Earlier quoted context omitted.
I still think its fair to say we use the equal temperment system. It is a widely accepted standard. You're right, fret pressure alone can absolutely raise the pitch 5/10 cents, my Gibson SG has some deep frets and can do double that. I am surprised with all of the technology and VSTs we have now no one really uses self adjusting Just intonation or challenges A 440. Musical / mathematical / technical ability are a rar…
Check Jacob Collier if you haven't already. He is really pushing it, he has a song where he changes the temperament during the song (sorry if this imprecise/wrong). He is kinda like a musical prodigy. Not my cup of tea but I do recognize he is very refreshing.
https://www.ethanhein.com/wp/2019/jacob-colliers-four-magica...
That's just the beginning. He posts long breakdowns of his tracks on YouTube explaining everything he does in detail. He's not only a musical virtuoso, but he's incredibly adept at recording and Apple's Logic/tech in general, so he's able to blend those skills seamlessly.
With Jacob and others getting people interested in tunings and unusual harmony, there are now lots of people on YouTube creating music that exploits shifting tunings or alternate systems like 24TET, etc. So to the grandparent post, don't worry - there has never been a time when so many young people are playing with and exploiting tuning systems to create interesting music.