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Glucosamine Supplementation Reduces All-Cause Mortality: Study

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Re: Glucosamine Supplementation Reduces All-Cause Mortality: Study

#31

Post by pruneridge »

throw1234651234 wrote: post #6
bigpumpkin wrote: post #5

are there dietary sources of glucosamine?

Yes - cartilage. If you eat chicken or something like that, eat the cartilage. You can do this on pre-cooked chickens you get from Sam's Club / Costco. If you eat chicken breasts only (which a lot of health-conscious people do), you don't get this benefit. I talked to Dr.Yang Jwing Ming (one of the few Kung Fu practioners with a Western phd and he said eating cartilage is one of the best ways to help reduce the risk…

I really hope at some point in our lifetimes, the deleterious effects of animal protein are pervasively understood by educated Americans to the point where consuming animal parts for their anti-inflammatory benefits would be an oxymoron on par with smoking to prevent cancer. An overwhelming body of scientific evidence suggests that humans are omnivores and not carnivores and the human body evolved to process animal protein on an occasional basis(like alcohol) and not because it’s good for us on a daily basis.

Re: Glucosamine Supplementation Reduces All-Cause Mortality: Study

#32

Post by basch »

ve55 wrote: post #24

I've been supplementing glucosamine along with a large amount of other things for awhile now. I'm not too bullish on it in humans, but it doesn't seem like it hurts, and is definitely cheap: https://nearcyan.com/supplements My latest favorites that I'm a bit more hopeful for are glycine, spermadine, and rapamycin.

Do you take each Vitamin individually, or do you take a multivitamin?

Do you make an effort to get large doses of these things from food first?

Re: Glucosamine Supplementation Reduces All-Cause Mortality: Study

#34

Post by richdougherty »

bernie_simon wrote: post #13
CyberDildonics wrote: post #8

This title is not the title of the study. "Associations of regular glucosamine use with all-cause and cause-specific mortality: a large prospective cohort study" This does not mean it reduces all cause mortality. This is correlation, not causation. To take this further, there might be no limit to what you could correlate to some degree with all-cause mortality, especially since it might be heavily correlated to finan…

"The UK Biobank used a baseline touch screen questionnaire to assess several potential confounders: sociodemographic characteristics (age, sex, ethnicity, Townsend Deprivation Index, education and average total annual household income), lifestyle behaviours (smoking status, alcohol consumption, physical activity, body mass index (BMI) and vegetable and fruit consumption), health conditions (CVD (myocardial infarction…

Still, the authors accept correlation as a potential objection, despite doing their best to control for it. I suppose they need a randomised controlled study or something to be more certain.

"Third, regular glucosamine use may be a marker for a healthy lifestyle, but it is hard to distinguish the confounding effects of a healthy lifestyle from the impact of regular supplementations in an observational study. Although we had carefully adjusted for potential confounding lifestyle-related factors in our analyses, we could not exclude the possibility that the results were confounded by unmeasured lifestyle-related factors. In general, with the current observational study design the possibility of residual confounding due to imprecise measurements or unknown factors cannot be excluded for all findings in our study, despite our careful adjustment of all measured confounders."

Re: Glucosamine Supplementation Reduces All-Cause Mortality: Study

#36

Post by hombre_fatal »

lottin wrote: post #18
throw1234651234 wrote: post #6

Earlier quoted context omitted.

Yes - cartilage. If you eat chicken or something like that, eat the cartilage. You can do this on pre-cooked chickens you get from Sam's Club / Costco. If you eat chicken breasts only (which a lot of health-conscious people do), you don't get this benefit. I talked to Dr.Yang Jwing Ming (one of the few Kung Fu practioners with a Western phd and he said eating cartilage is one of the best ways to help reduce the risk…

Westerners have eaten pig ears for centuries.

I would be surprised if I've met anyone in the US who has eaten pig ear nor the chicken feet you see next to them in the hispanic market. And just about everyone would react to the ick factor.

I don't think it's as common as you think: https://en.wikipedia.org/wiki/Pig%27s_ear_(food).

Re: Glucosamine Supplementation Reduces All-Cause Mortality: Study

#38

Post by ve55 »

basch wrote: post #32
ve55 wrote: post #24

I've been supplementing glucosamine along with a large amount of other things for awhile now. I'm not too bullish on it in humans, but it doesn't seem like it hurts, and is definitely cheap: https://nearcyan.com/supplements My latest favorites that I'm a bit more hopeful for are glycine, spermadine, and rapamycin.

Do you take each Vitamin individually, or do you take a multivitamin? Do you make an effort to get large doses of these things from food first?

Individually. Sometimes a few things are combined when a good option is available, but generally multivitamins don't give me what I want in the doses that I want.

Since I tested all of my blood metrics beforehand, it's unlikely the market would have a 'perfect' vitamin for me. Especially since most of what I like to take isn't technically a vitamin.

My diet is currently pretty un-optimized, so although I would prefer to consume a lot of things via diet, it's not guaranteed at all. But the extra bio-availability and such is likely nice

Re: Glucosamine Supplementation Reduces All-Cause Mortality: Study

#39

Post by CyberDildonics »

bernie_simon wrote: post #13
CyberDildonics wrote: post #8

This title is not the title of the study. "Associations of regular glucosamine use with all-cause and cause-specific mortality: a large prospective cohort study" This does not mean it reduces all cause mortality. This is correlation, not causation. To take this further, there might be no limit to what you could correlate to some degree with all-cause mortality, especially since it might be heavily correlated to finan…

"The UK Biobank used a baseline touch screen questionnaire to assess several potential confounders: sociodemographic characteristics (age, sex, ethnicity, Townsend Deprivation Index, education and average total annual household income), lifestyle behaviours (smoking status, alcohol consumption, physical activity, body mass index (BMI) and vegetable and fruit consumption), health conditions (CVD (myocardial infarction…

They tried to control for as much as they could, but that doesn't make the title accurate. The authors don't claim what the title says.

Re: Glucosamine Supplementation Reduces All-Cause Mortality: Study

#40

Post by ghastmaster »

bigpumpkin wrote: post #5

are there dietary sources of glucosamine?

It is important to remember the study only saw a correlation between the dietary supplement and mortality. Glucosamine Sulfate is from what I understand the most common form in the supplements on the shelf. Our bodies produce glucosamine naturally.

> Specifically in humans, glucosamine-6-phosphate is synthesized from fructose 6-phosphate and glutamine by glutamine—fructose-6-phosphate transaminase as the first step of the hexosamine biosynthesis pathway -wikipedia

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