Lasting immunity found after recovery from Covid-19 • Hacker News Board

Re: Lasting immunity found after recovery from Covid-19

#141

Post by js2 » Wed, May 12, 2021, 5:29 AM UTC

Also interesting:

“Is One Vaccine Dose Enough After COVID-19 Infection?”

> A small, NIH-supported study, published as a pre-print on medRxiv, offers some early data on this important question [1]. The findings show that immune response to the first vaccine dose in a person who’s already had COVID-19 is equal to, or in some cases better, than the response to the second dose in a person who hasn’t had COVID-19. While much more research is needed—and I am definitely not suggesting a change in the current recommendations right now—the results raise the possibility that one dose might be enough for someone who’s been infected with SARS-CoV-2 and already generated antibodies against the virus.

https://directorsblog.nih.gov/2021/02/23/is-one-dose-of-covi...

Re: Lasting immunity found after recovery from Covid-19

#142

Post by peter_retief » Wed, May 12, 2021, 5:30 AM UTC

I had the virus and completely recovered in line with other viral infections I have had in the past. So this news is unsurprising for me.

Re: Lasting immunity found after recovery from Covid-19

#143

Post by mulvya » Wed, May 12, 2021, 5:30 AM UTC

ianai wrote: post #5

barbazoo wrote: post #2

> The immune systems of more than 95% of people who recovered from COVID-19 had durable memories of the virus up to eight months after infection. > The results provide hope that people receiving SARS-CoV-2 vaccines will develop similar lasting immune memories after vaccination.

The consensus I’m hearing from epidemiologists is the mRNA vaccines should offer better immunity than infection. So it would seem the 8 month for immunity after infection should be a lower bound for the vaccine effectiveness.

Real world experience doesn't show that.

Protection of previous SARS-CoV-2 infection is similar to that of BNT162b2 vaccine protection: A three-month nationwide experience from Israel https://www.medrxiv.org/content/10.1101/2021.04.20.21255670v...

Re: Lasting immunity found after recovery from Covid-19

#144

Post by T-hawk » Wed, May 12, 2021, 5:31 AM UTC

wfhbata wrote: post #131

chrisco255 wrote: post #128

Earlier quoted context omitted.

Liberty. It's a terrible a precedent to restrict freedom of movement on a forced personal health decision. It's basically subverting your body to the state.

It’s a terrible precedent to let people prolong a pandemic and endanger innocent people’s lives in the name of their personal liberties. If you don’t want to take measures to protect others, you can sit home for a while. It won’t kill you, and it won’t kill the people around you.

No, once everyone who wants it is vaccinated, their health is their problem not mine. If anyone is still scared of unvaccinated people, they can keep themselves at home forever, they don't get to force medical choices and restrictions on others.

Re: Lasting immunity found after recovery from Covid-19

#145

Post by halfjoking » Wed, May 12, 2021, 5:32 AM UTC

zacharyvoase wrote: post #137

halfjoking wrote: post #97

Earlier quoted context omitted.

And 15% get worse. Since I’m better, running 5 miles with 0 symptoms afterwards, why risk relapse?

So you don't have long covid then?

I haven't had neuro/heart/gastro issues for months. My veins still bulge sometimes. Once every few days I get the hot-skin. Other than those symptoms I don't.

Re: Lasting immunity found after recovery from Covid-19

#146

Post by unishark » Wed, May 12, 2021, 5:32 AM UTC

wfhbata wrote: post #131

chrisco255 wrote: post #128

Earlier quoted context omitted.

Liberty. It's a terrible a precedent to restrict freedom of movement on a forced personal health decision. It's basically subverting your body to the state.

It’s a terrible precedent to let people prolong a pandemic and endanger innocent people’s lives in the name of their personal liberties. If you don’t want to take measures to protect others, you can sit home for a while. It won’t kill you, and it won’t kill the people around you.

I think they should require vaccination for travel (and schools and many other things) but I also think it is a problematic precedent.

How is limiting state power during a particular emergency situation a terrible precedent? The state can always grab more power at a later emergency, as history has shown. The difficult task is getting them to give up power once it is no longer needed for the emergency.

Re: Lasting immunity found after recovery from Covid-19

#147

Post by selcuka » Wed, May 12, 2021, 5:33 AM UTC

koolba wrote: post #62

HWR_14 wrote: post #57

Earlier quoted context omitted.

From my understanding, there are two main reasons. 1) The two spaced exposures. Repeated spaced exposures build a significantly stronger response. 2) Isolation of the spike protein. Just like ML might pick up on a correlated part of the image while learning to recognize things (many examples, no good links), your immune system may learn to react to different parts of the virus. The spike protein is the most unchangin…

> The spike protein is the most unchanging part, and all the vaccine will teach your body to attack. Does that mean that a natural immunity may offer protection against other coronaviruses that have a different spike protein structure? The logic being that the less targeted defenses built through a natural immunity would latch onto some other commonality?

As far as I understand it is less likely for the spike protein to have a radical mutation and keep the ability to attach to cells at the same time. That's why the variants we are seeing have the same spike protein as other mutations of the virus tend to quickly disappear.

If a new variant with a different spike emerges, I guess we'll call it SARS-CoV-3 and produce a new mRNA vaccine for it.

Re: Lasting immunity found after recovery from Covid-19

#148

Post by jader201 » Wed, May 12, 2021, 5:35 AM UTC

breck wrote: post #76

Israel has been tracking a cohort of 150,000 and the reinfection rate looks to be on the order of 1 in 1,000. > https://www.medrxiv.org/content/10.1101/2021.03.06.21253051v...

Is that within the margin of error for false positive tests? IOW, maybe the 1 in 1000 didn’t actually have COVID the first/second time?

Re: Lasting immunity found after recovery from Covid-19

#149

Post by stormbrew » Wed, May 12, 2021, 5:36 AM UTC

chrisco255 wrote: post #128

azinman2 wrote: post #125

Earlier quoted context omitted.

Why not require vaccination?

Liberty. It's a terrible a precedent to restrict freedom of movement on a forced personal health decision. It's basically subverting your body to the state.

The precedent has been set for a long time now already, and it likely saves a lot of lives. https://www.who.int/ith/2016-ith-county-list.pdf

This isn't rocket science. I don't know where people get this idea that international travel was some kind of libertarian utopia before covid. There are a lot of things that restrict your ability to travel, and vaccinations are one of the least problematic.

Re: Lasting immunity found after recovery from Covid-19

#150

Post by peteretep » Wed, May 12, 2021, 5:37 AM UTC

chrisco255 wrote: post #128

azinman2 wrote: post #125

Earlier quoted context omitted.

Why not require vaccination?

Liberty. It's a terrible a precedent to restrict freedom of movement on a forced personal health decision. It's basically subverting your body to the state.

It’s not personal health, tho, it’s public health.