351–360 of 454 posts
If you have a C/C pair at AKT1, your risk of developing schizophrenia jumps from slightly-below-average if you don't smoke marijuana, to over 7x average if you smoke every day [0].
If you've done 23andMe, you can check your own genotype for this risk.
[0]: https://www.drugabuse.gov/publications/research-reports/mari...
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"One became extremely paranoid to the point he was unable to maintain relationships with the people around him" I would bet you anything that this person was using a high-potency grade of cannabis and/or smoking a lot of it. If they just used a little bit of a low-potency strain it's unlikely they would have suffered from paranoia. "several others became extremely unpleasant and irritable when they weren't high on th…
The reality is that many people in legal weed states consume cannabis via edibles these days. Manufacturing techniques have greatly improved in the past couple of years and they aren't nearly as gross tasting as they used to be, often they have almost no weed taste at all. Edibles are usually highly opaque in terms of the strains used and tend to contain at least 5mg THC per dose, sometimes 10, and that's if you trus…
We know when using a psychedelic dose, set, and setting become critical.
People taking a strong dose of a psychedelic and expecting it to be no more than a regular pot high might be in for a rude awakening, especially if they treat it casually instead of with great respect, take it in inappropriate circumstances (like at parties or clubs full of people they don't know or trust), etc.
It's no wonder that many people suffer from paranoia and other adverse effects from casual use of edibles. They should really be treating a strong dose of edible cannabis like they do a strong dose of LSD.
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I think the increase in cases is more likely to be explained by a number of factors: 1. THC concentrations have increased which usually means there is less CBD. 2. Legalization probably increased casual use. 3. People who suffer from schizophrenia are simply more likely to be diagnosed for whatever reason. The sum of these three things could easily account for a significant increase in diagnosis. Sometimes increases…
The high THC and lack of CBD in today's strains is concerning (to me) honestly. I'm worried that a lot of the data we've seen in the past about chronic cannabis use being relatively safe may not apply when THC/CBD ratios approach 50:1, since CBD and other cannabinoids counter act some of THCs effects.
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I am sorry to say that you are most likely right. My father is[0] a psychiatrist in big psychiatric hospital in France (1500 beds, only psychiatry, nothing else) and he told me again and again that he was against the legalisation of marijuana because of this. The problem is that once you trigger schizophrenia you need to live with it, all your life... Note that he told me so, even if his work during the last 15 years…
Same experience with a (art) therapist in a mental hospital (less than 1500 beds). Very persistent in asserting that weed causes some people to end up there. I don't think it's a good argument against legalization. We don't ban alcohol, because there are alcoholics. I think it would be smarter to regulate the recreational drug industry and use its taxes to fund relevant education, research and mental health programme…
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Weed actually contains anti-inflammatory and anti-carcinogenic components, that's why people say it is healthier then other plants when inhaled. I'm not making this up, please look for it yourself if you care for the full picture and are genuinely interested as to why people say that.
This literally reads like a stoner in denial
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Sort of sounds like me a decade ago. If you find yourself still doing the same job in a decade, I think you'll know why. Tech jobs are very compatible with weed. The sort of tactical, short term thinking you need to apply current knowledge to problems works well. It's great for crafting clever, short-term solutions and hacking your way through things. If that's all you ever want to be, smoke weed everyday man, why no…
I am not a grower and have moved up consistently in my career over the last decade from IT helpdesk to devops lead, with a company that’s profitable, and currently many rounds of demos deep with two very big businesses I can’t even tell you what industry we’re in that’s how new and weird this tech is. Sounds like you made being high your identity. To me it’s like coffee (which I drink sparingly as caffeine messes me…
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According to studies, cannabis potency has indeed increasedi n Europe in the last few decades. See An overview of cannabis potency in Europe ( https://www.emcdda.europa.eu/publications/insights/cannabis-... ) and Increasing potency and price of cannabis in Europe, 2006–16 ( https://onlinelibrary.wiley.com/doi/10.1111/add.14525 ). From the abstract of the latter study: "Resin potency increased from a mean [95% confide…
Anecdotally, I've heard in the 60s and 70s generally people would just smoke a lot more weed in a single sitting than today. Several joints to a person of harsh brick weed vs. half of one with decent modern weed, for example.
I have enjoyed smoking Cannabis for decades, but a recent bought of financial difficulty coupled with a desire to get programming last week has shown some teeth on the cute little bubbly image of Cannabis in my mind. I started smoking more (due to stress) and trying to complete a new project (financial difficulty) and it was just a nightmare. It's noticeably more difficult to concentrate and retain new information wh…
I’m not in a financially stressful situation, but have been under a lot of performance stress in recent jobs. I found the best routine for myself was meetings during the day + whatever coding I could fit.
Where it gets interesting is at night, I would have a Coke Zero for a small caffeine kick and vape a bit of weed - not a lot - and put on some tunes. Then I’d be totally in the zone and code several day’s worth of work in a night. Sometimes even more.
I was praised for high productivity, and got a lot of work done. I don’t do it as often now, trying to maximize my sleep and my current work has more inter-team tension... but overall I get less work done now.
It definitely was a cheat code to enter the zone for a good 4-6 hours at night, and helped me perform at a higher level than I normally would.
Worth noting I wasn’t avoiding anything or using it as a tool for comfort. I think that can blur the line into an addiction or avoidance mechanism that can be harmful.