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Coffee drinkers display a distinct pattern of brain functional connectivity

nature.com

11–20 of 119 posts

Re: Coffee drinkers display a distinct pattern of brain functional connectivity

#11

Coffee is the best drink ever, but how do we get it to taste as good as it smells?

Copious amounts of sugar and fat seem to work for most people.

That said, yes, I would love to know how to make it more palatable without making it so unhealthy. I'm extremely sensitive to bitter flavors, black coffee is a lost cause for me.

Re: Coffee drinkers display a distinct pattern of brain functional connectivity

#12

"Fifty-six subjects were recruited (32 CD and 24 NCD). One participant from the CD group was excluded due to imaging artifacts, rendering a final sample of 31 CD and 24 NCD." Feels too small of a sample size to make any strong conclusions

Not necessarily. Suppose, for simplicity, that we have equal number N of coffee drinkers and non coffee drinkers, for total of 2N. Suppose you try your model on them, and tell which is which based on their MRI 80% of the time. Let’s assume the null hypothesis is that you model doesn’t work, and you just were randomly lucky. If N = 5, that’s 8 successes in 10 Bernoulli trials, that’s already p value of 0.01. With N=25 (close to the study), that’s p-value of 0.002, much better than random chance.

Whether N = 50 is too small sample really depends on the strength of the effect you are trying to detect. For strong effects it’s plenty enough.

Re: Coffee drinkers display a distinct pattern of brain functional connectivity

#13

Coffee is the best drink ever, but how do we get it to taste as good as it smells?

Coffee, done right, is delicious.

A high quality bean, appropriately roasted, relatively fresh, freshly ground immediately before use with a bur grinder, and then your choice of method, plenty of grinds but almost always hot water, and preferably some pressure to extract oils, finally filtered through paper.

My weapon of choice is an aeropress or a manual espresso press. An Americano is arguably superior to a cup of drip. I drink it black.

Coffee is fucking delicious.

Re: Coffee drinkers display a distinct pattern of brain functional connectivity

#14

Coffee is the best drink ever, but how do we get it to taste as good as it smells?

By doing absolutely nothing.

Drinking and enjoying black coffee is like whiskey, it takes a few times to get past the “why the hell would anyone?!” hump, but once you do, you never look back.

Re: Coffee drinkers display a distinct pattern of brain functional connectivity

#15

Coffee is the best drink ever, but how do we get it to taste as good as it smells?

What is your experience with coffee? Have you mostly had Stabucks/Dunkin/Folgers and the like or have you ventured out into trying third wave coffees? I recommend getting a drink from a third wave coffee shop if you haven't already.

Great coffee comes down to many factors: the beans, roasting, grind, brew method, and temperature.

A great resource for learning more about great coffee is James Hoffmann's YouTube channel: https://www.youtube.com/channel/UCMb0O2CdPBNi-QqPk5T3gsQ

Re: Coffee drinkers display a distinct pattern of brain functional connectivity

#16

Coffee is the best drink ever, but how do we get it to taste as good as it smells?

A quality grinder will allow you to dial in the ratio of fines to dissolved solids. An oversimplification is that espresso is mostly fines (let rest and you have sludge), and coffee is mostly dissolved solids.

I prefer a coffee that is done at a low temperature (80-85c) and ground more towards an espresso to pull a little more flavor out.

I use a Commandants C40 with 40 grind settings.

Re: Coffee drinkers display a distinct pattern of brain functional connectivity

#18
post #14

Coffee is the best drink ever, but how do we get it to taste as good as it smells?

By doing absolutely nothing. Drinking and enjoying black coffee is like whiskey, it takes a few times to get past the “ why the hell would anyone?! ” hump, but once you do, you never look back.

There's terrible coffee out there. In my opinion (you may differ) Peet's black coffee tastes like burning and I regret it every time, usually in aeroport terminals (I always drink black so I often forget to order Peet's cut with adulterants like dairy).

Tastes are different; I hate really expensive trad whiskeys (Islay, Oban) because there's something in there that tastes to me like the smell of plastic shrinkwrap around vegetables from the japanese markets -- it's not peat, it's something else. But the cheap stuff I don't mind, and suntories are pretty good too.

Re: Coffee drinkers display a distinct pattern of brain functional connectivity

#20
post #11

Coffee is the best drink ever, but how do we get it to taste as good as it smells?

Copious amounts of sugar and fat seem to work for most people. That said, yes, I would love to know how to make it more palatable without making it so unhealthy. I'm extremely sensitive to bitter flavors, black coffee is a lost cause for me.

A Cappuccino is delicious, lightly sweet and hard to make at home. But you may try it out.
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