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Low carb diet leads to “clinical remission” in 3 cases of type 1 diabetes

diabetes.co.uk

71–80 of 148 posts

Re: Low carb diet leads to “clinical remission” in 3 cases of type 1 diabetes

#71
post #5

Balance in diet seems to be the one principal that will never go away. I'm suspicious of any diet that eats too much of one thing, especially if it claims the other things are harmful.

The term "balance" is meaningless unless we know what kind of values are ascribed to "too much" which is exactly what we are trying to sort out. No one talks about eating a "balanced" amount of high fructose corn syrup, in terms of nutritional benefit.

I agree, it depends on the definition of the spectrum or range of values that would then provide a definition of balance. Maybe the food groups could be the level at which this is defined, so too much or too little of one food group is probably not good. A good example is the meat-only diet that became a recent fad. People can claim all kinds of benefits there but in the long run it's just not balanced, and we're not built like apex predators in nature.

Re: Low carb diet leads to “clinical remission” in 3 cases of type 1 diabetes

#72

I'm a type 1 diabetic and find these articles and studies frustrating. Or at least the way people interpret them. > Two weeks after adopting the low carb approach insulin was no longer needed. After 18 months insulin therapy was once again required at low doses of around 16 units per day. HbA1c remained very well controlled on the LCHF diet with insulin. So during the honeymoon period, he was able to live without ins…

Here is the actual study [1]. This is n=3, so we are talking about highly anecdotal data. Nonetheless, I think this statement is misplaced:

> Low carb diets can help type 1 diabetics, but it's not a cure

Likely, as in most cases, the real picture is much more complex. It could be the case that LCHF diets can cure some percentage of individuals, can help some percentage and can be detrimental perhaps even fatal to some percentage. All of these could easily be simultaneously true.

Indeed, in case 1 it seems to have possibly "cured" the patient, though he could have also easily been a false positive or there could have been any number of other confounding factors. I quote from the study:

"He was able to stop insulin completely 15 days later (after diagnosis), and has not used insulin since March 2015." and "In the 4 years since his diagnosis, he has had no diabetes-related complications".

Here is patient #2's summary:

"He stopped insulin therapy at the beginning of the diet and has not used insulin since, except for one infectious episode." and " At 1 year after the diagnosis, he had no diabetes-related complications".

Also of note, both of these patients had started exercising 1-2 h a week, and 2 and 2-3 times a week respectively, before the diagnosis.

1. https://www.sciencedirect.com/science/article/abs/pii/S12623...

Re: Low carb diet leads to “clinical remission” in 3 cases of type 1 diabetes

#73
post #26

From last year (July 2019), and no follow-up. As someone who has to deal with T1D every day and carefully monitors news about research, I guarantee you no endocrinologist is counseling their patients to try this. Cutting carbs can lead to less need for insulin, but it's not a cure for T1D.

Yep. When I've consciously gone low carb, my insulin requirements have gone down, and my blood sugar was much more manageable. But if I had stopped taking insulin entirely I would have died or ended up in the hospital with DKA.

With this regimen, you would simply do as your blood sugar numbers direct. It sounds like these patients were measuring and found their glucose to be too low if they took any insulin. In that case, it is safe to stop if coordinated with a doctor. There shouldn’t be any point where a decision is made to drop insulin permanently while your reads are high.

Even if stopping insulin prematurely, low carb would mean low risk of DKA due to slowly rising glucose, giving plenty of time to react. Dropping long-acting insulin would be harder to revert, but frequent small doses of short-acting would be an effective stop-gap.

A good general principle for us diabetics is to encourage everyone to safely explore the control they have over their particular flavor of this disease, and respect whatever those limits turn out to be. :)

Re: Low carb diet leads to “clinical remission” in 3 cases of type 1 diabetes

#74
post #67

Earlier quoted context omitted.

so. this is so general that it’s not helpful. what ranges are we talking about? also, when people talk about cholesterol they usually don’t mean cholesterol they mean lipi-proteins that carry the cholesterol through the blood (cholesterol needs this as it’s hydrophobic). LDL from those lipo-proteins is definitely correlated with heart disease. Here, read about it in more detail than you probably need to know: https:/…

>this is so general that it’s not helpful I think digging into the minutiae of specific numbers is silly, when the better frame is to construct the right diet the comports w/ human evolution and lifestyle, energy, activity and go from there. Generally low carb (particularly avoiding high glycemic index carb, and sugars) preferring lower starch vegetables, while prioritizing animal fats, meat, fish. Keto / keto carniv…

[deleted]

Re: Low carb diet leads to “clinical remission” in 3 cases of type 1 diabetes

#75

Earlier quoted context omitted.

