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Fructose reprogrammes glutamine-dependent oxidative metabolism to support LPS

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21–30 of 110 posts

Re: Fructose reprogrammes glutamine-dependent oxidative metabolism to support LPS

#21
post #11
post #9

Earlier quoted context omitted.

If we (in the US) could end corn subsidies, use of HFCS in food production would probably fall naturally as other sweeteners were able to compete again for the cheapest sweetener.

Sugar derived from cane and beet and honey are exactly as bad for your health as high-fructose corn syrup.

.. but they would be more expensive than HFCS in the US.

Re: Fructose reprogrammes glutamine-dependent oxidative metabolism to support LPS

#22
post #16
post #13

Earlier quoted context omitted.

Honey appears to have some other beneficial properties. There is no real evidence that moderate honey consumption causes worse health outcomes.

The thing with honey is that it is rare and seasonal in nature. Once a month/season/year is probably highly beneficial, daily is likely to be a slow suicide.

Curious: Rare and seasonal how? Most honey lasts for years or decades if willing to put up with some crystallization.

All things in moderation... . A dab of honey in tea once a day can't be that many micromorts.

Re: Fructose reprogrammes glutamine-dependent oxidative metabolism to support LPS

#23
post #12

Can someone explain to me how this doesn't imply that I should completely remove fructose from the list of ingredients in food I am willing to consume?

I actually watched an interesting video on this last night by Adam Ragusea, who hosts a cooking channel and likes to dabble in the food science side of things on occasion - https://youtu.be/DEKrfvgPGDY It looks to be the case that in the case of HFCS high ratios of Fructose to Glucose can cause issues because of excess free Fructose. If the balance between the two is maintained, things may be less problematic.

HFCS is a misnomer. It's just 55% fructose and 45% glucose. Whereas sucrose is exactly 50% fructose and 50% glucose. HFCS is a health problem, but not not more so than sugar already.

Balancing free fructose does not matter because by eating starch, you are already intaking much more glucose than fructose.

Re: Fructose reprogrammes glutamine-dependent oxidative metabolism to support LPS

#24
post #16

Earlier quoted context omitted.

The thing with honey is that it is rare and seasonal in nature. Once a month/season/year is probably highly beneficial, daily is likely to be a slow suicide.

Rare and seasonal? It literally does not spoil on any timescale that matters.

Don't preppers keep it as an alternative to sugar or as a carbs calorie source?

Re: Fructose reprogrammes glutamine-dependent oxidative metabolism to support LPS

#25
post #10

Can someone explain to me how this doesn't imply that I should completely remove fructose from the list of ingredients in food I am willing to consume?

Table sugar is entirely made up of sucrose. A polymer which is composed of one glucose molecule and one fructose molecule. Fructose is also in most fruit sugars. Honey is one of the worst offenders from a natural source. Finally corn syrup is the absolute worst. Avoiding refined sugars in general is a good thing, but removing fructose completely would require not eating any fruits or berries either. The rule of thumb…

Berries have very little sugar.

https://www.healthline.com/health/best-low-sugar-fruits

Re: Fructose reprogrammes glutamine-dependent oxidative metabolism to support LPS

#26
post #11
post #9

Earlier quoted context omitted.

If we (in the US) could end corn subsidies, use of HFCS in food production would probably fall naturally as other sweeteners were able to compete again for the cheapest sweetener.

Sugar derived from cane and beet and honey are exactly as bad for your health as high-fructose corn syrup.

It's easier for people to believe that HFCS is the devil than to change their habits, which include consuming 45 gallons of soda contributing to 60lbs of sugar consumed per year. The average american consumes over 300 calories per day of just sugar. 17 teaspoons per day. Just imagine scooping that out of a bag. That's never going to be ok whether it's HFCS, table sugar, or honey.

Moving from HFCS to table sugar wouldn't change those numbers at all... but if they can blame HFCS it'll ease their guilt that they might be personally responsible for the health consequences of their own diet.

Edit: keep in mind, this is ADDED sugars only. It doesn't include natural sugars, like those found in juice, fruits, etc. The average american consumers an incredible amount of sugar.

Re: Fructose reprogrammes glutamine-dependent oxidative metabolism to support LPS

#27
post #17
post #7

The study is conducted in mouse and human immune cells in a dish, and the purported link is between HFCS and inflammation. Its also not clear to me if the concentrations of fructose used in the study reflect the dynamic range of concentrations of fructose in your tissues during day-to-day life.

A diet high in fructose is not advisable for people with an autoimmune disease. One study did that of people with a large number of specific types of autoimmune disease that can be caused by high fructose foods. This study showed that one diet was associated with a higher incidence of these autoimmune diseases in those with large and consistent levels of fructose intake. For example, in those with low body weight you…

Question: Does this mean honey and high fructose corn syrup are approximately equally [1] unhealthy? Or is honey an anomaly/enigma [2] in this respect?

[1] Apparently honey contains ~40% fructose, which about the same as “HFCS42” (a standard 42% fructose corn syrup product).

[2] I ask this because I’ve read many claims that honey is among the healthiest forms of sugar, with many studies cited that show all sorts of health benefits of honey (at least versus table sugar or HFCS). Is this pseudoscientific bunk that I’ve been mislead to believe?

Re: Fructose reprogrammes glutamine-dependent oxidative metabolism to support LPS

#28
post #10

Can someone explain to me how this doesn't imply that I should completely remove fructose from the list of ingredients in food I am willing to consume?

Table sugar is entirely made up of sucrose. A polymer which is composed of one glucose molecule and one fructose molecule. Fructose is also in most fruit sugars. Honey is one of the worst offenders from a natural source. Finally corn syrup is the absolute worst. Avoiding refined sugars in general is a good thing, but removing fructose completely would require not eating any fruits or berries either. The rule of thumb…

I think most Americans are doing just fine with high fructose diets. However, there have been a lot of studies coming out, that seem to be suggesting there is some danger of obesity after a certain low carbohydrate diet or skipping carbohydrates altogether, as these diets tend to spike blood sugar rapidly. The most interesting is a study in humans, that showed a significant increase in blood glucose when carbohydrates were restricted . However, the more I look at it the more I feel like the results are definitely not true for me. I still get a pretty nice feeling in my mouth after eating sugar but I don't notice much of a difference in taste, taste just seems dull, bland, sour, and nothing much else, other than I don't feel I need as many carbohydrates as I did before.

Re: Fructose reprogrammes glutamine-dependent oxidative metabolism to support LPS

#29

I wonder if we’ll ever see HFCs regulated like tobacco or alcohol. It’s another one of those epic scandals by huge corporations that used propaganda to sway public opinion...and now we’re left with an obesity epidemic.

A more apt comparison would be regulation of trans fats.

https://en.wikipedia.org/wiki/Trans_fat_regulation

Re: Fructose reprogrammes glutamine-dependent oxidative metabolism to support LPS

#30
post #10

Can someone explain to me how this doesn't imply that I should completely remove fructose from the list of ingredients in food I am willing to consume?

Table sugar is entirely made up of sucrose. A polymer which is composed of one glucose molecule and one fructose molecule. Fructose is also in most fruit sugars. Honey is one of the worst offenders from a natural source. Finally corn syrup is the absolute worst. Avoiding refined sugars in general is a good thing, but removing fructose completely would require not eating any fruits or berries either. The rule of thumb…

In addition to your comment, Sugar/Sucrose can be processed by your entire body. Fructose can only be processed by your liver. Consuming too much Fructose (easy to do), is not a good thing for your Liver.
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