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Pfizer Covid vaccine approved for use next week in UK

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Re: Pfizer Covid vaccine approved for use next week in UK

#341

Earlier quoted context omitted.

There may be places you won't be allowed to go and things you won't be allowed to do (like work, maybe) unless you show proof of having been vaccinated. There's a good chance that situation will create a black market both for vaccines (real and fake) and forged proof of vaccination.

There may be places you won't be allowed to go and things you won't be allowed to do (like work, maybe) unless you show proof of having been vaccinated. The UK government has ruled out having a vacination passport (for good reason in my opinion).

The UK government had also ruled the second national lockdown, but here we are. Is there a counter since the last U-turn of the UK government?

Re: Pfizer Covid vaccine approved for use next week in UK

#342
post #42

Earlier quoted context omitted.

Not sure why you’re downvoted - it’s a legit question.

No, it's the typical gish gallop of "skeptics". Swamp others with questions you could easily answer yourself if your intent were honest inquiry rather than making something/someone look bad.

A skillful display of ad hominems. It's a shame to see your talent wasted on an arena as HN, when twitter would appreciate it so much more.

Re: Pfizer Covid vaccine approved for use next week in UK

#343
post #331

In terms of rollout. UK is the ideal country to be the first: 1. Heavily impacted by Covid-19. 2. Centralised health care system makes it easier to compare results and efficiency. E.g. it's UK which figured out that dexamethasone is efficient against Covid https://www.who.int/news/item/16-06-2020-who-welcomes-prelim... 3. Developed country with great logistics.

In a recent article about the Moderna vaccine, it was mentioned that the actual development only took 2 days.... and it was done in January! Given how short of a time it took to actually develop this thing, could we have drastically sped up this process by maybe being a bit more risky with the trials? At this point ~1.5 million people have died from the virus. I've really struggled with this knowledge that we've had…

There are 321 vaccine candidates under development as of September with about 30 in clinical trials. Throughout the year there were probably many, many hundreds or thousands more discarded at early stages of development and evaluation. How would you have selected this particular candidate over all the other possibilities that got dropped?

Re: Pfizer Covid vaccine approved for use next week in UK

#344

Earlier quoted context omitted.

Medical isn't constrained to science. Healthcare professionals are allowed to use tradition, authority, and Art in combination with science. It's mind boggling to Engineers to hear this, but Medicine is older than the scientific method and physicians used Regulatory capture to prevent competition. I'd love a science based healthcare alternative.

Science doesn't have all the answers. My partner recently got into a heated debate with a pharmaceutical company she was working for because they wanted something added to their standards of care document for a rare genetic disorder they developed a therapy for. She couldn't find a study to backup the claims that the medical team wanted to make in the document, but the lead doctor said that if this wasn't included, t…

Is the issue that the doctor didn't make records of their patients? It sounds like they have data.

Formal Peer review is good, but not necessary in science. Replication is necessary.

And as a note, we can still have Authority based healthcare, but a science based healthcare system would be cheaper and more reliable.

Re: Pfizer Covid vaccine approved for use next week in UK

#345
post #20

Not sure why the posts asking for vaccine risks are getting downvoted. Pandemrix, the vaccine for swine flu, caused a notable amount of narcolepsy cases in recipients here in FIN (notable here meaning the amount of yearly cases spiked by 3-4x) and as with anything that's taken quick to market there has to be some risk of overlooking some tail events somewhere. It's not an anti-vaccine attitude, just healthy skepticis…

Healthy skepticism belong in peer-reviews, in revisions of medical journals. Skepticism in the public space fosters anti-vaccine sentiments, adds to the already growing anti-vax movements and puts in risk the vulnerable in our society as they require shielding and for the rest of us to do our part.

Remember the food pyramid (that said you should eat more carbs than any other category) which was published by the medical experts?

Re: Pfizer Covid vaccine approved for use next week in UK

#346

In terms of rollout. UK is the ideal country to be the first: 1. Heavily impacted by Covid-19. 2. Centralised health care system makes it easier to compare results and efficiency. E.g. it's UK which figured out that dexamethasone is efficient against Covid https://www.who.int/news/item/16-06-2020-who-welcomes-prelim... 3. Developed country with great logistics.

Happy beta testing to all Brits then!

It's already been beta tested. That's the point of Phase 3 trials.

Re: Pfizer Covid vaccine approved for use next week in UK

#347
post #305
post #151

Earlier quoted context omitted.

My understanding is that that trial condition (half->full) was administered accidentally (thus not pre-registered) and nobody expected it to work better, and the sample size is small and on the wrong age groups.

This doesn't matter though. The results are still valid.

How could numbers in a "controlled" trial be valid if they are arrived at by accident?

Re: Pfizer Covid vaccine approved for use next week in UK

#348

Serious question: if you're a young person with no health issues, should you even get the vaccine?

No. You cannot seriously belive such a rushed vaccine has been tested properly. If you're young you will get natural immunity from it sooner or later. No young person had any issues. More young people will be hurt by the vaccine than COVID.

> No young person had any issues.

This isn't true. In my country we've had 25-35 deaths in people under 45 from Covid-19. So the death rate is very very small, but its not zero.

Including deaths of people under 25. These people may have had existing co-morbidities of course, but not all of them might have known they had those co-morbidities.

A lot of hospitalizations of people under 45 too.

Re: Pfizer Covid vaccine approved for use next week in UK

#349

Earlier quoted context omitted.

Medical isn't constrained to science. Healthcare professionals are allowed to use tradition, authority, and Art in combination with science. It's mind boggling to Engineers to hear this, but Medicine is older than the scientific method and physicians used Regulatory capture to prevent competition. I'd love a science based healthcare alternative.

Science doesn't have all the answers. My partner recently got into a heated debate with a pharmaceutical company she was working for because they wanted something added to their standards of care document for a rare genetic disorder they developed a therapy for. She couldn't find a study to backup the claims that the medical team wanted to make in the document, but the lead doctor said that if this wasn't included, t…

I'm sure many, including myself, have experienced this issue very personally and tragically. Both parties were correct in your example. In my case I was the patient advocate and would argue very strongly on the side of the doctor. Your partners case has merit as well, however, as malpractice insurance and lawsuits are impacting healthcare costs and risk management decisions considerably.
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