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SARS-CoV-2 Gamma variant infected 16 fully Pfizer vaccinated Guiana gold miners

wwwnc.cdc.gov

121–130 of 292 posts

Re: SARS-CoV-2 Gamma variant infected 16 fully Pfizer vaccinated Guiana gold miners

#121
post #112

As other commenters have noted, this case study further supports the widespread observations that COVID-19 vaccines reduce the chance of severe (symptomatic) illness but do not necessarily prevent infection and transmission. The authors of this study conjecture that the unvaccinated asymptomatic “patient 40” may have been the source of the infections seen in the other fully vaccinated patients - however this was a mi…

> imperfect vaccines can cause selective pressure which enhances the fitness of highly virulent pathogens I've wondered this ever since the UK changed it's approach and now that we've got to a state where there is pretty much no restrictions. I think scientists around the world also have this concern with the UK's approach

Why would I want to vaccinate if I'm still going to get restricted?

I mean the whole deal here was that if we got vaccinated we'd be back to normal life. If that wasn't the case they should've been sincere up front and most of us wouldn't have gotten vaccinated.

Re: SARS-CoV-2 Gamma variant infected 16 fully Pfizer vaccinated Guiana gold miners

#122
post #99

Earlier quoted context omitted.

So does this mean we made this pandemic worse than the one from 1918 when we didn't have a vaccine?

This is very likely. And has already been said by various critics already months ago. But these people were silenced or ridiculed, because it apparently was already decided the vaccines need to be sold.

Completely untrue. The reservoir of selfish unvaccinated individuals is what is providing a place for Covid to hide and mutate. Vax critics were silenced and ridiculed because they are dangerous deceivers who need to be called out and held to account for the consequences of their lies.

Re: SARS-CoV-2 Gamma variant infected 16 fully Pfizer vaccinated Guiana gold miners

#123

Earlier quoted context omitted.

> imperfect vaccines can cause selective pressure which enhances the fitness of highly virulent pathogens The number of ways in which we undertaking a natural experiment in viral evolution has been top-of-mind for me as well. But the greater issue in my view is not that the vaccines are imperfect. All vaccines are somewhat imperfect. On its own, I the mRNA vaccines were probably entirely adequate. The problem is that…

In addition, the vaccines currently in use -- at least in the West -- are either mRNA or vector vaccines containing only parts of the virus (as far as I know only the spike protein from the virus's surface). I would expect them to result in a more specific immunity which is easier for the virus to circumvent, my mutating only its spike protein. Conventional vaccines however, which are more prevalent in the developing…

My guess is that nobody really knows the answer to that question. It's also entirely plausible that the only way to have true sterilizing immunity to COVID is to have antibodies to the spike protein. shrugs

Re: SARS-CoV-2 Gamma variant infected 16 fully Pfizer vaccinated Guiana gold miners

#124
post #3

"No clinically severe COVID-19 (1) was observed, and no patient was hospitalized" In other words, this case study is a relatively ordinary result in line with what we know: that the major COVID-19 vaccines greatly reduce the chance of severe illness but leave nontrivial chance of infection and transmission.

What’s more interesting is that 0/6 of the miners who had natural immunity were re-infected. That points to natural immunity preventing spread. The fact that vaccinated individuals don’t stop transmission means that there is no “public good” from getting vaccinated, it’s solely for personal benefit. Vaccine mandates or checking for vaccination status are pointless because of this.

> there is no “public good” from getting vaccinated, it’s solely for personal benefit.

Even if your other claims were correct, the conclusion still wouldn’t be. Severe cases put massive strain on the health care system.

Re: SARS-CoV-2 Gamma variant infected 16 fully Pfizer vaccinated Guiana gold miners

#125

there's a gamma now? nature is sure on it version control game

There is even more and it's not nature, it's WHO (and representatives from GISAID, Nextstrain, Pango).

