India's new paper Covid-19 test
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Re: India's new paper Covid-19 test
#2I have already witnessed false-positives with much more elaborate Covid tests so I would be surprised if this test is actually realiable.
Re: India's new paper Covid-19 test
#3I have already witnessed false-positives with much more elaborate Covid tests so I would be surprised if this test is actually realiable.
Did you read the text before making this comment?
> They found that the new test had 96% sensitivity and 98% specificity.
Re: India's new paper Covid-19 test
#4I hope this is real and not an Indian Theranos
Re: India's new paper Covid-19 test
#5 > They found that the new test had 96% sensitivity and 98% specificity. The accuracy of a test is based on these two proportions. A test that's highly sensitive will detect almost everyone who has the disease; and a test that has high-specificity will correctly rule out almost everyone who doesn't have the disease.
> The first ensures not too many false negative results; and the second not too many false positives. India's drug regulator has cleared the test for commercial use.
Seems very promising :)
Re: India's new paper Covid-19 test
#6I have already witnessed false-positives with much more elaborate Covid tests so I would be surprised if this test is actually realiable.
Did you read the text before making this comment? > They found that the new test had 96% sensitivity and 98% specificity.
I'm not sure if thats too good - 98% specificity means that for 1000 infected people, 20 will get away unidentified (false negative). But probably better than other tests, i guess?
Re: India's new paper Covid-19 test
#7According to the article, this is based on "Crispr gene-editing" technologies.
I am no gene-specialist, but apparently it "latches on to a set of letters of a gene carrying the signature of the novel coronavirus, highlights it [with] two blue lines [to] indicate a positive result".
I feel like none of that sounds like it's got much to do with gene editing? CRISPR itself is just a system of DNA, right, but in itself has not got much to do with gene editing?
Re: India's new paper Covid-19 test
#8Interesting, I was led to believe this kind of research could only happen when we let drug companies gouge us for obscene profits.
Re: India's new paper Covid-19 test
#9According to the article, this is based on "Crispr gene-editing" technologies. I am no gene-specialist, but apparently it "latches on to a set of letters of a gene carrying the signature of the novel coronavirus, highlights it [with] two blue lines [to] indicate a positive result". I feel like none of that sounds like it's got much to do with gene editing? CRISPR itself is just a system of DNA, right, but in itself h…
CRISPR is more commonly paired with Cas9. The CRISPR part is the bit that latches onto a specific DNA sequence, and the Cas9 part cuts the DNA at that particular location. So CRISPR is key to gene editing, but can be used in other things like this.
Re: India's new paper Covid-19 test
#10I have already witnessed false-positives with much more elaborate Covid tests so I would be surprised if this test is actually realiable.
Did you read the text before making this comment? > They found that the new test had 96% sensitivity and 98% specificity.
In the UK, only 2.7% of tests are returning positive results. At the end of July, this figure was 0.4%, which puts a floor on the specificity of the existing testing technology at 99.6%.
If a test with only 98% specificity were used in the UK, the test would have a positive predictive value (the chance that the positive test represents a true positive result) of about 50%, far worse than existing technology.