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The First Randomized Controlled Trial on Vitamin D and Covid-19

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Re: The First Randomized Controlled Trial on Vitamin D and Covid-19

#151
post #19

Earlier quoted context omitted.

It’s more likely to kill old and obese people, but there are still plenty of rarer cases of harm to younger fitter people (eg triathletes on oxygen post-infection). It’s not binary.

I'm more concerned about the 30% of Americans that are obese than the 0.1% top athletes, who in rare circumstances are badly affected. Open the gyms to save lives.

You're fantasizing if you think re-opening gyms is going to do jack shit about the obesity rate.

Re: The First Randomized Controlled Trial on Vitamin D and Covid-19

#152
post #27

Earlier quoted context omitted.

This experiment compares vitamin D to no vitamin D, and doesn't say anything about those drugs statistically.

Then why introduce two unknown variables into the study?

Because it's unethical to leave people who are sick with Covid-19 untreated, so they all got what were considered possibly effective treatments at the time.

Re: The First Randomized Controlled Trial on Vitamin D and Covid-19

#153
post #81

Earlier quoted context omitted.

Is there a scientific classification system for evaluating how light vs. dark a person's skin is? I'd like to know how much my relatively darker skin is preventing vit D uptake / creation in the body

There is https://en.wikipedia.org/wiki/Fitzpatrick_scale which I learned about from the apple health app, no idea how widespread it is or how useful it is as a model.

I learned about this from a dermatologist who specializes in skin cancer care. He says it is a very strong indicator for skin damage and cancer risk (sounded stronger than genetic/family history factors), but how it relates to vitamin D deficiency was not really in his domain.

Re: The First Randomized Controlled Trial on Vitamin D and Covid-19

#154

Good on you, Spain. A study like this could never take place in the USA :( Too many powerful people are heavily invested in the belief that there is no treatment for it.

I guess except for these 700 studies, 20 of which involve vitamin D.

https://clinicaltrials.gov/ct2/results?cond=Covid19&term=&cn...

Re: The First Randomized Controlled Trial on Vitamin D and Covid-19

#156
post #104
post #30

Non-white skinned people: sunlight may not be enough to increase your vitamin D. https://www.google.com/search?q=dark+skin+vitamin+d+minutes

Greater than 70% of African Americans are suspected to be Vit D deficient. Definitely worth getting tested if you can [1] especially if you live in the more northern latitudes. Doubly so during winter. [1] with the note that generally insurance is a real PITA with vitamin D testing. The trick usually is to list as a diagnosis code a previous history of low vitamin D. Yes it’s like a catch 22. You need prior testing s…

Using online labs it's super cheap to get it done yourself for less than $50/test. Not worth dealing with insurance BS and your doctor's likely nonsensical ravings about it, just do it and reimburse using your HSA if you have one.

Re: The First Randomized Controlled Trial on Vitamin D and Covid-19

#157

Earlier quoted context omitted.

> My understanding is that it hasn’t been shown for elevators. I think ... Where are you getting this understanding? You are asking for evidence while providing none yourself...

Well the absence of anything is the default, so the burden of proof is on the person making the claim. I had read that somewhere in studying transmissions in NYC where elevators are common. I don’t remember where, it was a while ago.

> Well the absence of anything is the default, so the burden of proof is on the person making the claim.

I'm not sure the concept of "burden of proof" is helpful in a collaborative fact-seeking discussion. It seems more relevant to adversarial debates and trials.

Re: The First Randomized Controlled Trial on Vitamin D and Covid-19

#158
post #30

Non-white skinned people: sunlight may not be enough to increase your vitamin D. https://www.google.com/search?q=dark+skin+vitamin+d+minutes

I'm a pale white person and I'm deficient without supplementation. Anyone reading this that spends lots of hours indoors in front of a computer should probably have their vitamin D level checked. Easy to fix with the right amount of supplement, too much is not good either.

Re: The First Randomized Controlled Trial on Vitamin D and Covid-19

#159
post #109

Earlier quoted context omitted.

"Parallel" generally means that different groups of patients receive different treatments. The opposite is a within-patient study, where all patients get all treatments over time (possibly varying the order to prevent order effects). "Open-label" generally means "not blind at all." Basically, the patient knows what treatment is being administered. "Double-masked" is usually synonymous with "double-blind," because "ma…

>"Double-masked" is usually synonymous with "double-blind," because "masking" sounds less violent than "blinding." This is literally the first time I've heard of "double-blind" being interpreted this way.

[deleted]

Re: The First Randomized Controlled Trial on Vitamin D and Covid-19

#160
post #19

Earlier quoted context omitted.

It’s more likely to kill old and obese people, but there are still plenty of rarer cases of harm to younger fitter people (eg triathletes on oxygen post-infection). It’s not binary.

I'm more concerned about the 30% of Americans that are obese than the 0.1% top athletes, who in rare circumstances are badly affected. Open the gyms to save lives.

1. Weight loss is 90% in the kitchen, not the gym.

2. A gym seems kind-of a high infection risk. Lots of heavy breathing and sweating, wiping of faces, noses, and mouths, sharing of equipment, locker rooms... probably not the ideal place to welcome anyone, let along the (as you say, high-risk) obese amongst us.

Any chance your irritation at closed gyms is more personal, rather than a caring nature looking out for peoples' weight loss regimes?

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