Earlier quoted context omitted.
I don't know. We see pharma companies killing one-time cures to not cannibalise recurring treatments, even if another company makes the recurring treatments.
Where have we seen this? Genuine question.
Suppressing a gene by using its antibody can lead to tooth growth: animal study
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Re: Suppressing a gene by using its antibody can lead to tooth growth: animal study
#62The article linked says it causes new teeth to grow in rats and ferrets, and that pugs and dogs are next. It doesn't however talk about targeting that growth to a particular place.
Don't rodent teeth grow continuously anyway? That's why they're always gnawing on stuff.
Yea, I remember seeing a picture on reddit years ago where a squirrel, feasting on soft human trash, his teeth didn't wear down and grew outwards in concentric circles until he presumably starved from now not being able to chew even the softest of foods. I don't want to look up the photo, it's sad, but I think it was legit.
Re: Suppressing a gene by using its antibody can lead to tooth growth: animal study
#63As long as tooth growth occurs in the right place, that sounds appealing
Re: Suppressing a gene by using its antibody can lead to tooth growth: animal study
#64Earlier quoted context omitted.
Novamin toothpaste has been life changing for me. Cannot recommend highly enough. A tooth that was deteriorating and the dentist wanted to cap is now fine enough for them to simply keep an eye on.
I have never heard of this Novamin toothpaste before. Nor has any of my dentists ever recommended it. It looks like the popular brand is Sensodyne.
Sensodyne does not have Novamin in the USA(insert conspiracy theory here). You'd either have to import it from a reputable supplier, or try an alternative like Apagard or Biomin F(both of those have to be imported too, but are more readily available).
Re: Suppressing a gene by using its antibody can lead to tooth growth: animal study
#65Earlier quoted context omitted.
I don't know. We see pharma companies killing one-time cures to not cannibalise recurring treatments, even if another company makes the recurring treatments.
Where have we seen this? Genuine question.
I don’t have a specific example of openly stopping production of a cure, but it’s hard to imagine that research isn’t shaped by this profit drive:
https://www.cnbc.com/2018/04/11/goldman-asks-is-curing-patie...
If the profit incentive was removed (let’s say government paid same flat rate for a lifetime supply of treatment, whether it be a cure or a reoccurring pill) I have no doubt more cures would be discovered
Re: Suppressing a gene by using its antibody can lead to tooth growth: animal study
#66Earlier quoted context omitted.
Novamin toothpaste has been life changing for me. Cannot recommend highly enough. A tooth that was deteriorating and the dentist wanted to cap is now fine enough for them to simply keep an eye on.
I have never heard of this Novamin toothpaste before. Nor has any of my dentists ever recommended it. It looks like the popular brand is Sensodyne.
Quick googling found a funny metastudy: "The articles from the database obtained for further review was N = 1. According to the study..."
Re: Suppressing a gene by using its antibody can lead to tooth growth: animal study
#67Earlier quoted context omitted.
Consumers would beat a path to the door of the dentists that offered this. They would make tons of money. The dentists not offering this product would lose customers and go out of business.
I don't know. We see pharma companies killing one-time cures to not cannibalise recurring treatments, even if another company makes the recurring treatments.
Yet one of the biggest selling products ever was a cure for hepatitis C.
Pharma hiding cures is internet BS.
Re: Suppressing a gene by using its antibody can lead to tooth growth: animal study
#68Whatever progress it may provide, I am certain that dentists and dentists' associations will slowly and surely entomb any process that reduces the sum of their individual annual incomes. I believe Adam Smith called it "the invisible hand" (w/o explicitly noting that the "invisible boot" is jammed into the "invisible customers"' collective asses).
It's so sad that most dentists optimise for billable revenue, even at the detriment of long term patient health. Fillings for example always degrade and need repairs after X years. Drilling and filling even the smallest cavity puts that teeth on a lifetime progression to bigger and bigger fillings, eventually a root canal, eventually an implant. Cavities, on the other hand can be arrested (stopped), and if small can…
Orthopedic surgeons do the same thing. Inject steroids repeatedly, degrading joints in order to do joint replacements. And those joint replacements aren't great, so they need to be replaced periodically.
Re: Suppressing a gene by using its antibody can lead to tooth growth: animal study
#69The article linked says it causes new teeth to grow in rats and ferrets, and that pugs and dogs are next. It doesn't however talk about targeting that growth to a particular place.
I'd just hope that the new teeth at least grow in the mouth
On my hands or on my johnson wouldn't be good.
Re: Suppressing a gene by using its antibody can lead to tooth growth: animal study
#70Some tumors can grow teeth. Wonder if this might be a related process. https://www.healthline.com/health/teratoma
Teratomas, IIRC, are often incomplete twins that failed to divide from their siblings.