Brain-Gut Circuit Lets Microbiota Directly Affect the Sympathetic Nervous System • Hacker News Board

Re: Brain-Gut Circuit Lets Microbiota Directly Affect the Sympathetic Nervous System

#31

Post by elbear » Mon, Aug 03, 2020, 5:26 AM UTC

pfundstein wrote: post #9

andai wrote: post #7

Earlier quoted context omitted.

I tried eating just steaks for a few days, and it absolutely blew my mind (1) how stable my energy was, how energetic I felt (2) how I wouldn't get hungry at all for 8-10 hours. Normally I start thinking about food an hour or two after eating!

The key to a good diet is balance. Too much red meat has equally severe health implications, leading to a higher risk for heart disease, cancer, diabetes, and premature death.[1][2] [1] https://www.health.harvard.edu/staying-healthy/whats-the-bee... [2] https://pubmed.ncbi.nlm.nih.gov/26780279/

Here's a different perspective on it: https://examine.com/nutrition/does-red-meat-cause-cancer/

Re: Brain-Gut Circuit Lets Microbiota Directly Affect the Sympathetic Nervous System

#32

Post by ak39 » Mon, Aug 03, 2020, 6:12 AM UTC

pfundstein wrote: post #23

chrisco255 wrote: post #13

Earlier quoted context omitted.

Mankind evolved to eat red meat. We developed fire for it. We invented spears and bow hunting for it. It's one of the healthiest foods you can consume, has been part of the human diet for over 2 million years... and besides the noted protein, it contains B12, Zinc, Selenium, Iron, Niacin, B6, Phosphorous and many other valuable nutrients. You can live exclusively off a diet of just red meat and live a long, healthy l…

Mankind rarely lived beyond 25 until very recently so the long-term effects of high red meat consumption have never been part of the evolutionary equation. There have been numerous long term studies that have found strong links between diseases, esp. heart disease, diabetes, cancer. These diseases take years to manifest normally thus wouldn't have existed then. Edit: s/didn't live/rarely lived/

Source please.

Re: Brain-Gut Circuit Lets Microbiota Directly Affect the Sympathetic Nervous System

#33

Post by fiblye » Mon, Aug 03, 2020, 6:12 AM UTC

wincy wrote: post #14

amelius wrote: post #12

Earlier quoted context omitted.

It's a pity there aren't many foods with a sugar level that tastes well to people who aren't acclimated to eating sugary things. The food industry has decided it's either no sugar or lots of sugar, so it seems.

Try Korean/Asian markets. I worked with a few Koreans and they thought treats sold in the USA were way too sweet. They had sweet bean curd things that tasted great when I was doing Keto and while it wouldn’t be good to eat every day they were a nice snack sometimes.

It's surprising to look at the nutrition labels for anko/sweet red bean paste. It seems like it'd be a healthy alternative, but it's basically concentrated sugar cake.

I live in Japan. I've eaten plenty of it. It's the health equivalent of cake frosting in Asia.

Re: Brain-Gut Circuit Lets Microbiota Directly Affect the Sympathetic Nervous System

#34

Post by [deleted] » Mon, Aug 03, 2020, 6:27 AM UTC

nikkwong wrote: post #21

Vaslo wrote: post #15

The brain gut connection is incredible. For years I suffered with terrible IBS where I would almost always get nauseous after eating and would often need to immediately go to the bathroom. I also had a very difficult time gaining weight. I tried all kinds of drugs - prescriptions to treat nausea, malabsorption, even gastroparesis (slow emptying of the stomach). Nothing worked and a few of the prescriptions were nerve…

Would you mind disclosing who the doctor was? I have been dealing with this for years and it's been wreaking havoc on my personal and professional lives. Doctors in my area are not familiar with my condition and don't have a solution. I'm especially tired of the malabsorption, dietary restrictions, sleeping issues, inability to gain weight, edema.. a whole laundry list. Would love to hear your doctor's opinion. I am…

[deleted]

Re: Brain-Gut Circuit Lets Microbiota Directly Affect the Sympathetic Nervous System

#35

Post by ordu » Mon, Aug 03, 2020, 7:48 AM UTC

chrisco255 wrote: post #13

pfundstein wrote: post #9

Earlier quoted context omitted.

The key to a good diet is balance. Too much red meat has equally severe health implications, leading to a higher risk for heart disease, cancer, diabetes, and premature death.[1][2] [1] https://www.health.harvard.edu/staying-healthy/whats-the-bee... [2] https://pubmed.ncbi.nlm.nih.gov/26780279/

Mankind evolved to eat red meat. We developed fire for it. We invented spears and bow hunting for it. It's one of the healthiest foods you can consume, has been part of the human diet for over 2 million years... and besides the noted protein, it contains B12, Zinc, Selenium, Iron, Niacin, B6, Phosphorous and many other valuable nutrients. You can live exclusively off a diet of just red meat and live a long, healthy l…

> Mankind evolved to eat red meat. We developed fire for it.

I read somewhere that in some sense minkind devolved to eat red meat. Some gene was damaged, which helped humans to do a marathon activity to track red meat running away (IIRC something to do with an ability of blood to carry oxygen), but humans lost a key enzyme to process fatty acids from red meat. So mankind got more proteins but started to die from heart desease. Probably it was no so bad then because an average lifespan was too short to develop severe symptoms.

Sorry, cannot find a link.

