One of the things they mentioned briefly in a little documentary on the making of Soul is that all of the animators work on fairly dumb terminals connected to a back end instance. I can appreciate that working well when people are in the office, but I'm amazed that worked out for them when people moved to work from home. I have trouble getting some of my engineers to have a stable connection stable enough for VS Code…
The studio internally uses PCOIP boxes, which I don't like due the added tiny delay (I'm a bit like those developers who complain about miliseconds of latency on their text editors...). Anyways, for the work for home setup, we are using NoMachine, which doesn't feel any different from the PCoIP boxes - unless if using the MacOS client, which is much laggier than the Windows or Linux versions.
Actually, I went ahead and tried installing Nomachine on Google Cloud and Amazon AWS CPU only instances, and got the same responsiveness of my studio setup. No fancy setups or gpu encoding/decoding.
So if you have a Nuke license, you can do some pretty heavy 2D vfx for about 1USD/hour on a 96vcpu machine (performance similar to an AMD 32core) and 196GB of RAM, even without any GPU acceleration.