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Cognitive deficits in people who have recovered from Covid-19

medrxiv.org

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Re: Cognitive deficits in people who have recovered from Covid-19

#131

Post by mrfusion »

usrusr wrote: post #127
mrfusion wrote: post #90

Earlier quoted context omitted.

I’d be curious to see this compared to people hospitalized on ventilators for other diseases. You’re not in good shape at that point and I’d expect all kinds of problems.

Does it matter though? The answer certainly depends on the context of the question: do we just want to assess the risks more precisely than the dead/alive boolean? No, it doesn't matter. Do we want to increase humanity's knowledge about how the virus affects our bodies? Yes, absolutely, if it's worse than standard damage of respirator episodes we'll want to know the "mechanisms" that we causing that extra damage.

If we’re being asked to give up our way of life, keep children out of school, damage mental health, give up essential freedoms.

Then yes, I’d like to see it compared to existing diseases we’ve been living normally alongside for centuries!

Re: Cognitive deficits in people who have recovered from Covid-19

#134

Post by rfrey »

irq11 wrote: post #122
rfrey wrote: post #84

Earlier quoted context omitted.

Possibly for what HN calls "middlebrow dismissal" - wandering in and dismissing the article with blindingly obvious issues ("probably caused by the sedatives, immobilization" etc) as if professional medical researchers wouldn't have thought of them. They plainly need a clear-eyed HN reader on staff to help them.

A bigger problem on HN these days is the highbrow lowbrow dismissal, wherein people come up with fancy-sounding reasons for rejecting comments, that are actually themselves lazy/incorrect arguments. For example: when the paper itself says that the cognitive declines seen in people who don’t spend time hospitalized are a small fraction of the magnitude of the cognitive declines seen in hospitalized patients (Figures 2…

I was specifically referring to the claim the effects were probably due to sedation, etc. , not the observation that the study was of hospitalized cases.

Re: Cognitive deficits in people who have recovered from Covid-19

#135

Post by snazz »

jansan wrote: post #47
cedex12 wrote: post #20

On the subject of side/long term effects of covid: I've heard, second-hand from doctors/physicians, that the long term effects of covid are not necessarily that bad compared to e.g. the flu. The argument being that: 1. covid has been one of the most studied viruses of this kind, so that you have good chances of stumbling upon lots of size effects, simply due to the sheer size of scrutiny. 2. a bad flu also can yield…

The flu can be nasty. I had a severe case a few years back, and IMO I never fully recovered from it. I consider myself healthy, but I feel that this flu was like getting five years older within two week.

(H1N1)pdm09 was the worst illness I've had, both in duration and severity. Interestingly, that flu virus mostly affected younger people. I'd be interested in reading a thorough comparison of H1N1 and SARS-CoV-2.

Re: Cognitive deficits in people who have recovered from Covid-19

#136

Post by mekoka »

justnotworthit wrote: post #125
dempseye wrote: post #46

Earlier quoted context omitted.

This is a very English way of expressing oneself.

The "not un" has a long history of debate amongst stylists. I believe it's easily overused because it has certain air of erudition about it. However, sometimes "not un" is straightforward and clearer than the alternatives. In this context... well.. science journals have their own English journalese that lives outside general usage.

The double negative has its use beyond language sophistication. It can serve to more specifically mark a neutral stance in a vocabulary that may seem to only offer a dichotomy. e.g. what I have available is I like her and I don't like her, but what I mean to say is I don't dislike her.

Re: Cognitive deficits in people who have recovered from Covid-19

#137

Post by kube-system »

nradov wrote: post #73
redis_mlc wrote: post #4

Earlier quoted context omitted.

> the hospitalised with ventilator sub-group So this affects almost nobody then, and is probably caused by the sedatives, immobilization and ventilator organ damage, aside from corona.

There is some evidence that anesthetics can cause cognitive impairment. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6443620/

I was under the impression, at least as it pertained to the elderly, that GA is commonly known to be a significant risk.

Re: Cognitive deficits in people who have recovered from Covid-19

#138

Post by irq11 »

simonh wrote: post #99
fasteo wrote: post #94

A quick Google search reveals that cognitive deficit seems to be a common consequence in any critically ill patient, not just Covid-19 This study[1] of just one example: Cognitive dysfunction is an important long-term complication of critical illness associated with reduced quality of life, increase in healthcare costs, and institutionalization And the numbers are certainly high: Cognitive impairment was identified i…

Sure as you say critical illness with long term medical effects is known to have this impact. The difference is that, as the abstract points out, substantial cognitive impairment in Covid patients was found even in people who displayed mild symptoms and were never critically ill.

And when you look at the data (Figures 2,3), you’ll see that “substantial” is a subjective term.

For patients who had minor illness and recovered at home, the measured impacts were a fraction of those who spent time in the hospital. In some cases, the data shows a small benefit to having Covid in the minor cases.

Moreover, of the ~84,000 participants, only 361 had a confirmed positive test result.

Re: Cognitive deficits in people who have recovered from Covid-19

#139

Post by [deleted] »

rfrey wrote: post #134
irq11 wrote: post #122

Earlier quoted context omitted.

A bigger problem on HN these days is the highbrow lowbrow dismissal, wherein people come up with fancy-sounding reasons for rejecting comments, that are actually themselves lazy/incorrect arguments. For example: when the paper itself says that the cognitive declines seen in people who don’t spend time hospitalized are a small fraction of the magnitude of the cognitive declines seen in hospitalized patients (Figures 2…

I was specifically referring to the claim the effects were probably due to sedation, etc. , not the observation that the study was of hospitalized cases.

[deleted]

Re: Cognitive deficits in people who have recovered from Covid-19

#140

Post by Raphmedia »

I am glad people are finally looking in that direction. A lot of studies and media attention has been on death rates. This is useful at the start of a pandemic but now we need to look towards the future. Most of us will catch Covid-19 at some point in our lives. What will be the outcome of surviving it?
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