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Pfizer Covid vaccine approved for use next week in UK

bbc.com

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Re: Pfizer Covid vaccine approved for use next week in UK

#191

Post by polytely »

tinus_hn wrote: post #171
polytely wrote: post #78

Earlier quoted context omitted.

From what I remember from the news yesterday the EMA will be done with the evaluation (if they don't find anything that causes concern) by the end of the month, so they aren't that far off

Yeah, there’s only about 5000 deaths extra for each day of delay. So no rush there!

If people don't trust that the vaccine is safe, they will not take it, which will basically throw away a year of vaccine development and lower trust in vaccines in general and prolong the pandemic.

Re: Pfizer Covid vaccine approved for use next week in UK

#192

Post by tonyedgecombe »

ulrikrasmussen wrote: post #158
mystcb wrote: post #95

Earlier quoted context omitted.

UK Gov originally published this as the priority interim list [1] - * older adults’ resident in a care home and care home workers * all those 80 years of age and over and health and social care workers * all those 75 years of age and over * all those 70 years of age and over * all those 65 years of age and over * high-risk adults under 65 years of age * moderate-risk adults under 65 years of age * all those 60 years…

In Denmark where I live, a large proportion of infected people are age 20-29, and I wonder if it would make sense to vaccinate them first when you get to "rest of the population". Even though they have a smaller risk of getting seriously ill, that could be an effective way to lower transmission. That is: 1. Immunize the age group that is dominating in the hospitalization statistics, then 2. Immunize the age group is…

I have a suspicion that once the vaccine rolls out and is working then everybody will throw caution to the wind. It’s going to be interesting to watch this unfold.

Re: Pfizer Covid vaccine approved for use next week in UK

#193

Post by swarnie_ »

apsec112 wrote: post #107
DanBC wrote: post #101

Earlier quoted context omitted.

> Developed country with great logistics. Please don't under-estimate our ability to fuck this up, probably by giving the distribution contracts to a crony.

I'm sure the UK is in the top twenty countries in the world for logistics infrastructure. It's easy to read news stories about your country messing things up, and quietly not read foreign-language media about poorer countries messing things up a lot more by comparison, and get a biased perspective.

OP appears to have got lost on the way to /r/unitedkingdom where similar comments are generated by angry bots all day, every day.

Some perspective would be nice.

When you tell your buyers to go grab every last bit of PPE they can and cut them a blank cheque to do it of course you're not going to get the best price, especially when every other country in the world is doing the same things.

Do you focus on the 10s of millions of pieces delivered successfully? Absolutely not, get the tinfoil and red yarn out, we'll dig up something questionable. I've seen some other countries equipping medical staff in bin liners and gaffer tape, on reflection we have it pretty good.

Re: Pfizer Covid vaccine approved for use next week in UK

#194

Post by pfranz »

ijidak wrote: post #83

> It is a new type called an mRNA vaccine...An mRNA vaccine has never been approved for use in humans before, although people have received them in clinical trials. Wait... This doesn't scare anybody? Why has this not been approved before? Would an mRNA vaccine be approved under less pressing circumstances...?

I wouldn't focus too much on that--at least for yourself. You won't necessarily get an mRNA vaccine. The first two vaccines are mRNA based, but there are a bunch of others right behind it that aren't. The Oxford vaccine isn't and cheaper to produce. Since the Pfizer vaccine has all of the logistical issues with temperature storage (it not only has to be transported at -20 degrees F, it has to come to room temp before injecting) it will probably only get used at designated sites for people with higher priority. I heard someone say most non first-world countries likely won't bother with the Pfizer vaccine at all.

I believe Pfizer and Moderna are mRNA based vaccines. The Oxford and Russia's Sputnik V are adenovirus vector vaccine.

https://www.vox.com/2020/8/13/21359025/coronavirus-vaccine-c...

Re: Pfizer Covid vaccine approved for use next week in UK

#196

Post by qz2 »

pmoriarty wrote: post #23
qz2 wrote: post #2

Does anyone have any non-press infested material about this vaccine? As far as I’m aware this is the first roll out of an mRNA based vaccine. While I’m no anti vaccination idiot I’d like to understand the risks to some degree.

My go-to resource for educated COVID-19 coverage has been This Week in Virology [1], which usually has between 4 and 6 virologists reporting and analyzing COVID-19-related news every week. I've kind of OD'ed on COVID-19 news myself, so haven't listened to them for a while and don't know if they've commented on this vaccine yet, but they probably will, and for a thorough, educated, hype-free analysis, there's no bette…

Thanks - this is perfect!

Re: Pfizer Covid vaccine approved for use next week in UK

#197

Post by bojan »

tinus_hn wrote: post #171
polytely wrote: post #78

Earlier quoted context omitted.

From what I remember from the news yesterday the EMA will be done with the evaluation (if they don't find anything that causes concern) by the end of the month, so they aren't that far off

Yeah, there’s only about 5000 deaths extra for each day of delay. So no rush there!

I am fine with the thoroughness being applied. If they get it wrong the consequences may be much worse.

Re: Pfizer Covid vaccine approved for use next week in UK

#198

Post by andybak »

makomk wrote: post #53
mantap wrote: post #43

Earlier quoted context omitted.

The UK has a vaccine rollout plan that involves starting with health workers and over 80s. Due to supply issues, only those with the highest risk of death from COVID will get this vaccine.

UK health care workers were one of the main groups affected by Pandemrix-related narcolepsy. It was a bit of a scandal over here, though perhaps not the most well-known one.

I thought it would be useful to dig out some numbers here:

https://en.wikipedia.org/wiki/Pandemrix

> The increased risk of narcolepsy due to vaccination was 1 in 18400 or 0.005%

https://www.nhs.uk/news/cancer/swine-flu-deaths-examined/

seems to state an infection fatality rate of the 2009 H1N1 of 0.026%

Re: Pfizer Covid vaccine approved for use next week in UK

#199

Post by qz2 »

kolinko wrote: post #40
b112 wrote: post #24

Earlier quoted context omitted.

An immediate "but if it breaks down fast, how can it do anything?" thought springs to mind. I know what you mean is "not dormant and doing something for months/years", but at the same time, if it can initiate a modification of immune response, it can do "other things". I believe we must take the utmost of care at this juncture, and make sure assurances are not construed as in a poor light.

For me the most convincing argument regarding safety is that mRNA vaccines essentially do the same thing that the virus does, just extremely limited in scope (producing just one protein instead of a bunch of them, and not reinfecting more cells). So, even if producing the proteins turns out to be somewhat harmful long term, it cannot possibly be as harmful as the whole virus. Assuming that covid infection is inevtabl…

That's an interesting perspective. I've actually had the virus. I'm interested to see what the differential outcome of having the virus and having the vaccination is.

Re: Pfizer Covid vaccine approved for use next week in UK

#200

Post by swarnie_ »

VBprogrammer wrote: post #131
apsec112 wrote: post #107

Earlier quoted context omitted.

I'm sure the UK is in the top twenty countries in the world for logistics infrastructure. It's easy to read news stories about your country messing things up, and quietly not read foreign-language media about poorer countries messing things up a lot more by comparison, and get a biased perspective.

It's a fairly stereotypical British trait to be self deprecating. If we were singlehandedly saving the world from a rogue asteroid the general sentiment would probably be "let's hope we don't mess this up".

Lots of people in the UK (UK internet) are still not over the loss of Papa Corbyn, everything is dark and corrupted to them.
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