Currently designated Variants of Concern: Alpha, Beta, Gamma, Delta

Currently designated Variants of Interest: Eta, Iota, Kappa, Lambda

https://www.who.int/en/activities/tracking-SARS-CoV-2-varian...

Re: SARS-CoV-2 Gamma variant infected 16 fully Pfizer vaccinated Guiana gold miners

#126
post #87

Earlier quoted context omitted.

I got it, and it was annoying, sure, but I had influenza A in the past and boy, was that REALLY bad. I would be totally fine if we get to a point where we consider Covid to be like an endemic seasonal flu for the vaccinated, because I can’t see many ways out otherwise

I think what a lot of people call the flu is actually "the sniffles" which desensitizes people to the danger. Influenza like you had is really, really bad. It takes weeks to recover and the first 1 or 2 weeks are hell.

Yes, that is correct. I believe the difference is that most of us were exposed to the flu when we were younger, building immunity to the strains that are seasonal.

This is not the case for new strains. There are reports from the 1918 influenza strain that it killed young people over night: Folks went to bed with fever and didn't wake up the next day.

If you had the flu or know somebody who had, it's no joke.

Re: SARS-CoV-2 Gamma variant infected 16 fully Pfizer vaccinated Guiana gold miners

#127

Earlier quoted context omitted.

I had the virus and it was slightly inconvenient, had a slight fever, cough and shortness of breath. Strangly my wife had different symptoms to me, no fever and vomiting. Lasted around 10 days with no lingering symptoms. I think the fever is important because my wife got reinfected but I did not.

Glad you're ok, but I'm surprised you describe SOB as a slight inconvenience. In general, SOB is a pretty bad sign-- you're having trouble getting the one thing you'll die fastest without. Sure, you can put up with temporary mild SOB if you know it's going to stay mild, but not everyone can know that :/

Thanks, I realize I was lucky, it is a wildly unpredictable virus and I am not trying to minimize the possible outcomes.

Re: SARS-CoV-2 Gamma variant infected 16 fully Pfizer vaccinated Guiana gold miners

#128
post #8

Earlier quoted context omitted.

That is an incredible leap.

Nope, globally we know that re-infection rarely occurs after being infected. This study shows a 60% attack rate for fully vaccinated miners, which is horrendous. The whole point of this study is that vaccination does not stop transmission of the virus. To quote the study: In conclusion, we describe a VOC Gamma COVID-19 outbreak with a strikingly high attack rate among persons fully vaccinated with BNT162b2 vaccine.[……

The mine in question had 44 employees. The sample size is thus a bit small, the mine is probably not well-ventilated, and the working conditions are not good for health in general. Of course, it's bound to happen that eventually a COVID variant emerges against which a booster shot becomes required,so this might or might not hint at something greater.

Re: SARS-CoV-2 Gamma variant infected 16 fully Pfizer vaccinated Guiana gold miners

#129

If someone can check my math, this seems like a perfect opportunity to do a statistical test. Sample sizes are too small to say that there is a difference between previous infection and no previous infection. Given the contingency table: No prior inf. Prior inf. Infected 3 0 Uninfect 4 6 A Fisher Exact Test yields a p value of 0.1923. So there is not evidence that previously infected people are safe. Similarly, if we…

I think the "4" should be changed to a "1" yielding p = 0.0333. 4 is the total number of unvaccinated miners without prior infection.

Re: SARS-CoV-2 Gamma variant infected 16 fully Pfizer vaccinated Guiana gold miners

#130

Earlier quoted context omitted.

My understanding is that there is very little evidence of vaccinated individuals actually transmitting the original ("wild-type") virus, or even the Alpha variant (obviously, Delta/Gamma are potentially different beasts). This was why we in the United States dropped mask mandates for vaccinated individuals. I don't know why the narrative always reverts to "oh, the vaccines just decrease symptoms", a statement unsuppo…

The amount of abstract certainty present in this comment is truly astonishing. Please just cite the RCT on this.

https://pubmed.ncbi.nlm.nih.gov/33964222/
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