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Lasting immunity found after recovery from Covid-19

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21–30 of 342 posts

Re: Lasting immunity found after recovery from Covid-19

#21

I’m very surprised that “proof of immunity” isn’t an acceptable alternative to a vaccine for things like travel or work. It seems it’s either vaccine or bust. Anyone know why this is the case?

It is possible that consensus will shift towards that as soon as people start forging vaccine passports en masse and for more things

Proof of immunity can have the server side component for verification, which was neglected for the vaccination effort

Re: Lasting immunity found after recovery from Covid-19

#22
post #14

Earlier quoted context omitted.

> The consensus I’m hearing from epidemiologists is the mRNA vaccines should offer better immunity than infection Serious question: How can we possibly know this? I'm all for vaccinations (I'm going in for my second shot this weekend), but I just worry about commentary backed by intuition that doesn't carry sufficient disclaiming.

I had this exact question and asked around before finding out a friend's brother specializes in immunology. Apparently two separate exposures triggers a much longer lasting immune response, and because of the nature of the vaccine it's much more targeted to one specific aspect of the virus, and consequently more potent in a way. Moderna also made a statement that they expected their vaccine to last for 2 years based…

My original intuition was it would be the opposite.

This actually makes a lot of sense.

Thanks for sharing and correcting my line of thinking on it.

Re: Lasting immunity found after recovery from Covid-19

#23
post #14

Earlier quoted context omitted.

> The consensus I’m hearing from epidemiologists is the mRNA vaccines should offer better immunity than infection Serious question: How can we possibly know this? I'm all for vaccinations (I'm going in for my second shot this weekend), but I just worry about commentary backed by intuition that doesn't carry sufficient disclaiming.

I had this exact question and asked around before finding out a friend's brother specializes in immunology. Apparently two separate exposures triggers a much longer lasting immune response, and because of the nature of the vaccine it's much more targeted to one specific aspect of the virus, and consequently more potent in a way. Moderna also made a statement that they expected their vaccine to last for 2 years based…

They also measured significantly higher density of antibodies at the six week mark in people who had their second vaccine dose vs people who recovered from an infection.

Re: Lasting immunity found after recovery from Covid-19

#24
post #14

Earlier quoted context omitted.

I had this exact question and asked around before finding out a friend's brother specializes in immunology. Apparently two separate exposures triggers a much longer lasting immune response, and because of the nature of the vaccine it's much more targeted to one specific aspect of the virus, and consequently more potent in a way. Moderna also made a statement that they expected their vaccine to last for 2 years based…

Yes. So long as no mutation takes place on the protein spike.

Mind you, it is a protein. So you're banking on the virus encoding a different/new protein that still binds to ACE2.

Re: Lasting immunity found after recovery from Covid-19

#25

I’m very surprised that “proof of immunity” isn’t an acceptable alternative to a vaccine for things like travel or work. It seems it’s either vaccine or bust. Anyone know why this is the case?

Testing for immunity could easily cost more than the vaccine. Also most people haven't caught it yet, so you'd need to give them the vaccine anyways.

Re: Lasting immunity found after recovery from Covid-19

#26
post #5

Earlier quoted context omitted.

The consensus I’m hearing from epidemiologists is the mRNA vaccines should offer better immunity than infection. So it would seem the 8 month for immunity after infection should be a lower bound for the vaccine effectiveness.

As much as I'd like that to be true, I think it's impossible to separate that statement from the political pressure to motivate vaccination. ie, if the opposite was true — vaccination did not provide the same strength of immunity as infection — no epidemiologist would ever state this publicly. So I'll be happy if it's true, but this statement doesn't move my belief-meter one way or another.

You know these studies publish their data, right? You can look at it yourself.

Re: Lasting immunity found after recovery from Covid-19

#27
post #5

Earlier quoted context omitted.

The consensus I’m hearing from epidemiologists is the mRNA vaccines should offer better immunity than infection. So it would seem the 8 month for immunity after infection should be a lower bound for the vaccine effectiveness.

As much as I'd like that to be true, I think it's impossible to separate that statement from the political pressure to motivate vaccination. ie, if the opposite was true — vaccination did not provide the same strength of immunity as infection — no epidemiologist would ever state this publicly. So I'll be happy if it's true, but this statement doesn't move my belief-meter one way or another.

The public health profession has lost so much credibility over the last year. No one should feel the need to reverse engineer latent preemptive anticipatory inverted Stockholm syndrome like this, but here we are.

Re: Lasting immunity found after recovery from Covid-19

#28
post #19

This was completely expected, since this is the case with the other coronaviruses. People that contracted SARS-CoV-1 still have a strong immune response almost 20 years later.

>People that contracted SARS-CoV-1 still have a strong immune response almost 20 years later. Could you provide a source for this please?

There are several such studies, all trivially discoverable. Here is one published in Nature last year, where they specifically also studied cross reactivity of SARS-2003 immune response with SARS-2019:

https://www.nature.com/articles/s41586-020-2550-z

Asking for a citation for something so trivially discoverable is a weird flex.

Re: Lasting immunity found after recovery from Covid-19

#29
post #12

This is promising. Anecdotally though, I know people in India who got covid (with symptoms) twice or even thrice over the last 12 months. I imagine antibody generation is different for different people, and/or response to variants of the virus is different.

Not that I doubt you, but it is pretty common here in the USA to _assume_ every cold/allergy etc. is COVID-19, even without a positive PCR or anti-gen test. Did the folks you know get positively tested, or did sx just match?

Re: Lasting immunity found after recovery from Covid-19

#30
post #14

Earlier quoted context omitted.

I had this exact question and asked around before finding out a friend's brother specializes in immunology. Apparently two separate exposures triggers a much longer lasting immune response, and because of the nature of the vaccine it's much more targeted to one specific aspect of the virus, and consequently more potent in a way. Moderna also made a statement that they expected their vaccine to last for 2 years based…

Yes. So long as no mutation takes place on the protein spike.

And this part I'm less confident in, but my understanding is the protein spike is unlikely to mutate because it's exactly what allows the virus to bind where it does. If that mutated and that mutation was still somehow successful, I believe it likely wouldn't be as bad a virus.
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