Earlier quoted context omitted.
I've had Uber drivers pick me up and refuse to go to the part of the city I wanted to go to... complete pain in the ass (and also racist in this specific case). Uber offered me $5 for my trouble each time, which is... very Uber.
If the part of the city is unsafe (as some parts of some major cities are frequently nowdays) to the point the driver risks being assaulted by a mob, dragged out and beaten or shot, and their vehicle destroyed - I see no reason why they shouldn't be able to refuse such ride. No ride worth your life, and unless you're paying 1000x the Uber rates, no ride is worth your car ruined.
Pretending this isn't a reality or that it doesn't have an impact on someone driving for a living is pretty asinine.