Earlier quoted context omitted.
I think you're overlooking the most important scenario: mass production of it in a factory setting.
And just handling/storage. Things that are flammable or explosive have more-stringent requirements. A familiar example: one should take much greater care when storing rubbing alcohol (or Bacardi 151 or vodka) than wine. One will magnify a house-fire. The other will help to douse a flame.
Temozolomide Is Explosive
31–40 of 128 posts
Re: Temozolomide Is Explosive
#32Re: Temozolomide Is Explosive
#33Earlier quoted context omitted.
Nitrogen-Nitrogen bonds inside larger molecules are never quite stable because 1) nitrogen “wants” to form stable di-nitrogen (N2) molecules containing a very stable triple bond (an exothermic reaction) and 2) the result of such decompositions is nitrogen gas increasing the amount of entropy released (due to more molecules being created). Reactions are driven both by the amount of heat released (enthalpy) and the amo…
Does the same apply to oxygen? Since it also likes to be in a diatomic form.
Re: Temozolomide Is Explosive
#34Re: Temozolomide Is Explosive
#35Re: Temozolomide Is Explosive
#36I mean in fairness we still use nitroglycerine for some heart ailments, so chemo - a field filled with horrific chemicals - having an explosive shouldn't be too surprising.
Re: Temozolomide Is Explosive
#37"What they found was rapid onset of decomposition at 170 degrees" So this seems to be more about people in a lab situation rather than it being so unstable it reacting sitting in someone's hot car. Suspecting it to react at 212 and finding it reacting at 170 could ruin a lab tech's day to be sure. Those are the jobs that sound fun "for the science" lets see what happens when...
Re: Temozolomide Is Explosive
#38Reminds me of how DNP, a chemical used for creating explosives, has been used as a weight-loss drug. It's surprisingly effective, but overdosing on it will result in a long, hot, agonizing death.
Interestingly, babies use a controlled variant of this mechanism to help maintain their body temperature thanks to their brown fat tissue. It makes babies look cute and keep warm. :)
Re: Temozolomide Is Explosive
#39Chemotherapy is basically cave man medicine. That a therapeutic drug is explosive only adds to that sentiment. The idea that we'll basically poison you just up to a point that's nearly fatal in order to kill the cancer is such a terrible way to treat someone. Now I'm not saying don't ever do it -- unfortunately that's where we're at in 2021. It's just kind of unbelievable that cancer remains so elusive that we're sti…
Some years ago, a close friend died of a relatively rare and aggressive form of cancer. Among my roles was running interference against those who were pitching various miracle cures, with that tired old scam laetril playing a significant role.
In the decades since, I've watched developments in the science and development, as well as traced the history. It turns out that the treatment received a few decades ago was little changed from that of the 1960s, and has progressed little since. Genetic sequencing identified the affected chromosome of the triggering mutation in the 1980s, and we now know the specific codons involved. There remains no cure.
Five year survival remains about 20%. Laetril is still a fraud. And several of the other patients we came to know during the course of my friend's treatment have died since of conditions related to the treatment itself, though yes, they did buy another 10--20 years.
Cancer is brutal.
I will note: "cancer" is a symptom cluster manifested by malignant growth, and virtually always due to genetic mutation within the affected cells (I'd say "always" though I'm not completely sure of that). The specific triggers, and the possibilities for cure, vary tremendously. Some bladder cancers are virtually entirely treatable by, of all things, tuberculosis baccili. Skin cancers if caught early pose little risk. Others are tremendously aggressive, and an online friend's posts progressed from announcing their partner's diagnosis with liver cancer to the partner's death over the course of less than two months.
Broad-brush statements are virtually always false.
Re: Temozolomide Is Explosive
#40Chemotherapy is basically cave man medicine. That a therapeutic drug is explosive only adds to that sentiment. The idea that we'll basically poison you just up to a point that's nearly fatal in order to kill the cancer is such a terrible way to treat someone. Now I'm not saying don't ever do it -- unfortunately that's where we're at in 2021. It's just kind of unbelievable that cancer remains so elusive that we're sti…