Drug users use a lot of drugs • Hacker News Board

Re: Drug users use a lot of drugs

#51

Post by marton78 » Wed, Jun 09, 2021, 9:28 PM UTC

tomcam wrote: post #49

newbie789 wrote: post #32

Former meth addict here. > The average crystal meth addict uses about 500 mg a day. And they snort it, which probably produces about double the peak plasma level as taking it orally. So they're getting the equivalent of 1000 mg oral amphetamine daily... 500mg sounds about right, but from my experience the most common route of administration (in the western United States at least) is smoking, not snorting. Because so…

Might be a regional thing? I was raised in Southern California, where is smoking is also the preferred method. I believe OP is from New York City. For all we know perhaps inhaling what his upper middle class cohort does.

OP is from California.

Re: Drug users use a lot of drugs

#52

Post by thebean11 » Wed, Jun 09, 2021, 9:28 PM UTC

throwaway0a5e wrote: post #19

wincy wrote: post #14

Earlier quoted context omitted.

My neighbors teeth are falling out. Salesman, honestly pretty successful guy, making 6 figures. Apparently he takes 120mg if Adderall to wake up in the morning. At that dose, he’s basically just getting Walter White quality meth for his morning pick me up.

His teeth are far more likely to be falling out because of bad oral hygiene for a decade earlier in life than they are because of a low dose of Adderal or anything. If 120mg of Adderal made your teeth fall out then tons more people would have their teeth falling out.

lol at 120 being a low dose. You start on 10-20.

Re: Drug users use a lot of drugs

#53

Post by vmception » Wed, Jun 09, 2021, 9:30 PM UTC

kriskrunch wrote: post #44

vmception wrote: post #27

Earlier quoted context omitted.

My problem with that, and this article, is that it doesn't say what dosage does that? It just skips right on to meth, and dosages, and never mentions Ketamine again. We get that 280mg a month mostly doesn't, and 90,000mg a month can. But are these "party people" the same as the people doing that higher amount prorated to daily? More specifically, are the "party people" I've been around secretly having bladder problem…

I've known many users over the years, many OD while others decay over a few years. One customer in particular used ketamine heavily. Due to a string of poor decisions, he was on federal probation and subjected to random drug tests. He determined two drugs were not detectible by the tests at that time: ketamine and GHB. And he frequently consumed them. I remember him stumbling around my store, sipping caps of G every…

So we can improve the data by regulating the supply chain, serving sizes, and points of sale

Doesnt seem to support enforcing varying levels of prohibition

Re: Drug users use a lot of drugs

#54

Post by heisenbit » Wed, Jun 09, 2021, 9:33 PM UTC

Drug processing in the body can sometimes be surprising. I learned recently about first pass effect which means the drug heads first to the liver and only what passes through is available to the body. So if one ups the dose and the liver processing is saturated a double dose can deliver much more punch than two single ones. The body has many non-linear features and extrapolating several orders of magnitude is often not possible.

Re: Drug users use a lot of drugs

#55

Post by sharken » Wed, Jun 09, 2021, 9:34 PM UTC

newbie789 wrote: post #32

Former meth addict here. > The average crystal meth addict uses about 500 mg a day. And they snort it, which probably produces about double the peak plasma level as taking it orally. So they're getting the equivalent of 1000 mg oral amphetamine daily... 500mg sounds about right, but from my experience the most common route of administration (in the western United States at least) is smoking, not snorting. Because so…

Must admit the specifics of doing drugs is not that interesting to me, it's more interesting to ask the question:

How does someone stop doing drugs?

Re: Drug users use a lot of drugs

#56

Post by jjulius » Wed, Jun 09, 2021, 9:34 PM UTC

chasebank wrote: post #46

droopyEyelids wrote: post #28

Earlier quoted context omitted.

Let's say you use a 0.5 g dab which has a THC content of 70% (most dabs are either 1-gram or 0.5 g). The wax has 0.35 g (350 mg of THC), but you could lose up to one-third of it when vaporizing. If this happens, you’ll end up with roughly 235 mg of THC per hit (if you can finish the whole dab in one hit). Someone without a THC tolerance will be completely satisfied with a 5mg dose, total. Thats 47 doses out of the 23…

I bought and smoked a 'CBD' joint the other day. 0.47% THC, 15% CBD. I think the lady told me a typical joint is 15-25% THC. I was uncomfortably high.

Had you ever smoked marijuana prior to that?

Re: Drug users use a lot of drugs

#57

Post by Alex3917 » Wed, Jun 09, 2021, 9:36 PM UTC

Somehow he managed to ignore the data showing that a non-trivial percentage of people with KLUTS get it after only doing doses comparable to the psychiatric dose, and sometimes after only doing it once or a handful of times.

https://erowid.org/chemicals/ketamine/ketamine_article2.shtm...

Re: Drug users use a lot of drugs

#58

Post by agentdrtran » Wed, Jun 09, 2021, 9:37 PM UTC

sharken wrote: post #55

newbie789 wrote: post #32

Former meth addict here. > The average crystal meth addict uses about 500 mg a day. And they snort it, which probably produces about double the peak plasma level as taking it orally. So they're getting the equivalent of 1000 mg oral amphetamine daily... 500mg sounds about right, but from my experience the most common route of administration (in the western United States at least) is smoking, not snorting. Because so…

Must admit the specifics of doing drugs is not that interesting to me, it's more interesting to ask the question: How does someone stop doing drugs?

You may get the best answer to that question from people who have stopped rather than never started.

Re: Drug users use a lot of drugs

#59

Post by newbie789 » Wed, Jun 09, 2021, 9:43 PM UTC

sharken wrote: post #55

newbie789 wrote: post #32

Former meth addict here. > The average crystal meth addict uses about 500 mg a day. And they snort it, which probably produces about double the peak plasma level as taking it orally. So they're getting the equivalent of 1000 mg oral amphetamine daily... 500mg sounds about right, but from my experience the most common route of administration (in the western United States at least) is smoking, not snorting. Because so…

Must admit the specifics of doing drugs is not that interesting to me, it's more interesting to ask the question: How does someone stop doing drugs?

I was incredibly lucky. I got to a point where I felt like I wanted to stop (which happens often to a lot of addicts), which coincided with an opportunity to move far away from my hometown, and then also coincidentally found myself surrounded by a fantastic support system. It’s the addict equivalent of flipping a quarter 50 times and having them all come up head.

As for a general answer to your question, there isn’t one that I’m aware of. Everyone I know that’s gotten clean has wildly different stories.

Re: Drug users use a lot of drugs

#60

Post by beebeepka » Wed, Jun 09, 2021, 9:44 PM UTC

newbie789 wrote: post #32

Former meth addict here. > The average crystal meth addict uses about 500 mg a day. And they snort it, which probably produces about double the peak plasma level as taking it orally. So they're getting the equivalent of 1000 mg oral amphetamine daily... 500mg sounds about right, but from my experience the most common route of administration (in the western United States at least) is smoking, not snorting. Because so…

Do regular users also get super horny but unable to perform due... shrinkage?