Re: Brain-Gut Circuit Lets Microbiota Directly Affect the Sympathetic Nervous System

#36

Post by muraiki » Mon, Aug 03, 2020, 8:01 AM UTC

jryan49 wrote: post #19

Vaslo wrote: post #15

The brain gut connection is incredible. For years I suffered with terrible IBS where I would almost always get nauseous after eating and would often need to immediately go to the bathroom. I also had a very difficult time gaining weight. I tried all kinds of drugs - prescriptions to treat nausea, malabsorption, even gastroparesis (slow emptying of the stomach). Nothing worked and a few of the prescriptions were nerve…

I have a similar anecdote. Starting an ssri (luvox) cured my ibs.

I was prescribed Amitriptyline for post concussion syndrome, and noticed that my IBS basically stopped. I forget the dosage and how long I took it—-perhaps six months to a year—-but after I discontinued it, my IBS didn’t return. Although maybe the concussion knocked things around in a way that fixed it. :)

Re: Brain-Gut Circuit Lets Microbiota Directly Affect the Sympathetic Nervous System

#37

Post by starfallg » Mon, Aug 03, 2020, 8:13 AM UTC

nikkwong wrote: post #21

Vaslo wrote: post #15

The brain gut connection is incredible. For years I suffered with terrible IBS where I would almost always get nauseous after eating and would often need to immediately go to the bathroom. I also had a very difficult time gaining weight. I tried all kinds of drugs - prescriptions to treat nausea, malabsorption, even gastroparesis (slow emptying of the stomach). Nothing worked and a few of the prescriptions were nerve…

Would you mind disclosing who the doctor was? I have been dealing with this for years and it's been wreaking havoc on my personal and professional lives. Doctors in my area are not familiar with my condition and don't have a solution. I'm especially tired of the malabsorption, dietary restrictions, sleeping issues, inability to gain weight, edema.. a whole laundry list. Would love to hear your doctor's opinion. I am…

I had similar experiences, but with amitriptyline at the lowest dose of 10mg taken every night. At 25mg I was too drowsy. It drastically improved all of my chronic problems almost immediately - gut problems (IBS-D), inability to sleep more than a few hours, and issues with peripheral nerves.

Amitriptyline has a slight sedative effect compared to nortriptyline, which is good if you suffer problems with sleep, but has slightly more side effects.

I'm in the UK, and a GP at my previous clinic prescribed me this. Your doctor should be able to also, there shouldn't be a need to see a specialist.

Re: Brain-Gut Circuit Lets Microbiota Directly Affect the Sympathetic Nervous System

#38

Post by FreeFull » Mon, Aug 03, 2020, 8:39 AM UTC

Vaslo wrote: post #15

The brain gut connection is incredible. For years I suffered with terrible IBS where I would almost always get nauseous after eating and would often need to immediately go to the bathroom. I also had a very difficult time gaining weight. I tried all kinds of drugs - prescriptions to treat nausea, malabsorption, even gastroparesis (slow emptying of the stomach). Nothing worked and a few of the prescriptions were nerve…

The gut has its own nervous system: https://en.wikipedia.org/wiki/Enteric_nervous_system . Usually the effects of antidepressants on the gut are considered an unwanted side-effect, but in your case it was the intended effect.

Re: Brain-Gut Circuit Lets Microbiota Directly Affect the Sympathetic Nervous System

#39

Post by agumonkey » Mon, Aug 03, 2020, 8:53 AM UTC

Vaslo wrote: post #15

The brain gut connection is incredible. For years I suffered with terrible IBS where I would almost always get nauseous after eating and would often need to immediately go to the bathroom. I also had a very difficult time gaining weight. I tried all kinds of drugs - prescriptions to treat nausea, malabsorption, even gastroparesis (slow emptying of the stomach). Nothing worked and a few of the prescriptions were nerve…

I don't know how doctors would feel but maybe it's time to have a system to query more than one doctor for patient's ailments. Instead of waiting to run into the occasional pro that actually knows your issue and fix it with a switch.

No need for moonshot AI just an large aggregative system that let's curious doctor that are very capable in a subfield scan open issues for diagnosis.

Re: Brain-Gut Circuit Lets Microbiota Directly Affect the Sympathetic Nervous System

#40

Post by agumonkey » Mon, Aug 03, 2020, 9:06 AM UTC

msandford wrote: post #5

BLKNSLVR wrote: post #4

Earlier quoted context omitted.

18 months off sugar and I still have to consciously view dessert items as akin to poison to quell the desire to eat all of them.

My dad's dad had a sweet tooth, my dad has one, and I do too. About a month ago I resolved to eating at least 100g of protein per day (1.2g/kg) to see if that wouldn't help me with some recovery and healing. It was a real chore to eat that much. I would eat three eggs and black beans for breakfast to get ~30g, then shoot for 30-40g for lunch and another 30-40g for dinner. I was eating a lot of cottage cheese to make…

I don't eat proteins but I do fill my stomach with raw veggies. The desire for sweets is really boredom turned into nutrition. When you're full you barely want anything anymore. Also the less sweet (and processed food which are allegedly heavy on fat and various sugar) you start to feel subtle taste better. Carrots are sweet.. I feel like eating candy, but it's not strong. Even lettuce has some delicacy to it.

There's an irony to our nutrition, we pay for industrial _ _ _ _ that is bad for us then pay for solutions. Just eat basic stuff and go do something fun.