Hugely reducing insulin dosing is still probably valuable, especially for Americans since it's so expensive.

It's expensive but not as bad as you'd think. I didn't have insurance for half a year, and I just called the manufacturer and got a huge discount ($200/bottle -> $35/bottle). One bottle lasts a month or so. This was only due to not having insurance and wasn't need-based - I had earned FAANG income earlier that year and the year before.

Both those prices seem excessive.

Re: Low carb diet leads to “clinical remission” in 3 cases of type 1 diabetes

#76
post #49

Earlier quoted context omitted.

He never mentioned it being a cure to T1D..

The response is to an article about low carb diets sending diabetes patients into "remission". It's hard not to make the connection.

Well.. I don't actually think the article claims a 'cure' either.

If I get cancer, have treatment for it and am now in remission, who would think these doctors 'cured' cancer? Everyone would understand _my specific instance_ of cancer is reduced to being not a concern anymore.

Being in remission just means a greatly reduced or almost inexistent dependency on insulin.

I'm not saying the conclusions of the article are correct either (low sample size, short period of time), but it's a far cry from claiming 'LCHF cures T1D'

Re: Low carb diet leads to “clinical remission” in 3 cases of type 1 diabetes

#77
post #62

Earlier quoted context omitted.

This is not getting through... If you are consuming your 2000 calories diet, and it is coming from plants, you are still ingesting 2000 calories worth of carbs..... 1 kg of feathers, and 1 kg of iron, weight the same.... The feathers will be large and take more volume, while the iron will be small and more dense. Same with foods.... if your plant based diet you are consuming 2000 worth of bio-available calories, then…

Tofu, seitan, tempeh made without rice, etc are plant-based, high protein and low carb. Various fungi fall into the same category, although they aren't plants. Make a dish with vegetable oil and you'll have a high fat and protein meal with minimal carbs that is plant-based.

Makes sense, so are avocados, olives ect... (mostly fat), but you are essentially eliminating 90% of plants out there...

When you say Plant based diet, people assume lettuce, beans, tomatos, carrots, olives, broccoli, etc.. etc...

Re: Low carb diet leads to “clinical remission” in 3 cases of type 1 diabetes

#78
post #67

Earlier quoted context omitted.

so. this is so general that it’s not helpful. what ranges are we talking about? also, when people talk about cholesterol they usually don’t mean cholesterol they mean lipi-proteins that carry the cholesterol through the blood (cholesterol needs this as it’s hydrophobic). LDL from those lipo-proteins is definitely correlated with heart disease. Here, read about it in more detail than you probably need to know: https:/…

>this is so general that it’s not helpful I think digging into the minutiae of specific numbers is silly, when the better frame is to construct the right diet the comports w/ human evolution and lifestyle, energy, activity and go from there. Generally low carb (particularly avoiding high glycemic index carb, and sugars) preferring lower starch vegetables, while prioritizing animal fats, meat, fish. Keto / keto carniv…

i don’t like this line of thinking. digging in can help you tailor your diet and lifestyle on the genetics you have. also, decades of medical research cannot just be swept away based on a gut feeling. do know everything? no. do we have some good indicators? definitely.

Re: Low carb diet leads to “clinical remission” in 3 cases of type 1 diabetes

#79
post #77

Earlier quoted context omitted.

Tofu, seitan, tempeh made without rice, etc are plant-based, high protein and low carb. Various fungi fall into the same category, although they aren't plants. Make a dish with vegetable oil and you'll have a high fat and protein meal with minimal carbs that is plant-based.

Makes sense, so are avocados, olives ect... (mostly fat), but you are essentially eliminating 90% of plants out there... When you say Plant based diet, people assume lettuce, beans, tomatos, carrots, olives, broccoli, etc.. etc...

You eat those on the side, particularly lettuce, spinach, broccoli etc in as large of quantities as you'd like because they're low in carbs.

Re: Low carb diet leads to “clinical remission” in 3 cases of type 1 diabetes

#80

Earlier quoted context omitted.

The Ketoers say this isn't a problem. That cholestorol is misunderstood, and high values are only bad if you eat high carbs. If your low carb then the high value is actually normal and healthy. But YMMV

It's anecdotal evidence, but I know of a fairly young person who is now prescribed statins after overeating animal fat for their keto diet.

Statins are poison.
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