The gut is home to 70 to 80 percent of the immune cells in the body. It seems to me when you give it a break from a constant influx of food, that potentially frees up immune cells to do other things for a bit.
Intermittent fasting from dawn to sunset induces anticancer response
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Re: Intermittent fasting from dawn to sunset induces anticancer response
#12Earlier quoted context omitted.
They're only fasting for a month out of the year.
The duration in the article is 4 months. The real issue is small sample size. (14 people)
That's a really small sample size. Are they allowed to publish a study like this for such a small sample? Does anyone know if there is a minimum threshold size?
Re: Intermittent fasting from dawn to sunset induces anticancer response
#13By “no drinking”, do they really mean no drinking plain water? 14 hr stretches are doable but it’s interesting to find your body improving while becoming dehydrated.
Re: Intermittent fasting from dawn to sunset induces anticancer response
#14Noted elsewhere in the thread, but this is a pilot study with 14 subjects.
Re: Intermittent fasting from dawn to sunset induces anticancer response
#15> Subjects had a significant reduction in body mass index, waist circumference, and improvement in blood pressure Would really like to see this compared to another group with a similar level of calorie restriction but without the intermittent fasting. The question with intermittent fasting is really just "is it better than plain old calorie restriction". Seems like there's some evidence that points to "yes" and some…
My suspicion is that you would see similar improvement with things like waist circumference, BMI, blood pressure, at least initially, but that the difference with intermittent fasting is that it introduces enough of a "fasted state" that the body is able to perform repair and autophagy of senescent cells that would occur much less in a constantly fed state. (something about telomerase, but I probably shouldn't mention that because my memory about that is foggy)
If you increased the amount of fasting, I'd bet good money that people would lose more weight than on a calorie-equivalent diet. Intermittent fasting, in my experience, is helpful in sticking to a diet that is lower in calories because it allows you to eat satisfying meals.
Re: Intermittent fasting from dawn to sunset induces anticancer response
#16Re: Intermittent fasting from dawn to sunset induces anticancer response
#17> Subjects had a significant reduction in body mass index, waist circumference, and improvement in blood pressure Would really like to see this compared to another group with a similar level of calorie restriction but without the intermittent fasting. The question with intermittent fasting is really just "is it better than plain old calorie restriction". Seems like there's some evidence that points to "yes" and some…
My suspicion is that you would see similar improvement with things like waist circumference, BMI, blood pressure, at least initially, but that the difference with intermittent fasting is that it introduces enough of a "fasted state" that the body is able to perform repair and autophagy of senescent cells that would occur much less in a constantly fed state. (something about telomerase, but I probably shouldn't mentio…
From what I understand, autophagy doesn’t start until 18 hours and doesn’t peak until 72 hours.
Re: Intermittent fasting from dawn to sunset induces anticancer response
#18By “no drinking”, do they really mean no drinking plain water? 14 hr stretches are doable but it’s interesting to find your body improving while becoming dehydrated.
The study focused on Muslims observing Ramadan, which does forbid drinking liquids (including water) during the daytime.
Re: Intermittent fasting from dawn to sunset induces anticancer response
#19No control group, and n=14. This study says nothing.
Re: Intermittent fasting from dawn to sunset induces anticancer response
#20By “no drinking”, do they really mean no drinking plain water? 14 hr stretches are doable but it’s interesting to find your body improving while becoming dehydrated.
“Dry fasting” is a thing, but it seems most people recommend against it. Not sure what the added advantage is for avoiding zero calorie water consumption.