Hacker News Board Hacker News, browsed like a classic message board
Live data from Hacker News

Suppressing a gene by using its antibody can lead to tooth growth: animal study

u-fukui.ac.jp

Post reply on HN
Print view View original

101–110 of 163 posts

Re: Suppressing a gene by using its antibody can lead to tooth growth: animal study

#101

Post by ClumsyPilot »

xenadu02 wrote: post #81
dannyw wrote: post #31

Earlier quoted context omitted.

It's so sad that most dentists optimise for billable revenue, even at the detriment of long term patient health. Fillings for example always degrade and need repairs after X years. Drilling and filling even the smallest cavity puts that teeth on a lifetime progression to bigger and bigger fillings, eventually a root canal, eventually an implant. Cavities, on the other hand can be arrested (stopped), and if small can…

My dentist simply put me on toothpaste with high fluoride (IIRC 8%?). Two caries remineralized over the span of about a year and I didn't need fillings. Unfortunately high fluoride toothpastes require an RX.

Whats an RX?

Re: Suppressing a gene by using its antibody can lead to tooth growth: animal study

#102

Post by preciz »

refurb wrote: post #67
dannyw wrote: post #33

Earlier quoted context omitted.

I don't know. We see pharma companies killing one-time cures to not cannibalise recurring treatments, even if another company makes the recurring treatments.

Yet one of the biggest selling products ever was a cure for hepatitis C. Pharma hiding cures is internet BS.

That is one example that was interpreted by you to be valid for all other cases? Seeing your other comments I think you highly trust the medical system. Never trust blindly my friend.

Re: Suppressing a gene by using its antibody can lead to tooth growth: animal study

#103

Post by ClumsyPilot »

Jeff_Brown wrote: post #2

The article linked says it causes new teeth to grow in rats and ferrets, and that pugs and dogs are next. It doesn't however talk about targeting that growth to a particular place.

as long as they are only growing in your mouth, thats still a solution.

Now, having teeth grow om your body randomly, thats a horror movie

Re: Suppressing a gene by using its antibody can lead to tooth growth: animal study

#104

Post by zeta0134 »

ClumsyPilot wrote: post #101
xenadu02 wrote: post #81

Earlier quoted context omitted.

My dentist simply put me on toothpaste with high fluoride (IIRC 8%?). Two caries remineralized over the span of about a year and I didn't need fillings. Unfortunately high fluoride toothpastes require an RX.

Whats an RX?

For some reason, that's short for "prescription."

English is weird.

Re: Suppressing a gene by using its antibody can lead to tooth growth: animal study

#105

Post by seer »

mdpopescu wrote: post #94
NiceWayToDoIT wrote: post #92

Although amazing, I am following similar news for last 20 years, and promise of tooth regrowth was as a holly grail of dental health, but on the other side it is similar like a nuclear fusion always 20 years away. Process goes like this, "big news -> excitement -> and then nothing -> few years later again nothing -> you go to you dentist for regular check and when you ask he laughs in your face." I read about steam c…

As a general rule, the entire medical profession has the incentives set up the wrong way - the more problems you have, the more they benefit. I have read that there was a time, in the distant past, where you paid a doctor only as long as you were healthy. I can come up with some problems even in that case, but I can't help but think it might still be an improvement over the current situation...

I think I’ve read somewhere about this being an old Chinese tradition. They would pay doctors for the amount pf people he is looking after, and he has the incentive to keep his “flock” healthy as that would mean much less work for him.

Re: Suppressing a gene by using its antibody can lead to tooth growth: animal study

#107

Post by bipson »

mdpopescu wrote: post #94
NiceWayToDoIT wrote: post #92

Although amazing, I am following similar news for last 20 years, and promise of tooth regrowth was as a holly grail of dental health, but on the other side it is similar like a nuclear fusion always 20 years away. Process goes like this, "big news -> excitement -> and then nothing -> few years later again nothing -> you go to you dentist for regular check and when you ask he laughs in your face." I read about steam c…

As a general rule, the entire medical profession has the incentives set up the wrong way - the more problems you have, the more they benefit. I have read that there was a time, in the distant past, where you paid a doctor only as long as you were healthy. I can come up with some problems even in that case, but I can't help but think it might still be an improvement over the current situation...

Except that it is simply not true - the world is not that simple.

There are several incentives at play for a doctor.

Obviously there are different fields, and dental is slightly weird compared to the others, but first of all, doctors are trained to help and learn cures.

A doctor that keeps you sick instead of healthy is quickly out of a job (or out of patients, if you prefer). There are other doctors you know, and there is word-of-mouth, and ratings etc. There is no world-wide conspiracy of dental workers to keep you from getting a specific cure. Aka: Game Theory.

And an easy way to get rid of this would be if the doctors would be paid to keep you healthy:

So you pay as long as you are healthy, e.g. a valuable work-force. Hmmm, I wonder if you could just use income tax to fuel this...? Oh, we just invented universal health care, didn't we?

Re: Suppressing a gene by using its antibody can lead to tooth growth: animal study

#109

Post by Black101 »

social_quotient wrote: post #86
donatj wrote: post #41

Earlier quoted context omitted.

Novamin toothpaste has been life changing for me. Cannot recommend highly enough. A tooth that was deteriorating and the dentist wanted to cap is now fine enough for them to simply keep an eye on.

I’ve had similar success with toothpastes containing “nano-hydroxyapatite” Amazon has several good ones. I also have 2 kids, the youngest (4 yr old) had cavity issues which required intervention and then we started using the hydroxyapatite toothpaste and had no issues since. I also headed down this path via looking for Novamin. I wish there was a reliable way to get it without the “is it fake” on Amazon. I’d gladly a…

I ordered some from Canada, made in Canada, using Ebay (about as reliable as Amazon but it doesn't come from India and it is cheaper).

Re: Suppressing a gene by using its antibody can lead to tooth growth: animal study

#110

Post by Guillaume86 »

mdpopescu wrote: post #94
NiceWayToDoIT wrote: post #92

Although amazing, I am following similar news for last 20 years, and promise of tooth regrowth was as a holly grail of dental health, but on the other side it is similar like a nuclear fusion always 20 years away. Process goes like this, "big news -> excitement -> and then nothing -> few years later again nothing -> you go to you dentist for regular check and when you ask he laughs in your face." I read about steam c…

As a general rule, the entire medical profession has the incentives set up the wrong way - the more problems you have, the more they benefit. I have read that there was a time, in the distant past, where you paid a doctor only as long as you were healthy. I can come up with some problems even in that case, but I can't help but think it might still be an improvement over the current situation...

It's worse than saying we should only pay devs the days there's no bugs in production, doctors can't decide to magically prevent diseases from existing or accidents to happen.
Post reply on HN