101–110 of 401 posts
Anyone else notice that Calcifediol is the most expensive vitamin-D analogue on the market? What a huge surprise that the study chose that form of vitamin-D specifically.
D3 takes 7 days to be fully metabolised to calcifediol. When Drs measure your D levels, they're actually measuring calcifediol.
Earlier quoted context omitted.
I got one that is still in effect in Michigan- "Gyms are closed" (but bars and casinos are open) A virus that kills old and _obese_ people, and you are shutting down the gym? If anything I hope Coronavirus shifts politicians from business leaders to scientists.
It’s more likely to kill old and obese people, but there are still plenty of rarer cases of harm to younger fitter people (eg triathletes on oxygen post-infection). It’s not binary.
Open the gyms to save lives.
Earlier quoted context omitted.
Anyone can spread it, though. Kids seem to spread it less. Also, the longer this hangs around the more chances it will have to evolve into a form that can harm more demographics. We should want to get rid of Covid-19 as fast as possible. Finally, although many people get asymptomatic infections, this isn't all about death rate. Many many people are suffering brutal damage even if they do survive. This thing targets m…
But bars and casinos are open. If you want to get rid of the virus we need to shut down everything.
Non-white skinned people: sunlight may not be enough to increase your vitamin D. https://www.google.com/search?q=dark+skin+vitamin+d+minutes
[1] with the note that generally insurance is a real PITA with vitamin D testing. The trick usually is to list as a diagnosis code a previous history of low vitamin D. Yes it’s like a catch 22. You need prior testing showing low Vit D to get testing to show low Vit D.
Given the huge prevalence of low vitamin D (70+%) amongst African Americans this is maybe a classic example of a dysfunctional health system. A vitamin D supplement is a dirt cheap public health intervention with potentially big pay offs across such a large segment of the population.
"Don't go outside, you'll get COVID", sounds more and more like horrible advice. Before knowing the virus died in sunlight, I still couldn't fathom why people were avoiding going out to parks and stuff. It was totally non sequitor.
I got one that is still in effect in Michigan- "Gyms are closed" (but bars and casinos are open) A virus that kills old and _obese_ people, and you are shutting down the gym? If anything I hope Coronavirus shifts politicians from business leaders to scientists.
Earlier quoted context omitted.
Considering that the risk of transmission seems to depend on how long you are inhaling shared air from an infected person, and their viral load, I don't think it makes sense to worry about intermittently going through someone else's exhaust plume. I use a mask outside if I'm on a narrow sidewalk, but otherwise, I don't think there's much point. My favourite thing is the people who wear a mask over the mouth, but not…
> Considering that the risk of transmission seems to depend on how long you are inhaling shared air from an infected person, and their viral load You have a lot of faith in your immune system. Absent more data, it's just that, faith.
We have simply not seen the increases and flare-ups we would expect if what you're asserting is true. What worries me is October-November. This is for Toronto, Canada.
The beaches and parks are fully of people socially distancing-ish. The streets are full of a mix of people social distancing and not. Maybe half are wearing masks.
Get outside and take care of your physical and mental health! Winter is coming.
EDIT> I'm a physics and biology student. I am not completely unaware of the science.
Earlier quoted context omitted.
Don't really know why you haven't found the most obvious explanation for why you've gotten fewer colds.
Vitamin D has a direct effect on colds. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5949172/
I swear, it's like people don't understand why we measure R_t. propagation is sigmoidal phenomenon. A reduction in transmission by 10% can easily lead to a reduction in prevalence by nearly 100%.
Anyone else notice that Calcifediol is the most expensive vitamin-D analogue on the market? What a huge surprise that the study chose that form of vitamin-D specifically.
I assume that the researchers picked it (1) to increase the chances of seeing a significant effect, if there is one, and (2) because if hours are at stake in saving a person's life, the fastest boost may be needed.
> parallel pilot randomized open label, double-masked clinical trial. Dumb questions: What is a parallel pilot | what is open label? And Is double-masked the same as double-blind?
"Parallel" generally means that different groups of patients receive different treatments. The opposite is a within-patient study, where all patients get all treatments over time (possibly varying the order to prevent order effects). "Open-label" generally means "not blind at all." Basically, the patient knows what treatment is being administered. "Double-masked" is usually synonymous with "double-blind," because "ma…
This is literally the first time I've heard of "double-blind" being interpreted this way.
Fascinating how hydroxychloroquine is routinely used and considered standard of care in most countries where the drug has not been politicized.