51–60 of 77 posts
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I wonder if this would work for rabies.
Is there such a thing as dormant rabies? My impression was that most people die from rabies if they get it, so you really want to vaccinate people with any risk of getting rabies. And the vaccine is amazingly effective. (+ you can still give the vaccine once people are infected if you're fast.)
What bothers me is that every single good news coming from science has the same old "but". >It will still take a long time before these experiments lead to the first human trials And we'll never hear from them again. You betcha!
It's often the case. It's not always the case. I remember the stories during the summer. "mRNA is promising, but there never was an mRNA vaccine that made it to the market. Nobody knows if it'll work." Well, it does work. Amazingly so.
My understanding is that herpes (both HSV1 and HSV2) are not actually bad but have enormous social stigma, which is the main problem. I wonder what can be done to address that, as an alternative strategy.
I got it very early as a kid, and kids are bad at not touching their face, so I most certainly moved it from my nose to my eye at some point.
I can also get it on my nose, in my nose, my lips, forehead. So far.
My kid is now almost 3, we were very careful, but he got it a few months ago, had it 3 times in the last three weeks. It destroys our life. We have a 6 month old, it could be life threatening for the little one if they just touch. And even if only mild, explain to a 6 month old he should not scratch his patch off his face...
Hurrah for science! Hurrah for gene therapy! We are finally able to match God in creativity, and even improve the design! God/Nature was never that good anyway, we can give ourselves special powers now. Science ethics committees have discussed this, and they say its fine - we've had that discussion! Release the beast. Its not like my code is isn't perfect - I thrive when I barely have a handle on what a complicated f…
Taking charge of our evolution / genetics has always been humanities future and there is absolutely nothing wrong with eradicating disease and optimizing us however we see fit.
.. In mice. It is unknown if it will work in humans. In addition, what are the long term consequences of causing multiple DNA cuts in nerve cells that the DNA repair mechanism cannot repair? There is still a very long, long way to go.
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Yeah Sars-Cov2 is a RNA virus. RNA is far more unstable in the long term. It needs replication to survive for longer times, even if it's only at low levels. Generally in most people, the immune system can clear out the virus itself sooner or later completely. Long term symptoms come from tissue damage. Only the small group of immuno compromised people form an exception (Think HIV, organ transplants, etc). Here, the i…
Very important to address these cases though, since it is believed that this is the source of the new variants that we are seeing now. Patients infected for months on end provide an ideal darwinian environment for the emergence of immune-escape variants.
https://www.latimes.com/science/story/2021-01-30/long-term-c...
That's unrelated from my general point though. The virus is gone in almost all people reasonably quickly.
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Taking charge of our evolution / genetics has always been humanities future and there is absolutely nothing wrong with eradicating disease and optimizing us however we see fit.
Absolutely - we should do this everywhere! We should mandate in fact. Make sure that babies, the elderly, everyone have to get say, 'RNA' vaccines. Brilliant idea! What could go wrong? Nothing.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6917347/ Just reminded myself that above frome couple years back
Can we get mRNA vaccine to Herpes
Earlier quoted context omitted.
Taking charge of our evolution / genetics has always been humanities future and there is absolutely nothing wrong with eradicating disease and optimizing us however we see fit.
Absolutely - we should do this everywhere! We should mandate in fact. Make sure that babies, the elderly, everyone have to get say, 'RNA' vaccines. Brilliant idea! What could go wrong? Nothing.
‘What could go wrong?’ That’s an incredibly insulting perspective to take toward medical researchers who dedicate their entire careers to answering such questions.