The thing that kills me about the ticketing systems is that they are often put into place in a way that is locally efficient but does not make sense globally.
For example, an application owner might have to submit a ticket to request an upgrade once a year (or when a new OS is supported). What often happens is that the application owner now has to know about, find, and correctly understand a form that they see once (or less) per year. That work has been offloaded from a single team (measurable impact to efficiency) to immeasurable shadow work for others in the organization. A form that would take 1 minute of effort from the team that runs the upgrade to fill out and track, because they are in it all day, ends up taking a half hour, cut across multiple starts and stops due to other similar interruptions.
This becomes pervasive (book your own travel with this system, book your own PTO here, track your time here, fill out tickets for this system, use the help desk ticketing system to request an application installation) and ends up eating a huge chunk of employee time doing unfamiliar overhead tasks on systems optimized for the team doing the work and not the customer. I think we are getting to the point where all of the systems that were designed to take away the need for administrative assistants may once again require an assistant to navigate efficiently.