71–80 of 342 posts
Out of curiosity, why do vaccines like polio protect us for life, but ones for coronavirus only for a couple of years?
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Natural immunity and vaccine immunity are expected to last around the same amount time. This is for the simple reason that the mechanism that generates the immunity is similar. (Natural immunity being a bit more diverse, while vaccine focuses on a single protein.)
Possibly not. I can't really follow most of this, but from the abstract it sounds like the (Pfizer) vaccines don't necessarily trigger a B-cell/T-cell reaction unless you've previously been infected (in which case the vaccines strengthen what was already there due to natural immunity), and that's where long-lasting immunity comes from, since antibodies will eventually degrade over time (we're just not sure how long i…
For people that haven't been previously infected, the second dose is the similar booster.
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> The consensus I’m hearing from epidemiologists is the mRNA vaccines should offer better immunity than infection Serious question: How can we possibly know this? I'm all for vaccinations (I'm going in for my second shot this weekend), but I just worry about commentary backed by intuition that doesn't carry sufficient disclaiming.
I had this exact question and asked around before finding out a friend's brother specializes in immunology. Apparently two separate exposures triggers a much longer lasting immune response, and because of the nature of the vaccine it's much more targeted to one specific aspect of the virus, and consequently more potent in a way. Moderna also made a statement that they expected their vaccine to last for 2 years based…
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>People that contracted SARS-CoV-1 still have a strong immune response almost 20 years later. Could you provide a source for this please?
There are several such studies, all trivially discoverable. Here is one published in Nature last year, where they specifically also studied cross reactivity of SARS-2003 immune response with SARS-2019: https://www.nature.com/articles/s41586-020-2550-z Asking for a citation for something so trivially discoverable is a weird flex.
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There are several such studies, all trivially discoverable. Here is one published in Nature last year, where they specifically also studied cross reactivity of SARS-2003 immune response with SARS-2019: https://www.nature.com/articles/s41586-020-2550-z Asking for a citation for something so trivially discoverable is a weird flex.
Ridiculing someone for asking for a source for something you think is "trivial" is also a weird flex.
> https://www.medrxiv.org/content/10.1101/2021.03.06.21253051v...
SINGAPORE - The Republic has seen 26 cases of Covid-19 reinfection as Monday (May 10), Health Minister Gan Kim Yong said in a ministerial statement in Parliament on Tuesday. Such reinfections are known to be possible in both overseas and local cases, he noted, but it is still unclear why they occur. The minister said investigations are ongoing to determine if reinfections are due to a general waning of immunity level…
This one's close to my heart since I stay there. At the end of the article: > there have been 56 cases involving people who were infected despite being fully vaccinated, of which 30 were local cases and 26 were imported ones.
What that means is that fully vaccinated individuals can get infected and infect unvaccinated individuals. As such, your population won't be protected unless most people are vaccinated (80-90%+).
I’m very surprised that “proof of immunity” isn’t an acceptable alternative to a vaccine for things like travel or work. It seems it’s either vaccine or bust. Anyone know why this is the case?
I'm hoping it will be since I have longcovid and don't want the vaccine. Anyone who is willing to pay for the new T-Cell test [1] and is positive should be given the same rights as any vaccine passport provides. [1] https://www.bloomberg.com/news/articles/2021-02-23/t-cell-sc...
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From my understanding, there are two main reasons. 1) The two spaced exposures. Repeated spaced exposures build a significantly stronger response. 2) Isolation of the spike protein. Just like ML might pick up on a correlated part of the image while learning to recognize things (many examples, no good links), your immune system may learn to react to different parts of the virus. The spike protein is the most unchangin…
> The spike protein is the most unchanging part, and all the vaccine will teach your body to attack. Does that mean that a natural immunity may offer protection against other coronaviruses that have a different spike protein structure? The logic being that the less targeted defenses built through a natural immunity would latch onto some other commonality?
I’m very surprised that “proof of immunity” isn’t an acceptable alternative to a vaccine for things like travel or work. It seems it’s either vaccine or bust. Anyone know why this is the case?