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Trials begin on lozenge that rebuilds tooth enamel

dental.washington.edu

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Re: Trials begin on lozenge that rebuilds tooth enamel

#311

Post by jb775 »

nickpp wrote: post #274
jb775 wrote: post #165

> The idea for the lozenge design originated with Deniz Yucesoy, a graduate student in the UW’s Genetically Engineered Materials Science and Engineering Center who received a $100,000 Amazon Catalyst grant This grad-student/researcher just handed over a multi-million dollar business to Amazon in exchange for $100k towards the research. Why on Earth would anyone sign over 100% ownership of their idea, just to be able…

> multi-million dollar business That is not a business, just an idea. The value of ideas (unproven, unimplemented) is ZERO. The fact that someone was willing to pay $100k for it is absolutely amazing and a huge service to the society.

This is absolutely wrong. Especially when the formulation of the idea depends on extremely advanced knowledge of the topic.

Re: Trials begin on lozenge that rebuilds tooth enamel

#312

Post by nextos »

nikodunk wrote: post #199
elliekelly wrote: post #80

Earlier quoted context omitted.

Have you looked into botox shots at all? When I tell you my life changed completely from a 15 minute botox appointment with an oral surgeon I am not exaggerating in the least. I’d had no idea what it felt like to live without bruxism - not only were my teeth better but my neck stopped aching, my back muscles stopped spasming, and I stopped getting migraines entirely. I had gotten debilitating migraines once every mon…

Thank you so much for posting this! I’ve ground my teeth badly my whole life, it’s starting to get to the bad parts of my teeth and gums receding etc etc despite retainers, and I’ll definitely look into this! Yours, Guy at the end of his enamel

You may also want to check your neck posture. I've found that, in my case, using laptops invariably leads to bruxism due to poor ergonomics.

Quitting laptops and using a proper desktop, or a laptop stand plus an external keyboard, was like toggling off the bruxism switch. It went off in a week. Plus, I stopped suffering from horrible migraines.

In order to repair your enamel a bit and keep what you have you may want to try toothpastes and creams that contain enamel-like ceramics. I've had spectacular results with a combination of calcium salts, fluoride and hydroxyapatite and ceramics (Novamin). There are better things to add up into the mix right now, such as self-assembling peptide scaffolds.

Re: Trials begin on lozenge that rebuilds tooth enamel

#314

Post by elorant »

StavrosK wrote: post #254
elorant wrote: post #115

Earlier quoted context omitted.

I live in Greece and use the toothpaste regularly. It really works. Prices here are about 4.5 euro each.

We have it? Is it called "repair and protect" here too? I'm gonna get it.

Yeap. Sensodyne Repair & Protect. It's a fairly new product, I accidentally found it at a pharmacy after reading a comment in here. Saw it at a local super market too the other day (sklavenitis).

Re: Trials begin on lozenge that rebuilds tooth enamel

#315

Post by nemo44x »

xyzzy123 wrote: post #102
nemo44x wrote: post #51

Earlier quoted context omitted.

I think about this fairly often. When getting a root canal (it doesn’t hurt!) it’s sort of odd to see in this day and age the tools they use.

I have a friend who needed a major extraction at the panicky start of COVID, in Australia. The dentists weren't allowed to use drills. I'm not sure why but something to do with aerosolizing. It turns out the things dentists use when they're not allowed to use drills are chisels .

There are electronic files today for root canals but I had an endodontist once that still used a series of hand files. So weird to think about.

Re: Trials begin on lozenge that rebuilds tooth enamel

#316

Post by nemo44x »

markdown wrote: post #86
nemo44x wrote: post #55

Earlier quoted context omitted.

Are there any Ph tablets that are effective at neutralizing the acid that isn’t toothpaste? I’ve only recently learned you aren’t supposed to rinse your mouth after brushing!

> I’ve only recently learned you aren’t supposed to rinse your mouth after brushing! Wait, what? Where did you learn that?

Yeah it’s crazy, right? I couldn’t imagine walking around with toothpaste residue but it might also explain the dental work I’ve required.

Google it and you’ll see! I asked my wife about and she concurred that she doesn’t rinse but does get her toothbrush wet while brushing.

Re: Trials begin on lozenge that rebuilds tooth enamel

#317

Post by klipt »

Godel_unicode wrote: post #202
eyelidlessness wrote: post #132

Earlier quoted context omitted.

I was going to mention this too, as well as some of the other warnings. I’ll also add that while it’s extraordinarily effective, 1. It can be counterproductive if you’re experiencing acid reflux, particularly if you’re laying down. The acid neutralization produces a lot of gas (you’ll burp a lot), which can flush acid up your esophagus before it can be neutralized. It’s awful and packaging that discusses its antacid…

> The more you regulate your internal acidity, the more your body will try to find balance... You seem to be full of bad unsubstantiated health advice, for some reason. This is, of course, not true.

There is absolutely a rebound effect where suppressing acid production in the stomach over time causes more acid to be produced:

https://www.npr.org/templates/story/story.php?storyId=112564...

> Stomach cells that make acid multiply over several weeks of exposure to a PPI in an effort to overcome the drug's effect. When the PPI is stopped, they pour out more acid than ever.

Re: Trials begin on lozenge that rebuilds tooth enamel

#318

Post by catillac »

rsync wrote: post #300
benjaminwootton wrote: post #44

There really needs to be something like this. When we look back on dentistry in 50-100 years we will be amazed how barbaric it was! Ouch!

"When we look back on dentistry in 50-100 years we will be amazed how barbaric it was!" Nothing will eclipse the barbarism and "effectiveness" of spinal disc treatments such as spinal fusions.

I’m unfamiliar with this topic, what do you mean? I thought spinal fusion was just a medical procedure to connect a couple vertebrae for some reason, but I thought the downside was a little less flexibility. I wasn’t tracking it being especially barbaric.

Re: Trials begin on lozenge that rebuilds tooth enamel

#319

Post by INTPenis »

Hamuko wrote: post #31

> In addition, the researchers are investigating a gel or solution with the engineered peptide to treat hypersensitive teeth. This problem results from weakness in the enamel that makes the underlying dentin and nerves more vulnerable to heat or cold. Most common products currently on the market can put a layer of organic material on the tooth and numb nerve endings with potassium nitrate, but the relief is only temp…

>I've never had a cavity despite my poor dental hygiene habits and lack of dental practice visits

How old are you?

I was the same until 34 years of age, that's when I bit down on a peanutbutter brittle piece from haagen daazs ice cream and broke my first tooth. After that the visits just piled on.

Now I have one root totally dug out and filled in, (root canal?) and one small hole filled in. I floss daily and brush daily now. I take it seriously. Don't be like me, take it seriously now!

Re: Trials begin on lozenge that rebuilds tooth enamel

#320

Post by Groxx »

fighterpilot wrote: post #248
ce4 wrote: post #235

Earlier quoted context omitted.

Back problems, bruxism, migraines - have you had yourself tested for some bacterial infection like e.g. lyme or bartonella? Just to have that excluded before treating symptoms. I've had all of this for years (more like decades) plus different additional symptoms and got diagnosed last year. The ongoing treatment is not for the faint of heart but symptoms are on the retreat since. PS: I've grown up in rural Germany an…

What other bacterial infections could cause these symptoms aside from lyme and bartonella? Would such an infection be able to explain chronic symptoms over a 1-2 year period?

>Would such an infection be able to explain chronic symptoms over a 1-2 year period?

These symptoms specifically: some at least, I believe. Lyme disease is fairly well known for having severe lasting effects though, years of issues even after treatment is not uncommon at all.

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