Is there any way for me to actually try this in the USA?
New study finds psilocybin greatly and quickly relieves depression
121–130 of 201 posts
Re: New study finds psilocybin greatly and quickly relieves depression
#122Earlier quoted context omitted.
The nice thing about ketamine is that it is a sedative. I've done LSD, Mushrooms, and DMT. Ketamine is the most enjoyable and least risky in my opinion, due to its sedative nature. The doctors usually give an anti-anxiety drug before starting the infusion, a benzodiazepine such as midazolam. As I did more infusions, we increased the ketamine dose and decreased the midazolam. Find a good doctor and work with them. Ket…
Did insurance cover Spravato? I didn’t even realize it was available as a self-administered prescription drug.
You are right: Spravato has to be administered in office, it cannot be taken home. The doctors who were offering it weren't even covered by my insurance, so I'm not sure if the drug itself is covered.
Re: New study finds psilocybin greatly and quickly relieves depression
#123As hopeful as I am for unconventional drugs to have more medicinal uses, is it unreasonable for me to think there's no good medicinal depression cure? Is it unfounded to think depression generally has its roots in being disconnected from other people/society? I've felt depressed before, but I've probably never had it as bad as many people. But generally I've felt depressed when my life felt too narrow. When I've felt…
Apparently, SSRIs work really well for some people. I know a person who is night and day difference on them. She was crying a lot and sluggish without them, down right jolly with them.
As far as the default mode network, I've seen research that claims hyperactivity of the DMN causes rumination, which puts you in a downward spiral. So perhaps a bit of inhibition is good.
Re: New study finds psilocybin greatly and quickly relieves depression
#124Link to actual study: https://jamanetwork.com/journals/jamapsychiatry/fullarticle/... Many people only read the headlines and assume that psilocybin is treating depression. The reality is that these studies psilocybin as an adjunct to 11 hours of traditional therapy. These studies aren't showing that psilocybin is a promising treatment for depression. They're showing that psilocybin-assisted therapy is a promising tr…
As someone with experience with both therapy and psilocybin (while severely depressed), I would guess the psilocybin is the main ingredient in this concoction, and the therapy is just being added to make the study more palatable, the same way medical cannabis use had to precede recreational cannabis use.
Re: New study finds psilocybin greatly and quickly relieves depression
#125Survivor bias alert; as someone who cured themself of clinical, multi-year depression with one, self-administered dose of Psilocybin in 2005... this is real. This can work. And I will never, ever take Psilocybin again.
Would you be willing to share more about this? What was your experience? Why will you never take it again? How do you think it cured your depression?
Some experiences are not fit for words, so I won’t attempt to share my experience. I do not recommend you take an unguided, illegal street dose of psilocybin. Guided, therapeutic delivery is surely more effective. Still, I believe the affects were profound, terrifying, enlightening and Most importantly lasting, 15 years in my case. I think the studies do a better job justifying the science of efficacy.
Instead I will say those that struggle, first get your sleep, diet, work and community/relationships in order. Wellness is comprehensive and this tool is better viewed as a spirit guide than a magical cure.
Re: New study finds psilocybin greatly and quickly relieves depression
#126I read "How to change your mind" last year and I tried this. It worked very well. As many studies indicate, it temporarily disables/decreases DMN (among other effects) which is exactly what a depressed person would need: break the vicious self-destructive circle. Only then I could start making hard but necessary decisions and change my life completely. Depression is nowhere to be seen but that's because I actually ch…
Note that depression is a highly variable disorder, and not every depressed person is in any kind of "vicious self-destructive circle".
Re: New study finds psilocybin greatly and quickly relieves depression
#127Is there any way for me to actually try this in the USA?
it's currently decriminalized in Oakland and probably other cities.
there are grow kits you can buy to ensure you're getting the real deal. shroomery.org probably can help you out
I think the therapy portion of this is crucial. I've heard stories of "underground" psilocybin therapists, but finding them would take some sleuthing.
Re: New study finds psilocybin greatly and quickly relieves depression
#128Earlier quoted context omitted.
You’re describing situational depression. A lot of people have chronic depression, where he only hope for managing the depression involves pharmaceuticals.
*clinical depression which could easily stem from long-term, chronic situational depression, life circumstances, etc.
> clinical depression which could easily stem from long-term, chronic situational depression, life circumstances, etc.
It could as easily not stem from it.
Re: New study finds psilocybin greatly and quickly relieves depression
#129Really sick of these "drugs feel good" stories. If we were still behaviorists, we wouldn't pretend this was news. This is declaring a full remission of depression after four weeks in half of the subjects. This is pretend science, I absolutely guarantee that an all expenses paid weeklong camping trip (or trip to Paris for those afraid of bugs, or trip to Japan for those sick of Paris) would do the same thing. Asking d…
a mushroom trip isn't always fun. it's exhausting. But you usually feel good afterwards.
So these substances aren't like coke or heroin where it's bliss and euphoria while on them (though that can happen, too)
Re: New study finds psilocybin greatly and quickly relieves depression
#130Really sick of these "drugs feel good" stories. If we were still behaviorists, we wouldn't pretend this was news. This is declaring a full remission of depression after four weeks in half of the subjects. This is pretend science, I absolutely guarantee that an all expenses paid weeklong camping trip (or trip to Paris for those afraid of bugs, or trip to Japan for those sick of Paris) would do the same thing. Asking d…
I can absolutely guarantee that when I was severely depressed, an all expenses paid weeklong camping trip would have:
- Not been enjoyable, as I was much less capable of feeling pleasure/joy
- Been way to difficult for me to accomplish, given that getting out of bed and showering was often too difficult for me to accomplish
- Would have had a negative effect on my depression