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Cognitive deficits in people who have recovered from Covid-19

medrxiv.org

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Re: Cognitive deficits in people who have recovered from Covid-19

#81

Post by nradov »

isoprophlex wrote: post #3

By no means do I want to detract from the severity of covid infections, but a very important question to answer would be "what's the effect of psychotrauma resulting from illness and hospitalization on cognitive function" I feel that my own cognitive functions have declined as well during the pandemic, due to stress and uncertainty alone. I haven't been infected, mind you.

How can you be sure you haven't been infected? Many cases are asymptomatic, and all available tests sometimes give false negative results.

Re: Cognitive deficits in people who have recovered from Covid-19

#82

Post by treeman79 »

sokoloff wrote: post #57
kasperni wrote: post #2

From the conclusion: "The scale of the observed deficits was not insubstantial; the 0.57 SD global composite score reduction for the hospitalised with ventilator sub-group was equivalent to the average 10-year decline in global performance between the ages of 20 to 70 within this dataset. It was larger than the mean deficit of 512 people who indicated they had previously suffered a stroke (-0.40SDs) and the 1016 who…

It’s equally as surprising to me the suggestion that the average decline in IQ from a stroke would be only 6 points or so.

Varies a lot. I get a lot of minor strokes if I skip blood thinners for a week or so.

At peak I’m a highly effective programmer.

If I’ve had one recently, a “for loop” is a challenging concept.

After a few days to weeks I’ll be back to near normal. Some symptoms last longer.

Highly active Factor 5 Leiden, so I clot like crazy.

Re: Cognitive deficits in people who have recovered from Covid-19

#83

Post by nradov »

pedro-guimaraes wrote: post #7

Much is still to be discovered about the virus, science only knows the effects after less than 1 year. The question is, what could long-term effects of this virus? (let's in 10-20 years)

Most likely the long term effects will be similar to the previous SARS virus. There are thousands of survivors who can be studied.

Re: Cognitive deficits in people who have recovered from Covid-19

#84

Post by rfrey »

ghufran_syed wrote: post #10
redis_mlc wrote: post #4

Earlier quoted context omitted.

> the hospitalised with ventilator sub-group So this affects almost nobody then, and is probably caused by the sedatives, immobilization and ventilator organ damage, aside from corona.

Not sure why you’re getting downvoted - here’s a page about post-intensive care syndrome, on the website of the society for critical care medicine, that’s concordant with what you said: https://www.sccm.org/MyICUCare/THRIVE/Post-intensive-Care-Sy...

Possibly for what HN calls "middlebrow dismissal" - wandering in and dismissing the article with blindingly obvious issues ("probably caused by the sedatives, immobilization" etc) as if professional medical researchers wouldn't have thought of them. They plainly need a clear-eyed HN reader on staff to help them.

Re: Cognitive deficits in people who have recovered from Covid-19

#85

Post by treeman79 »

darkerside wrote: post #78
diu7sieQuee9jai wrote: post #63

Earlier quoted context omitted.

I have been dealing with something that sounds very much like what you describe. It started a few years ago. At the moment it is manageable. I've been in and out of many many doctors' offices. Bloodworks actually indicated a recent (but past) EBV infection, that's why your post rang bells with me. Would you have pointers to how to nail this down? Introductory material or such? I have to say I really feel your descrip…

Sounds similar to Lyme disease as well. I think the body deals with some persistent infections in a similar way, but I've also observed that there is little interest in researching or treating these conditions.

Autoimmune patients often get checked for Lyme, as the symptoms line up well.

Sjogrens, a cousin of lupus, has an insane amount of odd issues associated with it. POTS symptoms, lots of various organ involvement, brain fog, etc.

Re: Cognitive deficits in people who have recovered from Covid-19

#86

Post by diu7sieQuee9jai »

darkerside wrote: post #78
diu7sieQuee9jai wrote: post #63

Earlier quoted context omitted.

I have been dealing with something that sounds very much like what you describe. It started a few years ago. At the moment it is manageable. I've been in and out of many many doctors' offices. Bloodworks actually indicated a recent (but past) EBV infection, that's why your post rang bells with me. Would you have pointers to how to nail this down? Introductory material or such? I have to say I really feel your descrip…

Sounds similar to Lyme disease as well. I think the body deals with some persistent infections in a similar way, but I've also observed that there is little interest in researching or treating these conditions.

Well maybe now we'll get some more interest in it... Hooray! /s

Re: Cognitive deficits in people who have recovered from Covid-19

#87

Post by fogihujy »

neuronic wrote: post #34
fogihujy wrote: post #9

Earlier quoted context omitted.

Well, the fact that someone was uable to breathe on their own also suggests that the virus may have caused a lack of oxygen to the brain. In such circumstances brain damage is quite likely, and then the disease would indeed be the cause. Fortunately, the group of people that end up on ventilators is not really that large, and I can imagine minor brain damage would still be preferable to death in many of those cases.…

People are unable to worry about or comprehend the effects that happen right NOW. I am a staunch believer in post-viral syndrome as I experienced it first hand following an Epstein-Barr infection (mono) but aside from a handful of researchers nobody cares at all. For most physicians, it isn't even within the realm of possibilities when you come to them with random maladies. Boom, now you have anxiety because that's w…

I'm sorry to hear that, but I'm glad you managed to learn to control it somehow.

I personally know two COVID survivors who are experiencing a barrage of various symptoms several months after they were told they were healthy, and new symptoms keep appearing. Both have been in contact with other survivors who've reported the same thing.

Now obviously this is just a single data point (or two depending on how you see it), and I am no medical professional, but I have no doubt what they're experiencing is real and a direct result of COVID. If we assume there are others, even if it is just a small percentage of the people who recover, then we're still going to end up with a shitload of people who will live with a multitude of issues that will make life very difficult. And the worst case is we don't know how much more is to come.

Re: Cognitive deficits in people who have recovered from Covid-19

#88

Post by treeman79 »

noneeeed wrote: post #11
isoprophlex wrote: post #8

Earlier quoted context omitted.

It must be hell to have a bunch of suited figures tell you "we're putting you to sleep, hope to see you on the other side"... and then wake up intubated.

I believe ITU patients often suffer from psychosis while in treatment and PTSD afterwards. Intensive medical intervention really can be incredibly traumatic for many, over and above the trauma of the illness or injury that put you in ITU.

For me the treatments went bad, it was being ignored and dismissed at every stage.

I had a full on embolism in my lung. Multiple doctors and ER missed it. Kept insisting it was anxiety. Only when skin turned completely white did they reluctantly run an x-ray. Oops.

Then I had a reaction to blood thinners. Nurses called me a liar, that no one has a bad reaction. Oh turns out it’s fairly common. Had to let it get to a stroke before they would Change medication.

Repeat at every stage.

Re: Cognitive deficits in people who have recovered from Covid-19

#90

Post by mrfusion »

kasperni wrote: post #2

From the conclusion: "The scale of the observed deficits was not insubstantial; the 0.57 SD global composite score reduction for the hospitalised with ventilator sub-group was equivalent to the average 10-year decline in global performance between the ages of 20 to 70 within this dataset. It was larger than the mean deficit of 512 people who indicated they had previously suffered a stroke (-0.40SDs) and the 1016 who…

I’d be curious to see this compared to people hospitalized on ventilators for other diseases. You’re not in good shape at that point and I’d expect all kinds of problems.
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