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Biohackers take aim at big pharma’s stranglehold on insulin

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321–330 of 392 posts

Re: Biohackers take aim at big pharma’s stranglehold on insulin

#321
post #305

I've never quite understood why there's no clandestine insulin market. You're working up GMO yeast metabolites, that's not exactly a new idea.

Why take the risk in selling something like that? You're never going to be able to make money on it. Or did you mean people should just make their own?

Re: Biohackers take aim at big pharma’s stranglehold on insulin

#322
post #300

Earlier quoted context omitted.

Not actually the question since countries with modern healthcare systems provide all types of insulin at an average cost per unit that is roughly 1/10th to 1/20th the cost in the United States (cheap vs. expensive is an over simplification).

No, it is the question because countries with public health systems often don’t pay for the latest generation of drugs, since they don’t feel the extra cost is worth the benefit.

It's still the wrong question to ask.

We should ask what are the outcomes that these systems produce, not how new the drugs are.

A cutting-edge healthcare system plagued by inequality and extreme costs can produce worse results than a more efficient healthcare system which is not as high-tech.

Re: Biohackers take aim at big pharma’s stranglehold on insulin

#323

Every time this stuff comes up it feels like we focus on the politics and not the people with diabetes. If you or your kid or your friends have Type 1 and are struggling to make your insulin out of pockets please, please, please call the Eli Lily hotline and get the copay card. They've dropped the monthly cost for Humalog to $35. Don't ration. Work the system. https://www.humalog.com/savings-support

> please, please, please call the Eli Lily hotline and get the copay card. While this is a great thing, it's also necessary that you be prepared to fork over personal data - especially proof of income - and otherwise do whatever is required to prove that you are (un?)worthy enough as with any similar medical financial aid program. https://www.lillycares.com/assets/pdf/lilly_cares_applicatio...

Wow nitpicking much?

Re: Biohackers take aim at big pharma’s stranglehold on insulin

#324
post #305

I've never quite understood why there's no clandestine insulin market. You're working up GMO yeast metabolites, that's not exactly a new idea.

There is, it just isn’t clandestinely manufactured insulin.

https://medicalxpress.com/news/2020-01-diabetics-black-canad...

Re: Biohackers take aim at big pharma’s stranglehold on insulin

#325

Every time this stuff comes up it feels like we focus on the politics and not the people with diabetes. If you or your kid or your friends have Type 1 and are struggling to make your insulin out of pockets please, please, please call the Eli Lily hotline and get the copay card. They've dropped the monthly cost for Humalog to $35. Don't ration. Work the system. https://www.humalog.com/savings-support

> please, please, please call the Eli Lily hotline and get the copay card. While this is a great thing, it's also necessary that you be prepared to fork over personal data - especially proof of income - and otherwise do whatever is required to prove that you are (un?)worthy enough as with any similar medical financial aid program. https://www.lillycares.com/assets/pdf/lilly_cares_applicatio...

Its not a financial aid program, its a market segmentation program.

Re: Biohackers take aim at big pharma’s stranglehold on insulin

#326

Earlier quoted context omitted.

I felt the same for a while too, but then I met someone that happened to work for child services. These are some caring and empathetic people working for peanuts and they aren’t really treated well by anyone, management and clients alike. This person in particular hated the work but didn’t want to quit for fear of letting their clients (children) down. People blame bureaucracy, and maybe there’s some truth there, but…

It's real easy to become a jaded clock puncher when you're a social worker on a six person team that can barely eek out three people's worth of work because three of the people are deadbeats who's only qualifications are an ability to deposit paychecks and knowing someone who was owed a favor by a politician or appointed high level bureaucrat. The one party states have it the worst because the "next guy's cronies" ca…

Ah yes. The new administration's "house cleaning."

Better known by the people who actually work there as, "Shoving a bunch of people and papers around to show you're changing things, with no plan, strategy, or even background information to support a single thing."

If you think alternating parties solves the problems, you have another think coming your way!

Re: Biohackers take aim at big pharma’s stranglehold on insulin

#327
post #203
post #78

Earlier quoted context omitted.

Every drug company gives away their drugs for free to people who can't afford it in the US. It's sad that not enough people take advantage of patient assistance programs.

I'm curious, but what does "can't pay" mean? Does it mean the drug cost 100%+ of your income? 10% of your income?

It means “the manufacturer realizes they won’t get the price they charge from other channels from you, so is willing to settle for the PR and tax benefits (and whatever residual cost is still charged) rather than nothing.

Re: Biohackers take aim at big pharma’s stranglehold on insulin

#328
post #303
post #279

Earlier quoted context omitted.

Hi, I am one of the scientists working on the project. We had a lot of discussion on the project about defensive strategies to avoid any issue, since we are dealing with a massive industry. We don't have a definitive protocol yet, so this is why it is not publish. But if you want more details, I would be happy to answer your questions.

I've seen a lot of projects like yours with the purest of goals never get past this stage because, simply, nobody makes the first move. It's almost like the attention gets in the way of publication. Either that, or there was never anything there, and it was just good PR from the beginning. Your project is too damn important to let this happen. Please find or do whatever you have to do in order to publish what needs t…

It is a risk, I agree. I can assure you that there is work done in the lab, and that we plan to publish it, one way or another. I personally think that bioRxiv can be perfect to do a fast publication.

Re: Biohackers take aim at big pharma’s stranglehold on insulin

#329
post #78

Every time this stuff comes up it feels like we focus on the politics and not the people with diabetes. If you or your kid or your friends have Type 1 and are struggling to make your insulin out of pockets please, please, please call the Eli Lily hotline and get the copay card. They've dropped the monthly cost for Humalog to $35. Don't ration. Work the system. https://www.humalog.com/savings-support

Every drug company gives away their drugs for free to people who can't afford it in the US. It's sad that not enough people take advantage of patient assistance programs.

> Every drug company gives away their drugs for free to people who can't afford it in the US

No, they don’t all provide their drugs for free, but most of them offer directly or fund assistance programs that provide either free or reduced cost drugs.

Re: Biohackers take aim at big pharma’s stranglehold on insulin

#330

Ignorant newbie question: Similar to a pulse oximeter that measures oxygen saturation non-invasively, is there some research on finding similarly the level of glucose in the blood, etc?

A lot of people have tried, without much luck.

Verily (part of Google/Alphabet) had a joint project with Novartis to build contact lens that sensed glucose in tears, but it didn't pan out.

An analytical chemist has assembled a compendium of approaches that haven't panned out here: http://www.mendosa.com/noninvasive_glucose.pdf

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