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Pfizer Covid vaccine approved for use next week in UK

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Re: Pfizer Covid vaccine approved for use next week in UK

#301

This isn't "fast" we just have low expectations of our government. The FDA in the US is taking 3 weeks to reviews, about 5-10% of the entire time to develop this is just to schedule this (3rd to last) meeting. All while over a thousand people die per day (so during this waiting period something like 10x the lives of 9/11). We just spent 9 months trying to lift the ban on this vaccine. We have the technology to beat p…

Isn't this the first mRNA vaccine ever approved for use?

Re: Pfizer Covid vaccine approved for use next week in UK

#302
post #98

In terms of rollout. UK is the ideal country to be the first: 1. Heavily impacted by Covid-19. 2. Centralised health care system makes it easier to compare results and efficiency. E.g. it's UK which figured out that dexamethasone is efficient against Covid https://www.who.int/news/item/16-06-2020-who-welcomes-prelim... 3. Developed country with great logistics.

> Developed country with great logistics. Please don't under-estimate our ability to fuck this up, probably by giving the distribution contracts to a crony.

Even if we are looking at things that glumly, their voters are the most vulnerable to covid. They'll be on this like butter on toast.

Re: Pfizer Covid vaccine approved for use next week in UK

#303

I had COVID-19 early in the year, and so did my Wife (not sure about my Daughter, harder to tell with kids). I would really like to know whether I should get the vaccine or not? All the info that's out there says that immunity to C19 is temporary, so a vaccine after having gone through it doesn't seem redundant. Does anyone know if there's been any research on effects of the vaccine on the people who got C19 and reco…

From the CDC: "People who have gotten sick with COVID-19 may still benefit from getting vaccinated. Due to the severe health risks associated with COVID-19 and the fact that re-infection with COVID-19 is possible, people may be advised to get a COVID-19 vaccine even if they have been sick with COVID-19 before." https://www.cdc.gov/coronavirus/2019-ncov/vaccines/vaccine-b... .

>Some early evidence suggests natural immunity may not last very long.

Doesn't the evidence so far suggest the exact opposite?

Re: Pfizer Covid vaccine approved for use next week in UK

#304

Earlier quoted context omitted.

Scotland seems to be using the Army to help plan the logistics side of things - don't know if this applies to the rest of the UK (I hope it does!): https://www.thetimes.co.uk/article/coronavirus-in-scotland-a...

The Ministry of Defence was heavily involved in the logistics planning and execution for the mobile testing units across England and Wales.

Yes the British MOD has a record of being very good at logistics [1]

"One country that has achieved an unparalleled level of efficiency and responsiveness in its logistics and sustainment activities is the United Kingdom (UK). The British Ministry of Defense (MOD) has wholeheartedly embraced outsourcing many of these functions to the private sector."

Also of interest: "One of the primary reasons why the MOD is willing and able to enter into long-term PBL-based service and support contracts with private companies, not just British firms but global providers, is because of its attitude towards the private sector. The MOD views the private sector as a positive contributor to their mission. It works hard to establish a collaborative relationship. MOD officials are demanding and insist on adherence to contracting requirements. But they treat the private companies as partners, not adversaries."

[1] https://nationalinterest.org/blog/the-buzz/britains-innovati...

Re: Pfizer Covid vaccine approved for use next week in UK

#305

Earlier quoted context omitted.

Science doesn't have all the answers. My partner recently got into a heated debate with a pharmaceutical company she was working for because they wanted something added to their standards of care document for a rare genetic disorder they developed a therapy for. She couldn't find a study to backup the claims that the medical team wanted to make in the document, but the lead doctor said that if this wasn't included, t…

Is the issue that the doctor didn't make records of their patients? It sounds like they have data. Formal Peer review is good, but not necessary in science. Replication is necessary. And as a note, we can still have Authority based healthcare, but a science based healthcare system would be cheaper and more reliable.

[deleted]

Re: Pfizer Covid vaccine approved for use next week in UK

#307
post #166
post #139

Earlier quoted context omitted.

We had excellent Public Health test and trace departments who had a wealth of experience of tracing people for sexual health purposes. But we still chose to give the contract to Dido Harding despite her poor record at NHS Improvement. And I saw what happened to NHS Logistics, which was one bit of the NHS that wasn't losing money. It was running well. It was privatised to DHL in 2006 for purely ideological reasons, an…

From a high level overview and global perspective, what the OP is saying, or meant , is that comparatively speaking UK is much better than possibly 80% of developed countries. Not to say NHS is without flaws, far from it. But if you step outside and look around the world many are surprised how awful public health services and logistics can be. So to put it another way, It is not that NHS is good, it is just the other…

Yep, sure. But we said that about pandemic preparedness and yet here were are with a minimum of 60,000 excess deaths.

Re: Pfizer Covid vaccine approved for use next week in UK

#308
post #98

Earlier quoted context omitted.

> Developed country with great logistics. Please don't under-estimate our ability to fuck this up, probably by giving the distribution contracts to a crony.

I'm sure logistics will be sold to a friend of the tories whose company assets consist of a single computer

See my previous comment about this [1]

If the private company does a good job does it matter that they are mates with a tory? Seems little short-sighted of you if I must say.

[1] https://nationalinterest.org/blog/the-buzz/britains-innovati...

Re: Pfizer Covid vaccine approved for use next week in UK

#310
post #71

Out of curiosity, how do people on HN rate the risk of long term side-effects?

I’m not aware of any vaccine that had long term side effects that were not also apparent in the short term.

E.g. I believe it was the swine flu vaccine that caused narcolepsy in a small percentage of people receiving it. But that was apparent immediately.

To my knowledge no one has identified any slow acting consequences of a vaccine that would not have been obvious from the first rollout of a vaccine.

So this question is mostly academic. Unless you’re someone in the UK slated to get the first dose, you probably won’t even have an opportunity to get the vaccine before the effects in early groups become known. And for those in high risk early groups, the risk of covid surely outweighs the risk of vaccine.

Nothing has shown up in trials so far so I’m not expecting side effects beyond the known effect of short term flu like symptoms for a couple days.

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