Fructose reprogrammes glutamine-dependent oxidative metabolism to support LPS
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Re: Fructose reprogrammes glutamine-dependent oxidative metabolism to support LPS
#2I can hardly understand what this is saying. Is it merely that fructose consumption correlated with inflammation?
Re: Fructose reprogrammes glutamine-dependent oxidative metabolism to support LPS
#3I can hardly understand what this is saying. Is it merely that fructose consumption correlated with inflammation?
I read it as HFCs and juices are the smoking gun in obesity and type-2 diabetes.
Re: Fructose reprogrammes glutamine-dependent oxidative metabolism to support LPS
#4I wonder if we’ll ever see HFCs regulated like tobacco or alcohol. It’s another one of those epic scandals by huge corporations that used propaganda to sway public opinion...and now we’re left with an obesity epidemic.
Re: Fructose reprogrammes glutamine-dependent oxidative metabolism to support LPS
#5Re: Fructose reprogrammes glutamine-dependent oxidative metabolism to support LPS
#6I can hardly understand what this is saying. Is it merely that fructose consumption correlated with inflammation?
> Our results have highlighted the metabolic plasticity of human monocytes in response to fructose exposure and have elucidated the metabolic mechanisms supporting fructose-induced inflammation.
They are proposing a particular explanation for how fructose over-exposure can lead to inflammation.
Re: Fructose reprogrammes glutamine-dependent oxidative metabolism to support LPS
#7The study is conducted in mouse and human immune cells in a dish, and the purported link is between HFCS and inflammation.
Its also not clear to me if the concentrations of fructose used in the study reflect the dynamic range of concentrations of fructose in your tissues during day-to-day life.
Re: Fructose reprogrammes glutamine-dependent oxidative metabolism to support LPS
#8Can someone explain to me how this doesn't imply that I should completely remove fructose from the list of ingredients in food I am willing to consume?
Re: Fructose reprogrammes glutamine-dependent oxidative metabolism to support LPS
#9I wonder if we’ll ever see HFCs regulated like tobacco or alcohol. It’s another one of those epic scandals by huge corporations that used propaganda to sway public opinion...and now we’re left with an obesity epidemic.
If we (in the US) could end corn subsidies, use of HFCS in food production would probably fall naturally as other sweeteners were able to compete again for the cheapest sweetener.
Re: Fructose reprogrammes glutamine-dependent oxidative metabolism to support LPS
#10Can someone explain to me how this doesn't imply that I should completely remove fructose from the list of ingredients in food I am willing to consume?
Table sugar is entirely made up of sucrose. A polymer which is composed of one glucose molecule and one fructose molecule. Fructose is also in most fruit sugars. Honey is one of the worst offenders from a natural source. Finally corn syrup is the absolute worst.
Avoiding refined sugars in general is a good thing, but removing fructose completely would require not eating any fruits or berries either. The rule of thumb is that whole fruits and berries are okay if you get the plant fiber along with the juice and don't eat too many. Fruit juice drinks and refined sugars should be avoided for sure. Especially corn syrup, honey, and maple syrup.
Right now I only use refined sugar to feed yeast in baking breads. Even then, it doesn't take much. I don't drink fruit juice and only occasionally eat whole fruit as a treat. That seems to work okay so far for me, so take it as you will.