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Ask HN: What startup/technology is on your 'to watch' list?

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Re: Ask HN: What startup/technology is on your 'to watch' list?

#102
post #95

Self-driving cars. Now that the hype is over and the fake-it-til-you-make-it crowd has tanked, there's progress. Slowly, the LIDARs get cheaper, the radars get more resolution, and the software improves. UE5's rendering approach. They finally figured out how to use the GPU to do level of detail. Games can now climb out of the Uncanny Valley. The Playstation 5. 8 CPUs at 3.2GHz each, 24GB of RAM, 14 teraflops of GPU,…

> C++ getting serious about safety. Buffer overflows and bad pointers should have been eliminated decades ago. We've known how for a long time.

Would love some links to read over weekend. Thanks!

Re: Ask HN: What startup/technology is on your 'to watch' list?

#103

Optical Coherence Tomography (OCT) occupies a intermediate position in accuracy / skin depth for soft tissue between ultrasound and MRI Optically pumped magnetometers (OPM) approaches SQUID level accuracy without need for supercooled device, can be worn or used as a contact sensor like ultrasound. LoRA long range (10km +) low power sub-gigahertz radio frequency protocol useful for battery powered IoT devices transmit…

Oh man, I used to research in OCT for deep brain stimulation! It's pretty cool tech, that is for sure. It's got a huge market for bio applications and certain industrials.

That said, optics is a super finicky field. You can come in and get a Nobel for 5 hours work, or you can spend 50 years in a dark room trying to get things together. Alignment is crazy difficult, thought it seems it shouldn't be.

Anyone that wants to dive into optics: Just do it for 2 years, no more.

Re: Ask HN: What startup/technology is on your 'to watch' list?

#104
post #95

Self-driving cars. Now that the hype is over and the fake-it-til-you-make-it crowd has tanked, there's progress. Slowly, the LIDARs get cheaper, the radars get more resolution, and the software improves. UE5's rendering approach. They finally figured out how to use the GPU to do level of detail. Games can now climb out of the Uncanny Valley. The Playstation 5. 8 CPUs at 3.2GHz each, 24GB of RAM, 14 teraflops of GPU,…

Maybe it was a purposeful reference, but PlayStations have indeed been linked to create a supercomputer: https://phys.org/news/2010-12-air-playstation-3s-supercomput...

Re: Ask HN: What startup/technology is on your 'to watch' list?

#105

I recently wondered if you can take your saliva, or blood, and get a diffraction scan of it. Kind of like a spectrograph. You’d feed this into a machine learning system, and it would match up your pattern against a known dataset. This might allow for faster identification and recognition, of known viruses and diseases. Especially if the technology can identify the virus from just your spit.

Current methods can pretty easily identify the virus from just your spit (in fact, that's a protocol that is pretty widely used for different applications). The biggest problem is that normally you need to concentrate the virus in order to get detectable range for earlier days of infection. Seems like the range is approximately ~2 days earlier with concentrating vs spit only, which is actually significant.

All diseases (other than prions) are just nucleic acid, so that's already possible. Nanopore sequencing is the future and will eat most other technologies lunch.

Re: Ask HN: What startup/technology is on your 'to watch' list?

#106
post #37

Roam Research https://roamresearch.com/ A tool for networked thought that has been an effective "Second Brain" for me. I'm writing way more than ever through daily notes and the bi-directly linking of notes enables me to build smarter connections between notes and structure my thoughts in a way that helps me take more action and build stronger ideas over time.

How's this different from hypertext? (I genuinely don't know)

Re: Ask HN: What startup/technology is on your 'to watch' list?

#107

Materialize https://materialize.io/ Incremental update/materialization of database views with joins and aggregates is super interesting. It enables listening to data changes, not just on a row level, but on a view level. It's an approach that may completely solve the problem of cache invalidation of relational data. Imagine a memcache server, except it now also guaranties consistency. In addition, being able to liste…

+1, very excited about this.

They're marketing it in the OLAP space right now, but at some point I'd like to try integrating it with a web framework I've been working on.[1][2] It'd be a more powerful version of firebase's real-time queries. Firebase's queries don't let you do joins; you basically can just filter over a single table at a time. So you have to listen to multiple queries and then join the results by hand on the frontend. Doesn't work if you're aggregating over a set of entities that's too large to send to the client (or that the client isn't authorized to see).

[1] https://findka.com/blog/migrating-to-biff/ [2] https://github.com/jacobobryant/biff

Re: Ask HN: What startup/technology is on your 'to watch' list?

#108
VR. It seems just about ready, but still a little too expensive.

While good games are obviously already there, I'm more curious about work. Would an infinite desktop with an appropriate interface beat the reliable old 2x24" screen setup I have? I think it could.

Re: Ask HN: What startup/technology is on your 'to watch' list?

#109
If anyone is particularly brave, we are a new platform which is like Firebase, except it's built with Postgres:

https://app.supabase.io

We are are essentially rebuilding [DabbleDB](https://en.wikipedia.org/wiki/Dabble_DB) for the UI, and you get a bunch of middleware which is auto-generated: REST APIs, Realtime (CDC), auto-updating documentation. Also we will tackle some of the more difficult tasks for Postgres like replicating your database close to your users.

Also we're opensource! https://github.com/supabase/

Re: Ask HN: What startup/technology is on your 'to watch' list?

#110
post #99

Optogenetics [0]. Light changes electrical behavior in cells. AKA, point laser, neurons fire, I know kung-fu Memristors [1] Rebuilding the entire computer from EE basics. New 'color' added to EE spectrum, now computers process huge datasets on a watch battery CRISPR-CaS9 [2] Tricks bacteria used to keeps viruses out are pretty slick. Crtl-C, Ctrl-V for gene editing. $100B technology, easily. Strangely (encouragingly?…

I was excited for memristors in 2008 when HP announced they were right around the corner. They even built a new computer and a new OS to take advantage of memristors [1]. And then it never happened and no one has ever built one and it’s pretty much vaporware. I would be hesitant to trust anyone who says they’re anywhere close. It’s just not a technology that actually exists.

[1] https://www.extremetech.com/extreme/207897-hp-kills-the-mach...

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