My understanding is that herpes (both HSV1 and HSV2) are not actually bad but have enormous social stigma, which is the main problem. I wonder what can be done to address that, as an alternative strategy.
Mouse studies show gene therapy can cause big drop in latent herpes infections
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Re: Mouse studies show gene therapy can cause big drop in latent herpes infections
#42What bothers me is that every single good news coming from science has the same old "but". >It will still take a long time before these experiments lead to the first human trials And we'll never hear from them again. You betcha!
Look up when the electron was discovered, and how long electronics took to become a thing.
What you probably meant is the discovery of electricity.
Re: Mouse studies show gene therapy can cause big drop in latent herpes infections
#43I remember a study suggesting the Chickenpox vaccine suppresses outbreaks of HSV1 and HSV2 https://www.dovepress.com/efficacy-of-the-anti-vzv-anti-hsv3...
I wonder if that's why I've never had HSV1 despite my wife having had several outbreaks while we've been together. We aren't careful during outbreaks because I figure I'm going to get it sooner or later and we can't go weeks without kissing, but I've still never had an outbreak.
Re: Mouse studies show gene therapy can cause big drop in latent herpes infections
#44Earlier quoted context omitted.
I am baffled why you are being downvoted. While this research is very promising, it's also not hard for me to imagine a scenario where these targeted molecular "DNA scissors" do something unexpected. And while the risks of gene editing seems worth it for fatal or debilitating diseases, I don't think I'd want to be on a trial for this for a disease that is primarily an annoyance. Again, I think the research and techni…
his comment is trash and you supporting it makes you trash as well. please get up to date on how medical research is performed.
If you don't want to be banned, you're welcome to email hn@ycombinator.com and give us reason to believe that you'll follow the rules in the future. They're here: https://news.ycombinator.com/newsguidelines.html.
Re: Mouse studies show gene therapy can cause big drop in latent herpes infections
#45One could imagine this technique also working in latent reserves of coronavirus harbored by people who have become infected.
I wonder if this would work for rabies.
My impression was that most people die from rabies if they get it, so you really want to vaccinate people with any risk of getting rabies. And the vaccine is amazingly effective. (+ you can still give the vaccine once people are infected if you're fast.)
Re: Mouse studies show gene therapy can cause big drop in latent herpes infections
#46What bothers me is that every single good news coming from science has the same old "but". >It will still take a long time before these experiments lead to the first human trials And we'll never hear from them again. You betcha!
I remember the stories during the summer. "mRNA is promising, but there never was an mRNA vaccine that made it to the market. Nobody knows if it'll work."
Well, it does work. Amazingly so.
Re: Mouse studies show gene therapy can cause big drop in latent herpes infections
#47I remember a study suggesting the Chickenpox vaccine suppresses outbreaks of HSV1 and HSV2 https://www.dovepress.com/efficacy-of-the-anti-vzv-anti-hsv3...
I wonder if that's why I've never had HSV1 despite my wife having had several outbreaks while we've been together. We aren't careful during outbreaks because I figure I'm going to get it sooner or later and we can't go weeks without kissing, but I've still never had an outbreak.
I wouldn't worry about it , very likely you already had it for most of your life
Re: Mouse studies show gene therapy can cause big drop in latent herpes infections
#48God/Nature was never that good anyway, we can give ourselves special powers now. Science ethics committees have discussed this, and they say its fine - we've had that discussion! Release the beast. Its not like my code is isn't perfect - I thrive when I barely have a handle on what a complicated function does, and can't even see it!
Re: Mouse studies show gene therapy can cause big drop in latent herpes infections
#49Earlier quoted context omitted.
Ok, well maybe this thread can be a tiny part of the solution to that stigma. First off herpes comes in two primary variants: HSV-1 and HSV-2. Most humans on Earth (between 60% and 95%) have HSV-1, and it's estimated that around 16% of humans have HSV-2. Herpes is extremely common. If you want references or more info, see the wikipedia page [0]. According to the article, the researchers are currently focused on HSV-1…
Supposedly they've stopped testing for herpes most of the time because of how likely it is someone has it, how unactionable the information is, and the stress it causes.
Re: Mouse studies show gene therapy can cause big drop in latent herpes infections
#50Hurrah for science! Hurrah for gene therapy! We are finally able to match God in creativity, and even improve the design! God/Nature was never that good anyway, we can give ourselves special powers now. Science ethics committees have discussed this, and they say its fine - we've had that discussion! Release the beast. Its not like my code is isn't perfect - I thrive when I barely have a handle on what a complicated f…