Earlier quoted context omitted.
*Shortened phase 3 trials.
I'd be happy to know how that shortening affects confidence in the vaccine.
Efficacy confidence isn't affected, but side effect confidence is.
Pfizer Covid vaccine approved for use next week in UK
381–390 of 766 posts
Re: Pfizer Covid vaccine approved for use next week in UK
#382Some elderly friends have asked why Britain is opting to use a brand new RNA/nanotechnololgy style vaccine (which has never been approved before) and is only ~94% effective, when there is a traditional inactivated vaccine that is 100% effective? I presume Pfizer simply have better lobying, but given the choice, I would rather go with old-fashioned sinovac https://www.thelancet.com/journals/laninf/article/PIIS1473-3...
Re: Pfizer Covid vaccine approved for use next week in UK
#383Earlier quoted context omitted.
There may be places you won't be allowed to go and things you won't be allowed to do (like work, maybe) unless you show proof of having been vaccinated. The UK government has ruled out having a vacination passport (for good reason in my opinion).
The UK government had also ruled the second national lockdown, but here we are. Is there a counter since the last U-turn of the UK government?
This isn't a fair comparison, or reasoned in good faith.
The UK government changed their mind about a second lockdown given new evidence. The virus got much worse and they responded. What new evidence is there that the UK government is going to start vaccination passports? Has something changed?
Re: Pfizer Covid vaccine approved for use next week in UK
#384This isn't "fast" we just have low expectations of our government. The FDA in the US is taking 3 weeks to reviews, about 5-10% of the entire time to develop this is just to schedule this (3rd to last) meeting. All while over a thousand people die per day (so during this waiting period something like 10x the lives of 9/11). We just spent 9 months trying to lift the ban on this vaccine. We have the technology to beat p…
This is so much oversimplification that it hurts.
1) BioNTech/Pfizer haven't "just" tested for safety (I'm implying that's what you meant with your "trying to lift the ban" hyperbole), they have also used the clinical trials to single out one particular candidate out of at least four initial candidates for best expected efficacy. And they have used the trials to evaluate the best dosage. Medical trials are about much more than just the safety aspect.
2) It's easy to say "we could simply have broadly distributed this vaccine back in March" now in hindsight. However, in March, there were serious doubts about whether it would even work, considering the entire technology hadn't ever yielded a fully approved commercial vaccine.
3) I don't want to highlight this once more, but COVID-19 wouldn't be so deadly if the US hadn't fucked up its response in every possible way, and some that were thought to be impossible. A good part of those "over a thousand people dying per day" are self-inflicted and have nothing to do with any vaccine tests or vaccine approval timelines.
Re: Pfizer Covid vaccine approved for use next week in UK
#385Earlier quoted context omitted.
I'm concerned about that, but I'm far more concerned about covid-19, so I would be pretty happy to take a vaccine. Covid is known to have risk of death, side-effects, and unknown future medical conditions, so it seems unlikely that a vaccine would be much worse than that.
Nearly all of the things you mentioned is among old or obese people. Lucky children can't vote, lets start vaccinations! I somewhat kid, but COVID is a real life example where a tiny minority has ruled over the overwhelming majority.
It just old and sick people dying, don't worry about it!
Re: Pfizer Covid vaccine approved for use next week in UK
#386Some elderly friends have asked why Britain is opting to use a brand new RNA/nanotechnololgy style vaccine (which has never been approved before) and is only ~94% effective, when there is a traditional inactivated vaccine that is 100% effective? I presume Pfizer simply have better lobying, but given the choice, I would rather go with old-fashioned sinovac https://www.thelancet.com/journals/laninf/article/PIIS1473-3..…
> only ~94% effective
Lol.
Re: Pfizer Covid vaccine approved for use next week in UK
#387Earlier quoted context omitted.
I'm concerned about that, but I'm far more concerned about covid-19, so I would be pretty happy to take a vaccine. Covid is known to have risk of death, side-effects, and unknown future medical conditions, so it seems unlikely that a vaccine would be much worse than that.
Nearly all of the things you mentioned is among old or obese people. Lucky children can't vote, lets start vaccinations! I somewhat kid, but COVID is a real life example where a tiny minority has ruled over the overwhelming majority.
Don’t know where you are, but in the UK and the US, old and/or obese is nothing like a tiny minority.
Re: Pfizer Covid vaccine approved for use next week in UK
#388Earlier quoted context omitted.
> Even when people in the UK should be celebrating, as literally the first country in the world to develop an approved C19 vaccine in record breaking time The UK has one of the first (Oxford/AstraZenica), but this news about the first approved is not a vaccine developed in the UK. But I'm still happy to celebrate the Turkish couple's German company that's owned by Pfizer, as I will be when Oxford hopefully release mo…
It's strange how we immediately take pride in stuff we had nothing to do with just because we identify in some way with the developers/creators.
Isn't it essentially the same human instinct that drives the desire to increase representation in media for underrepresented groups of people? We relate to people who are "like us" in some dimension. Sure, it doesn't make sense in a sterile intellectual sort of way, but why does that matter? It's still real.
Re: Pfizer Covid vaccine approved for use next week in UK
#389Earlier quoted context omitted.
We all are still waiting peer-reviewd scientific papers instead of press releases....
Sorry, do you think the UK regulator approved Pfizer based on... a press release?
The full data was just released like last week? There hasn’t been time to fully review it which may be the point.
The US set a meeting date of 12/10 to decide on EUA so scientists had time to review the data.
Re: Pfizer Covid vaccine approved for use next week in UK
#390Earlier quoted context omitted.
*Shortened phase 3 trials.
I'd be happy to know how that shortening affects confidence in the vaccine.
20% points seems to be the drop as the rapid approval process became a victim hyper-partisanship in the US. The push for a rapid approval has been viewed, by the left, as a political ploy by the right instead of a well-planned & scientifically supported approval process. Early polls about taking a vaccine showed much higher support for it before it was politicized. [0]
Support dropped by 20%. Surprisingly, it dropped by about the same amount for both the political right & left, although support on the left started at a higher level. This may indicate that even people on the right were influenced by the perception of a too-rapid approval process.
[0] https://www.pewresearch.org/science/2020/09/17/u-s-public-no...