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Coffee drinkers display a distinct pattern of brain functional connectivity

nature.com

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Re: Coffee drinkers display a distinct pattern of brain functional connectivity

#21

Post by graderjs »

xyzzyz wrote: post #12
barnabees wrote: post #3

"Fifty-six subjects were recruited (32 CD and 24 NCD). One participant from the CD group was excluded due to imaging artifacts, rendering a final sample of 31 CD and 24 NCD." Feels too small of a sample size to make any strong conclusions

Not necessarily. Suppose, for simplicity, that we have equal number N of coffee drinkers and non coffee drinkers, for total of 2N. Suppose you try your model on them, and tell which is which based on their MRI 80% of the time. Let’s assume the null hypothesis is that you model doesn’t work, and you just were randomly lucky. If N = 5, that’s 8 successes in 10 Bernoulli trials, that’s already p value of 0.01. With N=25…

Thank you for this. It's annoying to see people dismiss studies based some general idea of "not enough people" without being backed by the numbers. Great to see someone back it up!

Re: Coffee drinkers display a distinct pattern of brain functional connectivity

#22

Post by WalterBright »

When the pandemic started a year ago, I laid in a supply of coffee. The supply chain for that is very long, and I'd miss it terribly!

I expected coffee shortages at the supermarket, but weirdly everyone else was buying yeast and toilet paper. Couldn't buy yeast for like 6 months. The coffee supply was unaffected, for which I am grateful!

Re: Coffee drinkers display a distinct pattern of brain functional connectivity

#24

Post by lysp »

mensetmanusman wrote: post #5

Coffee is the best drink ever, but how do we get it to taste as good as it smells?

Best way to get flavour out of coffee is cold brew (not cold trip).

Leave coarsely ground coffee in water for 12-24 hours at room temperature and then filter the beans out.

Lasts for about 2 weeks in the fridge and you can have it straight, with ice, water or milk.

Some coffee shops use this technique to find out the flavour of coffee prior to using it for hot coffee. As the heat denatures some of the proteins in coffee, doing it cold extracts all the flavours without damage.

Otherwise find a good espresso place (not a chain). I have no idea how many or if they are around in US much.

Re: Coffee drinkers display a distinct pattern of brain functional connectivity

#25

Post by markdown »

yeutterg wrote: post #15
mensetmanusman wrote: post #5

Coffee is the best drink ever, but how do we get it to taste as good as it smells?

What is your experience with coffee? Have you mostly had Stabucks/Dunkin/Folgers and the like or have you ventured out into trying third wave coffees? I recommend getting a drink from a third wave coffee shop if you haven't already. Great coffee comes down to many factors: the beans, roasting, grind, brew method, and temperature. A great resource for learning more about great coffee is James Hoffmann's YouTube channe…

> Great coffee comes down to many factors: the beans, roasting, grind, brew method, and temperature.

Sounds like what wine salesmen say.

Re: Coffee drinkers display a distinct pattern of brain functional connectivity

#26

Post by objektif »

dnautics wrote: post #18
koolba wrote: post #14

Earlier quoted context omitted.

By doing absolutely nothing. Drinking and enjoying black coffee is like whiskey, it takes a few times to get past the “ why the hell would anyone?! ” hump, but once you do, you never look back.

There's terrible coffee out there. In my opinion (you may differ) Peet's black coffee tastes like burning and I regret it every time, usually in aeroport terminals (I always drink black so I often forget to order Peet's cut with adulterants like dairy). Tastes are different; I hate really expensive trad whiskeys (Islay, Oban) because there's something in there that tastes to me like the smell of plastic shrinkwrap ar…

Where do you live? If you are in NYC I can recommend a few places to try that will change your mind about coffee.

Re: Coffee drinkers display a distinct pattern of brain functional connectivity

#28

Post by denkmoon »

kbenson wrote: post #11
mensetmanusman wrote: post #5

Coffee is the best drink ever, but how do we get it to taste as good as it smells?

Copious amounts of sugar and fat seem to work for most people. That said, yes, I would love to know how to make it more palatable without making it so unhealthy. I'm extremely sensitive to bitter flavors, black coffee is a lost cause for me.

> I'm extremely sensitive to bitter flavors, black coffee is a lost cause for me.

Perhaps coffee just isn't for you? The bitterness is part of what is enjoyable.

Tea is probably more your thing.

Re: Coffee drinkers display a distinct pattern of brain functional connectivity

#29

Post by throwaway823882 »

mensetmanusman wrote: post #5

Coffee is the best drink ever, but how do we get it to taste as good as it smells?

First, buy good beans. https://www.javapresse.com/blogs/buying-coffee/ultimate-guid...

Second, buy a cheap hand grinder and grind 'em right. https://www.javapresse.com/blogs/grinding-coffee/grinder-bes...

Third, buy a cheap plastic V60 funnel and some paper filters, and hand-pour. https://www.youtube.com/watch?v=AI4ynXzkSQo

If you're just learning how to do this, buy a good bag of coffee just to practice a bunch until you taste a difference. (Do this any time you learn to cook. Cook 36 eggs in one go and you will become an expert omelette maker in an hour)

Cold brew is also delicious. Both the "let it sit overnight" variety, and "brewing into a carafe of ice".

Oh, and clean all your stuff each time before you use it. Stale leftover coffee (in your brewer or coffee mug) makes your coffee taste like shit.

Re: Coffee drinkers display a distinct pattern of brain functional connectivity

#30

Post by tjbiddle »

mensetmanusman wrote: post #5

Coffee is the best drink ever, but how do we get it to taste as good as it smells?

Use high quality beans, keep them fresh in a sealed container aways.

Grind for the appropriate brewing technique.

Use an AeroPress or a French Press, use water that has been boiled and just finished dropping past the bubbling point.

Let it steep, and stir.

Drink it black, and get used to it.

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