Lasting immunity found after recovery from Covid-19 • Hacker News Board

Re: Lasting immunity found after recovery from Covid-19

#11

Post by InvertedRhodium » Wed, May 12, 2021, 2:35 AM UTC

ianai wrote: post #5

barbazoo wrote: post #2

> The immune systems of more than 95% of people who recovered from COVID-19 had durable memories of the virus up to eight months after infection. > The results provide hope that people receiving SARS-CoV-2 vaccines will develop similar lasting immune memories after vaccination.

The consensus I’m hearing from epidemiologists is the mRNA vaccines should offer better immunity than infection. So it would seem the 8 month for immunity after infection should be a lower bound for the vaccine effectiveness.

Given the amount of pseudo-science, false claims, wishful thinking, etc - got a source on that?

Re: Lasting immunity found after recovery from Covid-19

#12

Post by paxys » Wed, May 12, 2021, 2:38 AM UTC

This is promising. Anecdotally though, I know people in India who got covid (with symptoms) twice or even thrice over the last 12 months. I imagine antibody generation is different for different people, and/or response to variants of the virus is different.

Re: Lasting immunity found after recovery from Covid-19

#13

Post by ed25519FUUU » Wed, May 12, 2021, 2:38 AM UTC

I’m very surprised that “proof of immunity” isn’t an acceptable alternative to a vaccine for things like travel or work. It seems it’s either vaccine or bust. Anyone know why this is the case?

Re: Lasting immunity found after recovery from Covid-19

#14

Post by macksd » Wed, May 12, 2021, 2:40 AM UTC

dnautics wrote: post #10

ianai wrote: post #5

Earlier quoted context omitted.

The consensus I’m hearing from epidemiologists is the mRNA vaccines should offer better immunity than infection. So it would seem the 8 month for immunity after infection should be a lower bound for the vaccine effectiveness.

> The consensus I’m hearing from epidemiologists is the mRNA vaccines should offer better immunity than infection Serious question: How can we possibly know this? I'm all for vaccinations (I'm going in for my second shot this weekend), but I just worry about commentary backed by intuition that doesn't carry sufficient disclaiming.

I had this exact question and asked around before finding out a friend's brother specializes in immunology. Apparently two separate exposures triggers a much longer lasting immune response, and because of the nature of the vaccine it's much more targeted to one specific aspect of the virus, and consequently more potent in a way. Moderna also made a statement that they expected their vaccine to last for 2 years based on their ability to measure the number of antibodies and its decline over time [1].

[1] https://www.reuters.com/article/us-health-coronavirus-modern...

Re: Lasting immunity found after recovery from Covid-19

#15

Post by jandrewrogers » Wed, May 12, 2021, 2:40 AM UTC

This was completely expected, since this is the case with the other coronaviruses. People that contracted SARS-CoV-1 still have a strong immune response almost 20 years later.

Re: Lasting immunity found after recovery from Covid-19

#16

Post by flobosg » Wed, May 12, 2021, 2:41 AM UTC

Here’s the paper: https://science.sciencemag.org/content/371/6529/eabf4063.lon...

Re: Lasting immunity found after recovery from Covid-19

#17

Post by whiddershins » Wed, May 12, 2021, 2:41 AM UTC

So just like basically every similar disease?

As in, our immune systems work more or less like we’ve thought for decades?

Re: Lasting immunity found after recovery from Covid-19

#18

Post by [deleted] » Wed, May 12, 2021, 2:41 AM UTC

ianai wrote: post #5

barbazoo wrote: post #2

> The immune systems of more than 95% of people who recovered from COVID-19 had durable memories of the virus up to eight months after infection. > The results provide hope that people receiving SARS-CoV-2 vaccines will develop similar lasting immune memories after vaccination.

The consensus I’m hearing from epidemiologists is the mRNA vaccines should offer better immunity than infection. So it would seem the 8 month for immunity after infection should be a lower bound for the vaccine effectiveness.

[deleted]

Re: Lasting immunity found after recovery from Covid-19

#19

Post by daenz » Wed, May 12, 2021, 2:43 AM UTC

jandrewrogers wrote: post #15

This was completely expected, since this is the case with the other coronaviruses. People that contracted SARS-CoV-1 still have a strong immune response almost 20 years later.

>People that contracted SARS-CoV-1 still have a strong immune response almost 20 years later.

Could you provide a source for this please?

Re: Lasting immunity found after recovery from Covid-19

#20

Post by TrispusAttucks » Wed, May 12, 2021, 2:45 AM UTC

macksd wrote: post #14

dnautics wrote: post #10

Earlier quoted context omitted.

> The consensus I’m hearing from epidemiologists is the mRNA vaccines should offer better immunity than infection Serious question: How can we possibly know this? I'm all for vaccinations (I'm going in for my second shot this weekend), but I just worry about commentary backed by intuition that doesn't carry sufficient disclaiming.

I had this exact question and asked around before finding out a friend's brother specializes in immunology. Apparently two separate exposures triggers a much longer lasting immune response, and because of the nature of the vaccine it's much more targeted to one specific aspect of the virus, and consequently more potent in a way. Moderna also made a statement that they expected their vaccine to last for 2 years based…

Yes. So long as no mutation takes place on the protein spike.