killing them. Even if others have taken the vaccine themselves? Either that particular risk is negligible if the…

There are some people for whom the vaccine will not be effective (those who are already immunocompromised for example, or people with certain allergies to vaccine ingredients).

> But for a young person with no co-morbidities, that chance is still basically 0%.

Having long term side effects doesn't round to zero, even for young healthy people. And vaccine side effects do.

Re: Pfizer says 2021 Covid-19 vaccine sales to top $33.5 bln, sees need for boosters

#100

Post by gradys »

briefcomment wrote: post #73
mint2 wrote: post #37

Earlier quoted context omitted.

Given that: A. Pfizer isn’t the only vaccine option. B. If one doesn’t take the vaccine, one’s chances of dying or being disabled for years or permanently are much higher. C. If one doesn’t take the vaccine there is a significant chance they give the virus to someone else, killing them. I think it’s the best option out of all non-great options to mandate vaccines in order to participate in crowded settings. It’s a ma…

> B. If one doesn’t take the vaccine, one’s chances of dying or being disabled for years or permanently are much higher. But for a young person with no co-morbidities, that chance is still basically 0%. > C. If one doesn’t take the vaccine there is a significant chance they give the virus to someone else, killing them. Even if others have taken the vaccine themselves? Either that particular risk is negligible if the…

On the last point:

1) The vaccine isn't perfect, and herd immunity nonlinearly reduces the risk of everyone including the vaccinated from getting it.

2) Unvaccinated people, who make up the vast majority of the cases, create an environment for the virus to evolve within, possibly mutating into a form that is more dangerous to everyone, including the vaccinated

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