581–590 of 766 posts
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How so? It's a body of land surrounded by a body of water!
The United Kingdom is made up of the island of Great Britain and a part of the island of Ireland (Northern Ireland). It also includes many other smaller islands You're probably thinking of Great Britain by itself, which is the island containing the main parts of the countries of Scotland, England, and Wales.
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The UK is not an island.
How so? It's a body of land surrounded by a body of water!
https://www.forbes.com/sites/barrycollins/2020/11/15/amazon-...
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With regards to mRNA, mRNA is a fragile molecule that is quickly broken down inside the body after injection, so there's unlikely to be much long term risk with mRNA itself.
Holy jeeze. This is why we have the FDA. The extent to which a molecule is active in your body is only slightly correlated with toxicity. There is zero reason why a fragile molecule can't cause damage before it breaks down. This is how ended up with thalidomide. They tested it in pregnant lab rats, but the window for birth defects is incredibly short in rats. So everything checked out. In drug development you can't a…
The FDA at this point certainly doesn't have the ability to analyze that either, so the best we have is a theoretical understanding.
In terms of rollout. UK is the ideal country to be the first: 1. Heavily impacted by Covid-19. 2. Centralised health care system makes it easier to compare results and efficiency. E.g. it's UK which figured out that dexamethasone is efficient against Covid https://www.who.int/news/item/16-06-2020-who-welcomes-prelim... 3. Developed country with great logistics.
4. Is an island that can be cut off incase of a zombie apocalypse...
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4. Is an island that can be cut off incase of a zombie apocalypse...
Great with comments like this the site is now basically worthless reddit
> Please don't post comments saying that HN is turning into Reddit. It's a semi-noob illusion, as old as the hills.
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The United Kingdom is made up of the island of Great Britain and a part of the island of Ireland (Northern Ireland). It also includes many other smaller islands You're probably thinking of Great Britain by itself, which is the island containing the main parts of the countries of Scotland, England, and Wales.
So the UK is an archipelago?
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How could numbers in a "controlled" trial be valid if they are arrived at by accident?
The half dose was an 'experimental endpoint'. Always planned but not seen as critical. FDA rules now stipulate you can only register on primary endpoints declared before the trial starts. I suspect AZ have argued that the accelerated nature of the process should take this into account.
[1] https://clinicaltrials.gov/ct2/show/NCT04516746 [2] https://www.reuters.com/article/uk-health-coronavirus-astraz...
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I don't want to have to be sober to drive my car on public roadways, and yet, here I am, acknowledging that I have some basic responsibility for the safety of people around me. This approach is incredibly selfish. Would you pursue it if you were held responsible for consequences of that behaviour, as drunk drivers are?
This is a bad argument. The two aren't comparable. Drinking a lot of alcohol and getting into a car is a choice. The intent doesn't even matter in most countries since it's a "Strict liability" crime. The government forcing you to take an injection is literally not your choice. Not to mention, we know drunk driving impairs people and increases risk. There are tons of studies that show that (they also show sleep depri…
Not taking a vaccine and interacting with other people is also a choice.
> they also show sleep deprivation is worse than alcohol for driving, but that's not illegal
Drowsy driving is difficult to prove, but generally held to be within the coverage of reckless driving laws. Some jurisdictions have expressly included coverage of it, as well, at least in the context of establishing the necessary illegality in vehicular homicide statutes (NJ and Arkansas.)
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> the press releases claim that they are similar to what is typical of other vaccines. They are much, much, worse but typically subside in a day and at most two. The side effects are bad enough that there is worry people won't show up for the second dose. Still going to have it, myself.
What is your source on this?
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Smartphone mobility and social graph data that’s already being collected and analyzed. Rather than just using existing tech to target ads and build surveillance capitalism profiles, it could be used in the public interest. On an opt in basis naturally; but as frictionlessly as possible via cookie tracker popups and updates to FAANG terms of service perhaps.
"Based on tracking your GPS and behavior on Facebook, we need you to come in for an injection." Where do I sign up?!