Scientists who say the lab-leak hypothesis for SARS-CoV-2 shouldn't be ruled out

But I hate the stupid racism and hate around it. COVID-19 attacked every country. With the exception of, like, New Zealand (but it affected them as well... had to shut down their borders, etc).

These viruses are a threat to all humanity. I just want us to fight them better and help everyone.

I think it's super important that we both simultaneously hold China accountable (rhetorically, in the social sphere at very least) for aggressive expansionary actions (i.e. vs Hong Kong, Taiwan, the Philippines) and human rights abuses (Uighur, etc)...

...while simultaneously trying to help everyone do better, including the Chinese, to face common threats (like novel viruses, climate change, etc). And we must not start up a new Cold War with all its proxy conflicts, death, and unnecessary economic suffering and threat of annihilation.

All seem plausible because...

1) gain of function research is super risky and there have been lab escapes before. We need to do MUCH better about lab leaks. We should spend more on security and have greater transparency. We should also question whether it even makes sense to do that kind of research.

2) Same thing for natural research sample being leaked...

3) wet markets are probably a really bad idea. And we should probably keep a better eye on natural virus variants, HOWEVER... that's somewhat in conflict with the "maybe this research isn't worth it" line of thinking.

So we have some somewhat hard trade-offs, here, but there are aspects where we can just do better. Like, whenever we do do research on viruses, we should probably be a LOT more careful about how and when we do it.

And although it's very unlikely the virus was engineered, we should probably be careful with the technology that would let it be engineered. The technology that makes sequencing novel virus strains and developing novel vaccines using mRNA also makes it easier to engineer a virus. This is a tough one because if we had clamped down super hard on mRNA tech too early, we would've been perhaps unprepared to make a vaccine...

I read your post on Reddit back in the day. It was evasive and frankly condescending because you basically argue against something no-one familiar with the science is claiming: that COV is a chimeric virus that is the product of copy-and-paste genetic manipulation rather than directed evolution or gain-of-function research that has resulted in phylogenetic drift against something that was found in the wild -- most likely RaTG13.

And why should anyone take your writing seriously when you don't even talk about "gain of function" research or the various other techniques that have been used in the past decade to aerosolize viruses like H5N1? If you know about them and are deliberately omitting all mention and analysis you are just being dishonest. If you don't then you clearly aren't an expert.

There are also lots of on-topic scientific claims you could address that would let people evaluate your competence and also provide illumination -- what do statistical models say about how long it would take for RaTG13 to evolve into COV19 in the wild? What about in a lab? How likely or unlikely it is to find virii so far away from known ancestors? What are the chances of finding them once we start looking in the wild -- should we have expected to find a closer ancestor by now? And what about the claims made by the State Department about WIV, its closure in September (related: who in the West should be able to confirm/deny if this is the case)? I'd also personally be interested to hear how long it takes to develop research mice with ACE2 receptors since their existence by mid-2020 surely suggests a targeted research agenda that preceded the outbreak? Could scientists in Beijing really have done that in 2 months or whatever?

If you want to be taken seriously, you need to frame the top two or three most credible lab-escape scenarios that work with what is actually public knowledge. Then address the evidence for and against. Setting up strawmen argument, knocking them down and then virtue-signalling on racism isn't useful or on-topic.

Mutations are entirely random, usually deletrious. Evolutionary pressure is the selection for fitness.