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Ask HN: What startup/technology is on your 'to watch' list?

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Re: Ask HN: What startup/technology is on your 'to watch' list?

#591

A friend of mine is working on coscout. It's in beta right now, but he showed me some pretty insane machine learning based insights for companies, investors and founders. Things like - When will this company raise the next round? - What is the net worth of ? - What is the probability that this investor will invest in you? (given your sector, founder age, pedigree, gender, market conditions, do you have an MVP or not…

Feedback loops in this sort of thing always scare me. For example - say people of one demographic are less likely to fund raise, so the model says they're less likely to succeed, so investors using the model don't invest in them and they are put at an even further disadvantage. And so something that is inherently data driven can end up moving further away from the meritocratic ideal it's likely trying for.

And the thing is, it's hard to get this bias out of models - almost everything ends up correlating to age, race, gender and so on - zip codes, income, schools, past employers, etc.

Re: Ask HN: What startup/technology is on your 'to watch' list?

#592
post #486

Earlier quoted context omitted.

Well, let me recomend something else, check asrock mini-itx motherboards with on-board cpu. You can get those for ~150 euros, throw in some ram (~60 euros) and some disk (100euro) + some chasis (Phenom mini-itx for instance, ~100euros). For home server this will work great :) I am running home server (100% self hosted including emails) with J1900-itx motherboard with 20Tb of disk space (zraid) for years. No need to b…

Well, your described bundle would be over 400€ then you can purchase used PS4 at least half that price and even cheaper.

Yes, but ps4 is gaming rig and you will have to jailbreak it every reboot. It depends on what you intend to run, raspberry pi 4 and sd card could be just more then enough for some people. Those prices were over the thumb, my motherboard with cpu is there since 2014 and is now $60 while it is more than enough and with going minimal (ram, chasis, disk - with ps4 you will get 1tb at most) you can pull it of under ps4 price. At the end, if you divide those 400 euros by 6 years, you are at price of 5.55 euro / month (not to mention you can reuse chasis and disks when upgrading) and it is low power setup (measured with 4 disks was 33 watts).

Jailbreaking could be nice for other unnamed purposes.

Re: Ask HN: What startup/technology is on your 'to watch' list?

#593
post #409

Earlier quoted context omitted.

I am talking about work being done in clinical trials at reputable medical clinics. They may be mistaken but I don't think it's "silliness." Here is a recent clinical trial evaluating UVBI https://www.tandfonline.com/doi/full/10.1080/2331205X.2019.1... Of course there are many other mainstream treatments that came from somewhat oddball ideas: Sister Kenney's treatments for polio, the Nobel prize winning discovery by…

It should never have been signed off on by an IRB. It is irresponsible and horrific that this has been trialed on people in this century.

I suspect this may be a case of "the dose makes the poison."

You may be generalizing from a specific experience or specific experiment and rejecting a modality that may have significant efficacy.

It's hard to tell what you are basing your assertions on because you offer no specifics. My "watch list" interest is based on the number of positive experimental results and ongoing investigations of the technique.

Re: Ask HN: What startup/technology is on your 'to watch' list?

#594
post #108

VR. It seems just about ready, but still a little too expensive. While good games are obviously already there, I'm more curious about work. Would an infinite desktop with an appropriate interface beat the reliable old 2x24" screen setup I have? I think it could.

I've had so many moments in VR where I could glimpse the future, I'm definitely bullish. The problems seem incrementally solvable - display resolution portability and comfort seem like they are easy enough to solve with time, and better/higher fidelity inputs.

A big thing with it as well I think will be focus, I'd love to be able to entirely shut out the world while working on something for 90 minutes or so.

This is one where I think it'll get to be good enough outside of niche gaming and just take off - my prediction is it'll take about 6 more years (i.e. 3 more release cycles) before the hardware is past the post.

Re: Ask HN: What startup/technology is on your 'to watch' list?

#596
post #557

Earlier quoted context omitted.

To an average user, Google in 2003 was a search page. In 2004+, it was essential internet infrastructure. That's a pretty big difference.

Gmail is popular but in the grand scheme of things it’s not that popular for email. I’m sure that most people get most of their utility from email from their corporate email. Their personal email is mostly used for distant relationship type communications. Most personal interactions these days happen via messaging and social media. AKA “Email is for old people”. Also, a lot of computer use is via mobile these days an…

It's pretty popular for email, at 25%+ market share [1]. That's a LOT of information to mine.

And point about conversations moving to post-email protocols, but email is certainly still up there with HTTP as a bedrock standard that everyone eventually touches.

Without pushing JavaScript and a full featured web client, it's fair to say Google wouldn't have grown as quickly and be nearly as dominant today.

As for their move to full mobile app, I think it's a bit of a different calculation when you happen to own the OS that powers ~75% of all mobile phones [2]. ;)

Suffice to say, I don't think Google has the same troubles as other developers. (Exception to security policy, for my first party app? Sure!)

[1] https://www.statista.com/chart/17570/most-popular-email-clie...

[2] https://www.statista.com/topics/3778/mobile-operating-system...

Re: Ask HN: What startup/technology is on your 'to watch' list?

#598

https://immersedvr.com/ Virtual monitors in an Oculus Quest that actually works. What’s coming up that will be amazing is hand controls (including a virtual keyboard) and conferencing and collaboration tools.

Couldn’t figure out how to add virtual monitors

Re: Ask HN: What startup/technology is on your 'to watch' list?

#599
post #141

Earlier quoted context omitted.

I look forward to in browser DLL hell /s I'm cautiously optimistic about blazor, it definitely makes streaming data to the Dom much easier

Blazor seems like the only one application of WASM at the moment that goes in the completely wrong direction. People are already whining about JS bundle size and even the small .net runtimes are >60kb. Yew on the other hand seems to fit right into what WebAssembly was made for.

For every person whining about 60k JS there are 10 creating 10MB web app.

Re: Ask HN: What startup/technology is on your 'to watch' list?

#600

Optical Coherence Tomography (OCT) occupies a intermediate position in accuracy / skin depth for soft tissue between ultrasound and MRI Optically pumped magnetometers (OPM) approaches SQUID level accuracy without need for supercooled device, can be worn or used as a contact sensor like ultrasound. LoRA long range (10km +) low power sub-gigahertz radio frequency protocol useful for battery powered IoT devices transmit…

Neat list. Thanks. I have chronic graft-versus host disease. Side effect of a bone marrow transplant. Mostly effects my skin, which changes color, gets thinner, and in advances stages hardens (aka marbleization). GVHD is wicked hard to diagnose, monitor. Skin biopsies and normal digital photos. I've asked my misc doctors (at FHCRC, SCCA, Univ of Wash) over the years about using UV to better diagnose skin conditions.…

OCT is a recognized diagnostic modality in dermatology and worth discussing with your doctors. Here are some references:

https://www.mdedge.com/dermatology/article/146053/melanoma/o...

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5946785/

http://www.octnews.org/category/5/dermatology/

and here is a clinic that talks about using it to assess skin: https://dermnetnz.org/topics/optical-coherence-tomography/

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