Earlier quoted context omitted.
Did you read the text before making this comment? > They found that the new test had 96% sensitivity and 98% specificity.
I'm not sure if thats too good - 98% specificity means that for 1000 infected people, 20 will get away unidentified (false negative). But probably better than other tests, i guess?
India's new paper Covid-19 test
11–20 of 31 posts
Re: India's new paper Covid-19 test
#12I hope this is real and not an Indian Theranos
Re: India's new paper Covid-19 test
#13Interesting, I was led to believe this kind of research could only happen when we let drug companies gouge us for obscene profits.
Re: India's new paper Covid-19 test
#14Earlier quoted context omitted.
Did you read the text before making this comment? > They found that the new test had 96% sensitivity and 98% specificity.
In the UK, only 2.7% of tests are returning positive results. At the end of July, this figure was 0.4%, which puts a floor on the specificity of the existing testing technology at 99.6%. If a test with only 98% specificity were used in the UK, the test would have a positive predictive value (the chance that the positive test represents a true positive result) of about 50%, far worse than existing technology.
Re: India's new paper Covid-19 test
#15Re: India's new paper Covid-19 test
#16Interesting, I was led to believe this kind of research could only happen when we let drug companies gouge us for obscene profits.
Right? Very good job from CSIR Govt. Labs - https://www.csir.res.in/
Re: India's new paper Covid-19 test
#17Earlier quoted context omitted.
Did you read the text before making this comment? > They found that the new test had 96% sensitivity and 98% specificity.
I'm not sure if thats too good - 98% specificity means that for 1000 infected people, 20 will get away unidentified (false negative). But probably better than other tests, i guess?
Re: India's new paper Covid-19 test
#18> Here, we present FnCas9 Editor Linked Uniform Detection Assay (FELUDA)... At the heart of such a detection procedure lies the property of CRISPR proteins to accurately bind to target DNA or RNA, undergo conformational changes leading to cleavage of targets generating a reporter-based signal outcome.
> We then developed a pipeline to adapt FELUDA for an affinity-based fluorescent read-out system, where the amplification step generates biotinylated products which can then be immobilized on magnetic streptavidin beads.
The end-to-end process is similar to PCR and requires specialists to collect samples that are then processed by a lab.
[1] https://www.biorxiv.org/content/10.1101/2020.04.07.028167v2
Re: India's new paper Covid-19 test
#19Earlier quoted context omitted.
Did you read the text before making this comment? > They found that the new test had 96% sensitivity and 98% specificity.
In the UK, only 2.7% of tests are returning positive results. At the end of July, this figure was 0.4%, which puts a floor on the specificity of the existing testing technology at 99.6%. If a test with only 98% specificity were used in the UK, the test would have a positive predictive value (the chance that the positive test represents a true positive result) of about 50%, far worse than existing technology.
It's been above 10%, I think, now for over two weeks.