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Fructose reprogrammes glutamine-dependent oxidative metabolism to support LPS

nature.com

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Re: Fructose reprogrammes glutamine-dependent oxidative metabolism to support LPS

#11

Post by nayuki »

sprayk wrote: post #9
binarymax wrote: post #4

I wonder if we’ll ever see HFCs regulated like tobacco or alcohol. It’s another one of those epic scandals by huge corporations that used propaganda to sway public opinion...and now we’re left with an obesity epidemic.

If we (in the US) could end corn subsidies, use of HFCS in food production would probably fall naturally as other sweeteners were able to compete again for the cheapest sweetener.

Sugar derived from cane and beet and honey are exactly as bad for your health as high-fructose corn syrup.

Re: Fructose reprogrammes glutamine-dependent oxidative metabolism to support LPS

#12

Post by Tsiklon »

mikewarot wrote: post #8

Can someone explain to me how this doesn't imply that I should completely remove fructose from the list of ingredients in food I am willing to consume?

I actually watched an interesting video on this last night by Adam Ragusea, who hosts a cooking channel and likes to dabble in the food science side of things on occasion - https://youtu.be/DEKrfvgPGDY

It looks to be the case that in the case of HFCS high ratios of Fructose to Glucose can cause issues because of excess free Fructose.

If the balance between the two is maintained, things may be less problematic.

Re: Fructose reprogrammes glutamine-dependent oxidative metabolism to support LPS

#13

Post by nradov »

foxyv wrote: post #10
mikewarot wrote: post #8

Can someone explain to me how this doesn't imply that I should completely remove fructose from the list of ingredients in food I am willing to consume?

Table sugar is entirely made up of sucrose. A polymer which is composed of one glucose molecule and one fructose molecule. Fructose is also in most fruit sugars. Honey is one of the worst offenders from a natural source. Finally corn syrup is the absolute worst. Avoiding refined sugars in general is a good thing, but removing fructose completely would require not eating any fruits or berries either. The rule of thumb…

Honey appears to have some other beneficial properties. There is no real evidence that moderate honey consumption causes worse health outcomes.

Re: Fructose reprogrammes glutamine-dependent oxidative metabolism to support LPS

#15

Post by tp3 »

mikewarot wrote: post #8

Can someone explain to me how this doesn't imply that I should completely remove fructose from the list of ingredients in food I am willing to consume?

It doesn't really have anything to do with food. To learn more about this study see: http://www.ncbi.nlm.nih.gov/pubmed/15571466 Cognitive Benefits of a High Fructose Diet: I find that a diet high in simple sugars is beneficial in several aspects for cognitive performance, especially when compared to a standard diet. For example, one of the largest studies ever found that a high fructose diet was associated with an enhanced cognitive performance of young women. So, I recommend the high fructose diet to any young women who have mild to moderate cognitive problems but want to improve their memory. You can find more information here: http://cognitive.ucsd.edu/m/mzwg/cognitive-performance.html

Re: Fructose reprogrammes glutamine-dependent oxidative metabolism to support LPS

#16

Post by juskrey »

nradov wrote: post #13
foxyv wrote: post #10

Earlier quoted context omitted.

Table sugar is entirely made up of sucrose. A polymer which is composed of one glucose molecule and one fructose molecule. Fructose is also in most fruit sugars. Honey is one of the worst offenders from a natural source. Finally corn syrup is the absolute worst. Avoiding refined sugars in general is a good thing, but removing fructose completely would require not eating any fruits or berries either. The rule of thumb…

Honey appears to have some other beneficial properties. There is no real evidence that moderate honey consumption causes worse health outcomes.

The thing with honey is that it is rare and seasonal in nature. Once a month/season/year is probably highly beneficial, daily is likely to be a slow suicide.

Re: Fructose reprogrammes glutamine-dependent oxidative metabolism to support LPS

#17

Post by tp3 »

vishakad wrote: post #7

The study is conducted in mouse and human immune cells in a dish, and the purported link is between HFCS and inflammation. Its also not clear to me if the concentrations of fructose used in the study reflect the dynamic range of concentrations of fructose in your tissues during day-to-day life.

A diet high in fructose is not advisable for people with an autoimmune disease. One study did that of people with a large number of specific types of autoimmune disease that can be caused by high fructose foods. This study showed that one diet was associated with a higher incidence of these autoimmune diseases in those with large and consistent levels of fructose intake. For example, in those with low body weight you might find a higher fructose intake and thus an higher prevalence of autoimmune diseases. So, to help prevent those type of autoimmune diseases, you might need to lower your body weight and eat a low fructose diet that gives you less carbs and so on. You can find more information here: http://www.ncbi.nlm.nih.gov/pubmed/22991621

Re: Fructose reprogrammes glutamine-dependent oxidative metabolism to support LPS

#18

Post by astockwell »

nradov wrote: post #13
foxyv wrote: post #10

Earlier quoted context omitted.

Table sugar is entirely made up of sucrose. A polymer which is composed of one glucose molecule and one fructose molecule. Fructose is also in most fruit sugars. Honey is one of the worst offenders from a natural source. Finally corn syrup is the absolute worst. Avoiding refined sugars in general is a good thing, but removing fructose completely would require not eating any fruits or berries either. The rule of thumb…

Honey appears to have some other beneficial properties. There is no real evidence that moderate honey consumption causes worse health outcomes.

Just don't give it to infants under 1yo.

Re: Fructose reprogrammes glutamine-dependent oxidative metabolism to support LPS

#19

Post by germinalphrase »

juskrey wrote: post #16
nradov wrote: post #13

Earlier quoted context omitted.

Honey appears to have some other beneficial properties. There is no real evidence that moderate honey consumption causes worse health outcomes.

The thing with honey is that it is rare and seasonal in nature. Once a month/season/year is probably highly beneficial, daily is likely to be a slow suicide.

Rare and seasonal? It literally does not spoil on any timescale that matters.

Re: Fructose reprogrammes glutamine-dependent oxidative metabolism to support LPS

#20

Post by tp3 »

tyleo wrote: post #2

I can hardly understand what this is saying. Is it merely that fructose consumption correlated with inflammation?

Fructose promotes triglycerides and the formation of these fatty acids, and is linked to heart disease. The amount of fructose in your diet affects your body weight. The amount of sugar in your diet also affects your body weight. These are all factors that influence the type of fatty acids in your body that are involved in fat metabolism and heart disease. For example, the amount of fructose affects how quickly you start to store fat in your body. So, if you eat enough refined sugars to get more saturated fat, you will have more of the "carbohydrate" in your body. So, to get more saturated fat, you would need to eat more fructose. So, if you eat too much refined sugar and no fiber, your body will be less able to store energy.
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