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Glucosamine Supplementation Reduces All-Cause Mortality: Study

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41–50 of 153 posts

Re: Glucosamine Supplementation Reduces All-Cause Mortality: Study

#41
post #33

To people who put too much stock in these "studies", consider this: as of July 2020 we _still_ have no conclusive answer if _eggs_ are good for you or not. What makes you believe this is any different?

We're still waiting for them to figure out salt.

Re: Glucosamine Supplementation Reduces All-Cause Mortality: Study

#42

are there dietary sources of glucosamine?

Yes - cartilage. If you eat chicken or something like that, eat the cartilage. You can do this on pre-cooked chickens you get from Sam's Club / Costco. If you eat chicken breasts only (which a lot of health-conscious people do), you don't get this benefit. I talked to Dr.Yang Jwing Ming (one of the few Kung Fu practioners with a Western phd and he said eating cartilage is one of the best ways to help reduce the risk…

I read research that to reap benefits of these sources ( collagen, etc) your stomach acid needs to be strong enough to break it down- old people have weaker stomach acid so they get wrinkles easier- Supplement apple cider vinegar, lemon juice etc or other fermented foods raises stomach acid strength and raises blood Alkalinity, or so I heard

Re: Glucosamine Supplementation Reduces All-Cause Mortality: Study

#43

are there dietary sources of glucosamine?

there's no reason to believe macromolecules like glucosamine benefit the body any more than regular, nutritious food. ingested nutrition generally gets broken down into amino acids and the like in the digestive system before it gets distributed to the rest of the body to be reconsistuted into cells and tissue. cartilage in particular is scaffolding and generally must be constructed by other cells from very basic mole…

You raise a good point, but wouldnt taking glucosamine and chondroitin load you up (hopefully) on the base components required to then again make glucosamine and chondroitin locally in one's body?

Re: Glucosamine Supplementation Reduces All-Cause Mortality: Study

#44

are there dietary sources of glucosamine?

It is important to remember the study only saw a correlation between the dietary supplement and mortality. Glucosamine Sulfate is from what I understand the most common form in the supplements on the shelf. Our bodies produce glucosamine naturally. > Specifically in humans, glucosamine-6-phosphate is synthesized from fructose 6-phosphate and glutamine by glutamine—fructose-6-phosphate transaminase as the first step o…

Don't worry. By the time [insert popular news outlet] finds out about this, it'll be a cure all.

Re: Glucosamine Supplementation Reduces All-Cause Mortality: Study

#45
https://examine.com/supplements/glucosamine/

Always used this site when trying to find unbiased information, and also not be to hyped about a single study. However now the effect matrix is hidden behind a paywall.

When talking about joint health: As a young and very active person my biggest problem is overtraining injuries. Wish I knew how to be able to train as much as I would like to, with just a simple supplement or so...

Re: Glucosamine Supplementation Reduces All-Cause Mortality: Study

#46
post #24

I've been supplementing glucosamine along with a large amount of other things for awhile now. I'm not too bullish on it in humans, but it doesn't seem like it hurts, and is definitely cheap: https://nearcyan.com/supplements My latest favorites that I'm a bit more hopeful for are glycine, spermadine, and rapamycin.

How are you getting rapamycin?

I'm interested in it's benefits for autoimmune diseases but it seems quite expensive (in the US).

Re: Glucosamine Supplementation Reduces All-Cause Mortality: Study

#47
post #30

Earlier quoted context omitted.

> Edit: Yea, reading the study, I don't see anything about controlling for fitness level. They specifically control for the following lifestyle factors: "smoking status, alcohol consumption, physical activity, body mass index (BMI) and vegetable and fruit consumption." (Ctrl+f for "covariates") In the conclusion, they acknowledge: "Although we had carefully adjusted for potential confounding lifestyle-related factors…

But if someone "works out heavily and supplements," that should show up in self reported physical activity, and indirectly in BMI. Well, not to nitpick, but people with high muscle mass can easily end up with an "obese" BMI even if they have very low body fat. And it also doesn't take very many hours of working out per week to get jacked if you're doing heavy weightlifting and supplementing. No idea if such people ar…

Sure, some (not a huge fraction, I'm guessing single digit percentage) of very physically active people are poorly modeled by BMI but it shouldn't matter if they are explictly handling these covariates.

It's more an issue if there is something they haven't accounted for, as they point out.

Re: Glucosamine Supplementation Reduces All-Cause Mortality: Study

#48
I've given glucosamine to my dogs for years, and I can clearly notice a difference in their joint health and how stiff and sore they are after long runs ('long-run': 15-25 miles, measured on GPS collars). When I run out of glucosamine, or just drop off of giving it to them for whatever reason, I see them fall back pretty quickly. And when I restart them on it, I notice a response in a few days.

I also give give them fish oil pills, but I've never been able to notice a difference.

Re: Glucosamine Supplementation Reduces All-Cause Mortality: Study

#50
post #38
post #32

Earlier quoted context omitted.

Do you take each Vitamin individually, or do you take a multivitamin? Do you make an effort to get large doses of these things from food first?

Individually. Sometimes a few things are combined when a good option is available, but generally multivitamins don't give me what I want in the doses that I want. Since I tested all of my blood metrics beforehand, it's unlikely the market would have a 'perfect' vitamin for me. Especially since most of what I like to take isn't technically a vitamin. My diet is currently pretty un-optimized, so although I would prefer…

Id be curious what it would look like if you tested your blood now, stopped taking them all, and radically modified your died, what kind of results you would get in a couple weeks.

Daily intake of, tomato juice, kefir, sardines, salmon, spinach, sunflower seeds, pumpkin seeds, pistachio, eggs. You could probably get a whole days worth of food into a snack, a salad, and a soup.

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